The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Transient Ischemic Attacks Before Ischemic Stroke: Preconditioning the Human Brain?: A Multicenter Magnetic Resonance Imaging Study
Abstract
Background and Purpose— We investigated whether transient ischemic attacks (TIAs) before stroke can induce tolerance by raising the threshold of tissue vulnerability in the human brain. Methods— Sixty-five patients with first-ever ischemic territorial stroke received diffusion- and perfusion-weighted MRI within 12 hours of symptom onset. Epidemiological and clinical data, lesion volumes in T2, apparent diffusion coefficient (ADC) maps and perfusion maps, and cerebral blood flow and cerebral blood volume values were compared between patients with and without a prodromal TIA. Results— Despite similar size and severity of the perfusion deficit, initial diffusion lesions tended to be smaller and final infarct volumes were significantly reduced (final T2: 9.1 [interquartile range, 19.7] versus 36.5 [91.2] mL; P =0.014) in patients with a history of TIA (n=16). This was associated with milder clinical deficits. Conclusions— The beneficial effect of TIAs on lesion size in ADC and T2 suggests the existence of endogenous neuroprotection in the human brain.
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Cites
Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank
Grau, A. J., Weimar, C., Buggle, F., Heinrich, A., Goertler, M., Neumaier, S., Glahn, J., Brandt, T., Hacke, W., & Diener, H.-C. (2001) · Stroke · doi:10.1161/hs1101.098524 · Cited by 998
Wardlaw, J. M., Dennis, M. S., Warlow, C. P., & Sandercock, P. A. (2001) · Annals of Neurology · doi:10.1002/ana.1082 · Cited by 93
Cited by
Cerebral preconditioning and ischaemic tolerance
Gidday, J. M. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1927 · Cited by 751
Kalogeris, T., Baines, C. P., Krenz, M., & Korthuis, R. J. (2016) · Comprehensive Physiology · doi:10.1002/cphy.c160006 · Cited by 718
Dirnagl, U., Becker, K., & Meisel, A. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70054-7 · Cited by 587
Systemic infection, inflammation and acute ischemic stroke
McColl, B. W., Allan, S. M., & Rothwell, N. J. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.08.019 · Cited by 318
Martínez-García, M.-A., Campos-Rodríguez, F., Catalán-Serra, P., Soler-Cataluña, J.-J., Almeida-Gonzalez, C., De la Cruz Morón, I., Durán-Cantolla, J., & Montserrat, J.-M. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201203-0448oc · Cited by 298
Metadata
- Authors
- Wegener, S., Gottschalk, B., Jovanovic, V., Knab, R., Fiebach, J. B., Schellinger, P. D., Kucinski, T., Jungehülsing, G. J., Brunecker, P., Müller, B., Banasik, A., Amberger, N., Wernecke, K. D., Siebler, M., Röther, J., Villringer, A., & Weih, M.
- Venue
- Stroke
- Published
- 2004-03
- Volume
- 35
- Issue
- 3
- Pages
- 616-621
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2153872342
- Cited by
- 303
- References
- 2
- FWCI
- 11.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wegener, S., Gottschalk, B., Jovanovic, V., Knab, R., Fiebach, J. B., Schellinger, P. D., Kucinski, T., Jungehülsing, G. J., Brunecker, P., Müller, B., Banasik, A., Amberger, N., Wernecke, K. D., Siebler, M., Röther, J., Villringer, A., & Weih, M. (2004). Transient Ischemic Attacks Before Ischemic Stroke: Preconditioning the Human Brain?: A Multicenter Magnetic Resonance Imaging Study. Stroke. https://doi.org/10.1161/01.str.0000115767.17923.6a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
