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Cited by 265

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Value of Clinician Assessment of Hemodynamics in Advanced Heart Failure: The ESCAPE Trial

Open access
Drazner, Mark H., Hellkamp, Anne S., Leier, Carl V., Shah, Monica R., Miller, Leslie W., Russell, Stuart D., Young, James B., Califf, Robert M., Nohria, Anju·2008·Circulation: Heart Failure

Abstract

Background— We determined whether estimated hemodynamics from history and physical examination (H&P) reflect invasive measurements and predict outcomes in advanced heart failure. The role of the H&P in medical decision making has declined in favor of diagnostic tests, perhaps because of the lack of evidence for utility. Methods and Results— We compared H&P estimates of filling pressures and cardiac index with invasive measurements in 194 patients in the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial. H&P estimates were compared with 6-month outcomes in 388 patients enrolled in ESCAPE. Measured right atrial pressure was <8 mm Hg in 82% of patients with right atrial pressure estimated from jugular veins as <8 mm Hg, and was >12 mm Hg in 70% of patients when estimated as >12 mm Hg. From the H&P, only estimated right atrial pressure ≥12 mm Hg (odds ratio, 4.6; P <0.001) and orthopnea ≥2 pillows (odds ratio, 3.6; P <0.05) were associated with pulmonary capillary wedge pressure ≥30 mm Hg. Estimated cardiac index did not reliably reflect the measured cardiac index ( P =0.09), but “cold” versus “warm” profile was associated with lower median measured cardiac index (1.75 versus 2.0 L/(min�m 2 ); P =0.004). In Cox regression analysis, discharge “cold” or “wet” profile conveyed a 50% increased risk of death or rehospitalization. Conclusions— In advanced heart failure, the presence of orthopnea and increased jugular venous pressure is useful to detect increased pulmonary capillary wedge pressure, and a global assessment of inadequate perfusion (“cold” profile) is useful to detect reduced cardiac index. Hemodynamic profiles estimated from the discharge H&P identify patients at increased risk of early events.

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Crossref · 10.1161/circheartfailure.108.769778

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Metadata

Authors
Drazner, M. H., Hellkamp, A. S., Leier, C. V., Shah, M. R., Miller, L. W., Russell, S. D., Young, J. B., Califf, R. M., & Nohria, A.
Venue
Circulation: Heart Failure
Published
2008-09
Volume
1
Issue
3
Pages
170-177
ISSN
  • 1941-3289 (ISSN-L)
  • 1941-3297
OpenAlex
W2140634971
Cited by
265
References
22
FWCI
6.60
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Value of Clinician Assessment of Hemodynamics in Advanced Heart Failure: The ESCAPE Trial. https://app.cochat.ai/papers/10.1161/circheartfailure.108.769778
The paper
Drazner, M. H., Hellkamp, A. S., Leier, C. V., Shah, M. R., Miller, L. W., Russell, S. D., Young, J. B., Califf, R. M., & Nohria, A. (2008). Value of Clinician Assessment of Hemodynamics in Advanced Heart Failure: The ESCAPE Trial. Circulation: Heart Failure. https://doi.org/10.1161/circheartfailure.108.769778

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.