The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Lifetime Analysis of Hospitalizations and Survival of Patients Newly Admitted With Heart Failure
Open accessAbstract
Background—: Hospital readmissions for heart failure (HF) contribute to increased morbidity and resource burden. Predictors of hospitalization and patterns of cardiovascular events over the lifetime of patients with HF have not been elucidated. Methods and Results—: We examined recurrent hospitalizations, cardiovascular events, and survival among newly discharged (April 1999–March 2001) patients with HF in the Enhanced Feedback For Effective Cardiac Treatment phase 1 study. During 10-year follow-up, we examined all new cardiovascular hospitalizations and selected predictors of readmission. Among 8543 patients (mean age, 77.4±10.5 years; 51.6% women) followed for 22 567 person-years, 60.7% had ischemic etiology, and 67.3% had HF with reduced ejection fraction (left ventricular ejection fraction ≤45% versus >45% [HF with preserved ejection fraction]). Overall, 10-year mortality was 98.8%, with 35 966 hospital readmissions occurring over the lifetime of the cohort. Adjusted hazards ratios (HRs) for first cardiovascular hospitalization were 1.36 for ischemic HF (95% CI, 1.28–1.44; P <0.001), 1.10 for HF with reduced ejection fraction (95% CI; 1.00–1.20; P =0.045), and 1.00 for men (95% CI, 0.94–1.06; P =0.979). On repeated-events time-to-event analysis, ischemic HF was a predictor of cardiovascular (HR, 1.24; 95% CI, 1.18–1.29), HF (HR, 1.20; 95% CI, 1.13–1.27), and coronary heart disease (HR, 2.01; 95% CI, 1.81–2.24) hospitalizations (all P <0.001). Of all recurrent HF hospitalizations, 26.8% occurred in the first and 39.8% in the last deciles of cohort survival duration. Similarly, 29.7% and 52.3% of all cardiovascular readmissions occurred in the first and last deciles of the cohort survival duration, respectively. Conclusions—: Among newly discharged patients with HF, cardiovascular events were clustered at early postdischarge and prefatal time periods, and were increased among those with ischemic etiology.
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Cites
Modeling Survival Data: Extending the Cox Model
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Rehospitalizations among Patients in the Medicare Fee-for-Service Program
Jencks, S. F., Williams, M. V., & Coleman, E. A. (2009) · New England Journal of Medicine · doi:10.1056/nejmsa0803563 · Cited by 5,164
Statistical Models and Methods for Lifetime Data
Lawless, J. F. (2002) · Wiley Series in Probability and Statistics · doi:10.1002/9781118033005 · Cited by 4,470
Outcome of Heart Failure with Preserved Ejection Fraction in a Population-Based Study
Bhatia, R. S., Tu, J. V., Lee, D. S., Austin, P. C., Fang, J., Haouzi, A., Gong, Y., & Liu, P. P. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa051530 · Cited by 1,967
Self-citationChecking the Cox model with cumulative sums of martingale-based residuals
LIN, D. Y., WEI, L. J., & YING, Z. (1993) · Biometrika · doi:10.1093/biomet/80.3.557 · Cited by 1,432
Competing Risk Regression Models for Epidemiologic Data
Lau, B., Cole, S. R., & Gange, S. J. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp107 · Cited by 1,403
Coronary-Artery Bypass Surgery in Patients with Left Ventricular Dysfunction
Velazquez, E. J., Lee, K. L., Deja, M. A., Jain, A., Sopko, G., Marchenko, A., Ali, I. S., Pohost, G., Gradinac, S., Abraham, W. T., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1100356 · Cited by 1,304
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Self-citationStatistical Models and Methods for Lifetime Data
Johnston, G. (2003) · Technometrics · doi:10.1198/tech.2003.s767 · Cited by 1,197
Fonarow, G. C., Stough, W. G., Abraham, W. T., Albert, N. M., Gheorghiade, M., Greenberg, B. H., O’Connor, C. M., Sun, J. L., Yancy, C. W., & Young, J. B. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.04.064 · Cited by 1,092
Cited by
The vulnerable phase after hospitalization for heart failure
Greene, S. J., Fonarow, G. C., Vaduganathan, M., Khan, S. S., Butler, J., & Gheorghiade, M. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.14 · Cited by 406
Wachter, R., Senni, M., Belohlavek, J., Straburzynska-Migaj, E., Witte, K. K., Kobalava, Z., Fonseca, C., Goncalvesova, E., Cavusoglu, Y., Fernandez, A., et al. (2019) · European Journal of Heart Failure · doi:10.1002/ejhf.1498 · Cited by 354
Effect of Rosuvastatin on Repeat Heart Failure Hospitalizations
Rogers, J. K., Jhund, P. S., Perez, A.-C., Böhm, M., Cleland, J. G., Gullestad, L., Kjekshus, J., van Veldhuisen, D. J., Wikstrand, J., Wedel, H., et al. (2014) · JACC: Heart Failure · doi:10.1016/j.jchf.2013.12.007 · Cited by 138
Sud, M., Yu, B., Wijeysundera, H. C., Austin, P. C., Ko, D. T., Braga, J., Cram, P., Spertus, J. A., Domanski, M., & Lee, D. S. (2017) · JACC Heart Failure · doi:10.1016/j.jchf.2017.03.012 · Cited by 135
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Metadata
- Authors
- Chun, S., Tu, J. V., Wijeysundera, H. C., Austin, P. C., Wang, X., Levy, D., & Lee, D. S.
- Venue
- Circulation: Heart Failure
- Published
- 2012-07
- Volume
- 5
- Issue
- 4
- Pages
- 414-421
- ISSN
- 1941-3289 (ISSN-L)
- 1941-3297
- OpenAlex
- W2011637231
- Cited by
- 288
- References
- 36
- FWCI
- 8.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Chun, S., Tu, J. V., Wijeysundera, H. C., Austin, P. C., Wang, X., Levy, D., & Lee, D. S. (2012). Lifetime Analysis of Hospitalizations and Survival of Patients Newly Admitted With Heart Failure. Circulation: Heart Failure. https://doi.org/10.1161/circheartfailure.111.964791
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