The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Myocardial KATPChannels in Preconditioning
Abstract
Abstract—We are on the brink of harnessing the cell’s natural defenses against ischemia and reperfusion injury after years of research into the destructive and protective mechanisms involved. Since the discovery of ischemic preconditioning, the surface receptors and signal transduction pathways underlying this phenomenon have been clarified, but many questions remain about the downstream targets that ultimately protect the cell. ATP-sensitive K+(K ATP) channels are thought to play a role in protection, but their mechanism of action has been unclear. Accumulating evidence now suggests that the location of the K ATP channels relevant to cytoprotection may be on the mitochondrial inner membrane instead of on the sarcolemma of the cardiac cell. This review discusses recent findings and unanswered questions about the role of K ATP channels in preconditioning and protection.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vanden Hoek, T. L., Becker, L. B., Shao, Z., Li, C., & Schumacker, P. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18092 · Cited by 721
Sulfonylurea and K+-Channel Opener Sensitivity of KATP Channels
Koster, J. C., Sha, Q., & Nichols, C. G. (1999) · The Journal of General Physiology · doi:10.1085/jgp.114.2.203 · Cited by 97
The tolbutamide site of SUR1 and a mechanism for its functional coupling to KATP channel closure
Babenko, A. P., Gonzalez, G., & Bryan, J. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01215-6 · Cited by 63
Cited by
Baines, C. P., Song, C.-X., Zheng, Y.-T., Wang, G.-W., Zhang, J., Wang, O.-L., Guo, Y., Bolli, R., Cardwell, E. M., & Ping, P. (2003) · Circulation Research · doi:10.1161/01.res.0000069215.36389.8d · Cited by 450
Evidence for Mitochondrial K + Channels and Their Role in Cardioprotection
O’Rourke, B. (2004) · Circulation Research · doi:10.1161/01.res.0000117583.66950.43 · Cited by 444
Self-citationCardioprotection: Nitric Oxide, Protein Kinases, and Mitochondria
Heusch, G., Boengler, K., & Schulz, R. (2008) · Circulation · doi:10.1161/circulationaha.108.805242 · Cited by 441
Baines, C. P., Zhang, J., Wang, G.-W., Zheng, Y.-T., Xiu, J. X., Cardwell, E. M., Bolli, R., & Ping, P. (2002) · Circulation Research · doi:10.1161/01.res.0000012702.90501.8d · Cited by 429
The role of mitochondria in protection of the heart by preconditioning
Halestrap, A. P., Clarke, S. J., & Khaliulin, I. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2007.05.008 · Cited by 390
Metadata
- Authors
- O’Rourke, B.
- Venue
- Circulation Research
- Published
- 2000-11-10
- Volume
- 87
- Issue
- 10
- Pages
- 845-855
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2128432446
- Cited by
- 347
- References
- 3
- FWCI
- 19.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Myocardial KATPChannels in Preconditioning. https://app.cochat.ai/papers/10.1161/01.res.87.10.845
- The paper
- O’Rourke, B. (2000). Myocardial KATPChannels in Preconditioning. Circulation Research. https://doi.org/10.1161/01.res.87.10.845
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
