The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Eligibility for Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke: A Population-Based Study
Open accessAbstract
Background and Purpose— Acute ischemic stroke patients are infrequently treated with recombinant tissue plasminogen activator (rtPA). We present unique population-based data regarding the eligibility of ischemic stroke patients for rtPA treatment. Methods— All ischemic strokes presenting to an emergency department (ED) within a biracial population of 1.3 million were identified. The patient was considered eligible for rtPA on the basis of exclusion criteria from the National Institute of Neurological Disorders and Stroke rtPA trial. Results— Of 2308 ischemic strokes, 1849 presented to an ED. Only 22% of all ischemic strokes in the population arrived in the ED in <3 hours from symptom onset; of these, 209 (51%) were ineligible for rtPA on the basis of mild stroke severity, medical and surgical history, or blood tests. Conclusions— In our population in 1993 to 1994, 8% of all ischemic stroke patients presented to an ED within 3 hours and met other eligibility criteria for rtPA. Even if time were not an exclusion for rtPA, only 29% of all ischemic strokes in our population would have otherwise been eligible for rtPA.
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Cites
Broderick, J., Brott, T., Kothari, R., Miller, R., Khoury, J., Pancioli, A., Gebel, J., Mills, D., Minneci, L., & Shukla, R. (1998) · Stroke · doi:10.1161/01.str.29.2.415 · Cited by 752
Self-citationWhy are stroke patients excluded from TPA therapy?: An analysis of patient eligibility
Barber, P. A., Zhang, J., Demchuk, A. M., Hill, M. D., & Buchan, A. M. (2001) · Neurology · doi:10.1212/wnl.56.8.1015 · Cited by 704
Public Perception of Stroke Warning Signs and Knowledge of Potential Risk Factors
Pancioli, A. M. (1998) · JAMA · doi:10.1001/jama.279.16.1288 · Cited by 520
Self-citationTrends in Community Knowledge of the Warning Signs and Risk Factors for Stroke
Schneider, A. T., Pancioli, A. M., Khoury, J. C., Rademacher, E., Tuchfarber, A., Miller, R., Woo, D., Kissela, B., & Broderick, J. P. (2003) · JAMA · doi:10.1001/jama.289.3.343 · Cited by 348
Self-citationSchroeder, E. B., Rosamond, W. D., Morris, D. L., Evenson, K. R., & Hinn, A. R. (2000) · Stroke · doi:10.1161/01.str.31.11.2591 · Cited by 279
The Paul Coverdell National Acute Stroke Registry
Reeves, M. J., Broderick, J. P., Frankel, M., LaBresh, K. A., Schwamm, L. H., Moomaw, C. J., Weiss, P., & Katzan, I. L. (2006) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2006.08.007 · Cited by 52
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Heart Disease and Stroke Statistics—2010 Update: A Report From the American Heart Association
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R. J., Brown, T. M., Carnethon, M., Dai, S., De Simone, G., Ferguson, T. B., Ford, E., Furie, K., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192667 · Cited by 5,700
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191261 · Cited by 3,140
Demaerschalk, B. M., Kleindorfer, D. O., Adeoye, O. M., Demchuk, A. M., Fugate, J. E., Grotta, J. C., Khalessi, A. A., Levy, E. I., Palesch, Y. Y., Prabhakaran, S., et al. (2016) · Stroke · doi:10.1161/str.0000000000000086 · Cited by 670
Self-citationTask Force Members, Schwamm, L. H., Pancioli, A., Acker, J. E., Goldstein, L. B., Zorowitz, R. D., Shephard, T. J., Moyer, P., Gorman, M., Johnston, S. C., et al. (2005) · Stroke · doi:10.1161/01.str.0000158165.42884.4f · Cited by 313
Self-citationSchwamm, L. H., Ali, S. F., Reeves, M. J., Smith, E. E., Saver, J. L., Messe, S., Bhatt, D. L., Grau-Sepulveda, M. V., Peterson, E. D., & Fonarow, G. C. (2013) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.111.000095 · Cited by 305
Metadata
- Authors
- Kleindorfer, D., Kissela, B., Schneider, A., Woo, D., Khoury, J., Miller, R., Alwell, K., Gebel, J., Szaflarski, J., Pancioli, A., Jauch, E., Moomaw, C., Shukla, R., & Broderick, J. P.
- Venue
- Stroke
- Published
- 2004-02
- Volume
- 35
- Issue
- 2
- Pages
- e27-9
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2133758580
- Cited by
- 299
- References
- 6
- FWCI
- 11.25
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Eligibility for Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke: A Population-Based Study. https://app.cochat.ai/papers/10.1161/01.str.0000109767.11426.17
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- Kleindorfer, D., Kissela, B., Schneider, A., Woo, D., Khoury, J., Miller, R., Alwell, K., Gebel, J., Szaflarski, J., Pancioli, A., Jauch, E., Moomaw, C., Shukla, R., & Broderick, J. P. (2004). Eligibility for Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke: A Population-Based Study. Stroke. https://doi.org/10.1161/01.str.0000109767.11426.17
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