The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.
Emerging Role of MicroRNAs in Cardiovascular Biology
Abstract
The heart is among the most conserved organs of the body and is susceptible to defects more than any other organ. Heart malformations, in fact, occur in roughly 1% of newborns. Moreover, cardiovascular disease arising during adult life is among the main causes of morbidity and mortality in developed countries. It is not surprising, therefore, that much effort is being channeled into understanding the development, physiology, and pathology of the cardiovascular system. MicroRNAs, a newly discovered class of small ribonucleotide-based regulators of gene expression, are being implicated in an increasing number of biological processes, and the study of their role in cardiovascular biology is just beginning. Here, we briefly overview microRNAs in general and report on the recent findings regarding their importance for the heart and vasculature, in particular. The new insights that are being gained will permit not only a greater understanding of cardiovascular pathologies but also, hopefully, the development of novel therapeutic strategies.
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4 retracted
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Cited by
The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis
Wang, S., Aurora, A. B., Johnson, B. A., Qi, X., McAnally, J., Hill, J. A., Richardson, J. A., Bassel-Duby, R., & Olson, E. N. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.07.002 · Cited by 1,617
Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes
Zampetaki, A., Kiechl, S., Drozdov, I., Willeit, P., Mayr, U., Prokopi, M., Mayr, A., Weger, S., Oberhollenzer, F., Bonora, E., et al. (2010) · Circulation Research · doi:10.1161/circresaha.110.226357 · Cited by 1,283
Wang, D., Wang, J., Lu, M., Song, F., & Cui, Q. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq241 · Cited by 913
MicroRNAs: novel regulators in cardiac development and disease
Thum, T., Catalucci, D., & Bauersachs, J. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn137 · Cited by 377
Self-citationTransmiR v2.0: an updated transcription factor-microRNA regulation database
Tong, Z., Cui, Q., Wang, J., & Zhou, Y. (2019) · Nucleic Acids Research · doi:10.1093/nar/gky1023 · Cited by 356
Metadata
- Authors
- Latronico, M. V. G., Catalucci, D., & Condorelli, G.
- Venue
- Circulation Research
- Published
- 2007-12-07
- Volume
- 101
- Issue
- 12
- Pages
- 1225-1236
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2171232191
- Cited by
- 284
- References
- 111
- FWCI
- 6.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Latronico, M. V. G., Catalucci, D., & Condorelli, G. (2007). Emerging Role of MicroRNAs in Cardiovascular Biology. Circulation Research. https://doi.org/10.1161/circresaha.107.163147
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
