The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Evidence for Mitochondrial K + Channels and Their Role in Cardioprotection
Open accessAbstract
Twenty years after the discovery of sarcolemmal ATP-sensitive K + channels and 12 years after the discovery of mitochondrial K ATP (mitoK ATP ) channels, progress has been remarkable, but many questions remain. In the case of the former, detailed structural information is available, and it is well accepted that the channel couples bioenergetics to cellular electrical excitability; however, in the heart, a clear physiological or pathophysiological role has yet to be defined. For mitoK ATP , structural information is lacking, but there is abundant evidence linking the opening of the channel to protection against ischemia-reperfusion injury or apoptosis. This review updates recent progress in understanding the physiological role of mitoK ATP and highlights outstanding questions and controversies, with the intent of stimulating additional investigation on this topic.
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Vanden Hoek, T. L., Becker, L. B., Shao, Z., Li, C., & Schumacker, P. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18092 · Cited by 721
KATP channel‐independent targets of diazoxide and 5‐hydroxydecanoate in the heart
Hanley, P. J., Mickel, M., Löffler, M., Brandt, U., & Daut, J. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.023960 · Cited by 320
The nitric oxide hypothesis of late preconditioning
Bolli, R., Dawn, B., Tang, X.-L., Qiu, Y., Ping, P., Xuan, Y.-T., Jones, W. K., Takano, H., Guo, Y., & Zhang, J. (1998) · Basic Research in Cardiology · doi:10.1007/s003950050101 · Cited by 270
Ardehali, H., Chen, Z., Ko, Y., Mejía-Alvarez, R., & Marbán, E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401703101 · Cited by 215
Mitochondrial KATP channels in preconditioning
Oldenburg, O. (2003) · Journal of Molecular and Cellular Cardiology · doi:10.1016/s0022-2828(03)00115-9 · Cited by 94
Do Modulators of the Mitochondrial KATP Channel Change the Function of Mitochondria in Situ?
Ovide-Bordeaux, S., Ventura-Clapier, R., & Veksler, V. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005772200 · Cited by 60
Cited by
The ubiquitous role of nitric oxide in cardioprotection
Jones, S. P., & Bolli, R. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2005.09.011 · Cited by 434
The role of mitochondria in protection of the heart by preconditioning
Halestrap, A. P., Clarke, S. J., & Khaliulin, I. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2007.05.008 · Cited by 390
Hong, J., Zhang, Y., Lai, S., Lv, A., Su, Q., Dong, Y., Zhou, Z., Tang, W., Zhao, J., Cui, L., et al. (2013) · Diabetes Care · doi:10.2337/dc12-0719 · Cited by 366
Connexin 43 in cardiomyocyte mitochondria and its increase by ischemic preconditioning
BOENGLER, K., DODONI, G., RODRIGUEZSINOVAS, A., CABESTRERO, A., RUIZMEANA, M., GRES, P., KONIETZKA, I., LOPEZIGLESIAS, C., GARCIADORADO, D., & DILISA, F. (2005) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.04.014 · Cited by 300
Chen, Q., Camara, A. K. S., Stowe, D. F., Hoppel, C. L., & Lesnefsky, E. J. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00270.2006 · Cited by 271
Metadata
- Authors
- O’Rourke, B.
- Venue
- Circulation Research
- Published
- 2004-03-05
- Volume
- 94
- Issue
- 4
- Pages
- 420-432
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2129978185
- Cited by
- 444
- References
- 6
- FWCI
- 30.65
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
