The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
PECAM-1: A Multi-Functional Molecule in Inflammation and Vascular Biology
Open accessAbstract
Platelet endothelial cell adhesion molecule-1 (PECAM-1 or CD31) is a molecule expressed on all cells within the vascular compartment, being expressed to different degrees on most leukocyte sub-types, platelets, and on endothelial cells where its expression is largely concentrated at junctions between adjacent cells. As well as exhibiting adhesive properties, PECAM-1 is an efficient signaling molecule and is now known to have diverse roles in vascular biology including roles in angiogenesis, platelet function, and thrombosis, mechanosensing of endothelial cell response to fluid shear stress, and regulation of multiple stages of leukocyte migration through venular walls. This review will focus on some new developments with respect to the role of PECAM-1 in inflammation and vascular biology, highlighting the emerging complexities associated with the functions of this unique molecule.
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Cites
Inflammation, Atherosclerosis, and Coronary Artery Disease
Hansson, G. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043430 · Cited by 8,773
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
Tzima, E., Irani-Tehrani, M., Kiosses, W. B., Dejana, E., Schultz, D. A., Engelhardt, B., Cao, G., DeLisser, H., & Schwartz, M. A. (2005) · Nature · doi:10.1038/nature03952 · Cited by 1,711
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
Tedgui, A., & Mallat, Z. (2006) · Physiological Reviews · doi:10.1152/physrev.00024.2005 · Cited by 1,701
Endothelial cell–cell junctions: happy together
Dejana, E. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1357 · Cited by 1,188
PECAM-1 is required for transendothelial migration of leukocytes.
Muller, W. A., Weigl, S. A., Deng, X., & Phillips, D. M. (1993) · The Journal of experimental medicine · doi:10.1084/jem.178.2.449 · Cited by 1,152
PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily
Newman, P. J., Berndt, M. C., Gorski, J., White, G. C., Lyman, S., Paddock, C., & Muller, W. A. (1990) · Science · doi:10.1126/science.1690453 · Cited by 950
Leukocyte–endothelial-cell interactions in leukocyte transmigration and the inflammatory response
Muller, W. A. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00117-0 · Cited by 823
Newman, P. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119129 · Cited by 664
Hajra, L., Evans, A. I., Chen, M., Hyduk, S. J., Collins, T., & Cybulsky, M. I. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.16.9052 · Cited by 574
CD99 plays a major role in the migration of monocytes through endothelial junctions
Schenkel, A. R., Mamdouh, Z., Chen, X., Liebman, R. M., & Muller, W. A. (2002) · Nature Immunology · doi:10.1038/ni749 · Cited by 509
Cited by
Liver sinusoidal endothelial cells: Physiology and role in liver diseases
Poisson, J., Lemoinne, S., Boulanger, C., Durand, F., Moreau, R., Valla, D., & Rautou, P.-E. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2016.07.009 · Cited by 1,047
Brain endothelial cells and the glio-vascular complex
Wolburg, H., Noell, S., Mack, A., Wolburg-Buchholz, K., & Fallier-Becker, P. (2009) · Cell and Tissue Research · doi:10.1007/s00441-008-0658-9 · Cited by 438
Effects of shear stress on endothelial cells: go with the flow
Chistiakov, D. A., Orekhov, A. N., & Bobryshev, Y. V. (2017) · Acta Physiologica · doi:10.1111/apha.12725 · Cited by 431
PECAM-1: regulator of endothelial junctional integrity
Privratsky, J. R., & Newman, P. J. (2014) · Cell and Tissue Research · doi:10.1007/s00441-013-1779-3 · Cited by 366
Passing the Vascular Barrier: Endothelial Signaling Processes Controlling Extravasation
Wettschureck, N., Strilic, B., & Offermanns, S. (2019) · Physiological Reviews · doi:10.1152/physrev.00037.2018 · Cited by 286
Metadata
- Authors
- Woodfin, A., Voisin, M.-B., & Nourshargh, S.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2007-12
- Volume
- 27
- Issue
- 12
- Pages
- 2514-2523
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2119303378
- Cited by
- 583
- References
- 72
- FWCI
- 14.81
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Woodfin, A., Voisin, M.-B., & Nourshargh, S. (2007). PECAM-1: A Multi-Functional Molecule in Inflammation and Vascular Biology. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/atvbaha.107.151456
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
