The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Measurements of acute cerebral infarction: lesion size by computed tomography.
Abstract
As part of a prospective therapy study of 65 patients with acute, nonhemorrhagic, cerebral infarction, computed tomographic scans of the head were obtained at admission, 7-10 days, and 3 months. The scans were analyzed for the presence, site, size, and volume measurement of the infarction. At 7-10 days, the mean infarction volume as measured by computed tomography was 55 cm3 or about 4 x 4 x 3.5 cm (range = 0-507 cm3). At 3 months, the mean infarction volume decreased by 25% to 41 cm3. For the 26 scans showing infarction at the time of admission, the mean lesion volume was 33 cm3 at admission, 51 cm3 at 7-10 days, and 49 cm3 at 3 months. With lesion size at 7-10 days expressed as percentage of total brain volume, the mean infarction size was only 5%. Of the 49 patients with lesions revealed by computed tomography at 7-10 days, 20 had an infarction of 1% or less of total brain volume, while only six had an infarction of 20% or more of total brain volume. The lesion volumes as measured by the 7-10-day computed tomography correlated with the neurologic examination scores on admission (Spearman's rank-order correlation = 0.78) and with the scores at 1 week (Spearman's rank-order correlation = 0.79).
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Cites
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Classification and natural history of clinically identifiable subtypes of cerebral infarction
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Safety study of tirilazad mesylate in patients with acute ischemic stroke (STIPAS).
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Metadata
- Authors
- Brott, T., Marler, J. R., Olinger, C. P., Adams, H. P., Tomsick, T., Barsan, W. G., Biller, J., Eberle, R., Hertzberg, V, & Walker, M.
- Venue
- Stroke
- Published
- 1989-07
- Volume
- 20
- Issue
- 7
- Pages
- 871-875
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2093728612
- Cited by
- 384
- References
- 11
- FWCI
- 4.81
- Type
- journal article
- Language
- en
- Open access
- closed
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- Brott, T., Marler, J. R., Olinger, C. P., Adams, H. P., Tomsick, T., Barsan, W. G., Biller, J., Eberle, R., Hertzberg, V, & Walker, M. (1989). Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke. https://doi.org/10.1161/01.str.20.7.871
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