The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Integrins: The Keys to Unlocking Angiogenesis
Abstract
Angiogenesis, the formation of new blood vessels from preexisting vasculature, contributes to the pathogenesis of many disorders, including ischemic diseases and cancer. Integrins are cell adhesion molecules that are expressed on the surface of endothelial cells and pericytes, making them potential targets for antiangiogenic therapy. Here we review the contribution of endothelial and mural cell integrins to angiogenesis and highlight their potential as antiangiogenesis targets.
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Cites
Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
Brooks, P. C., Montgomery, A. M. P., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G., & Cheresh, D. A. (1994) · Cell · doi:10.1016/0092-8674(94)90007-8 · Cited by 2,262
Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo
Kisanuki, Y. Y., Hammer, R. E., Miyazaki, J.-I., Williams, S. C., Richardson, J. A., & Yanagisawa, M. (2001) · Developmental Biology · doi:10.1006/dbio.2000.0106 · Cited by 1,241
Tong, R. T., Boucher, Y., Kozin, S. V., Winkler, F., Hicklin, D. J., & Jain, R. K. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0074 · Cited by 1,189
Leu, S.-J., Lam, S. C.-T., & Lau, L. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209288200 · Cited by 247
Identification of a novel integrin α6β1 binding site in the angiogenic Inducer CCN1 (CYR61)
Leu, S.-J., Liu, Y., Chen, N., Chen, C.-C., Lam, S. C.-T., & Lau, L. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305862200 · Cited by 131
Cited by
Use of the mouse aortic ring assay to study angiogenesis
Baker, M., Robinson, S. D., Lechertier, T., Barber, P. R., Tavora, B., D'Amico, G., Jones, D. T., Vojnovic, B., & Hodivala-Dilke, K. (2012) · Nature Protocols · doi:10.1038/nprot.2011.435 · Cited by 477
Self-citationThe role of tumour-stromal interactions in modifying drug response: challenges and opportunities
McMillin, D. W., Negri, J. M., & Mitsiades, C. S. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3870 · Cited by 474
Mettu, P. S., Allingham, M. J., & Cousins, S. W. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100906 · Cited by 370
Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment
Brown, N. F., & Marshall, J. F. (2019) · Cancers · doi:10.3390/cancers11091221 · Cited by 116
Non-collagenous ECM proteins in blood vessel morphogenesis and cancer
Kostourou, V., & Papalazarou, V. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.02.018 · Cited by 41
Metadata
- Authors
- Silva, R., D'Amico, G., Hodivala-Dilke, K. M., & Reynolds, L. E.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2008-10
- Volume
- 28
- Issue
- 10
- Pages
- 1703-1713
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W1965559724
- Cited by
- 255
- References
- 5
- FWCI
- 14.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Integrins: The Keys to Unlocking Angiogenesis. https://app.cochat.ai/papers/10.1161/atvbaha.108.172015
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- Silva, R., D'Amico, G., Hodivala-Dilke, K. M., & Reynolds, L. E. (2008). Integrins: The Keys to Unlocking Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/atvbaha.108.172015
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
