O -Linked GlcNAc Modification of Cardiac Myofilament Proteins: A Novel Regulator of Myocardial Contractile Function

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Diabetic Cardiomyopathy Revisited

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Cross-talk between GlcNAcylation and phosphorylation: Site-specific phosphorylation dynamics in response to globally elevated O -GlcNAc

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Characterization of a Mouse Monoclonal Antibody Specific for O-Linked N-Acetylglucosamine

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Cardioprotection by N -Acetylglucosamine Linkage to Cellular Proteins

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Mechanisms of [Ca2+]i Transient Decrease in Cardiomyopathy of db/db Type 2 Diabetic Mice

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Adenovirus-Mediated Overexpression of O -GlcNAcase Improves Contractile Function in the Diabetic Heart

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Dynamic Interplay between O-Linked N-Acetylglucosaminylation and Glycogen Synthase Kinase-3-dependent Phosphorylation

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Covalent and Noncovalent Modification of Thin Filament Action

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Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart

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Proteomic Analysis of Pharmacologically Preconditioned Cardiomyocytes Reveals Novel Phosphorylation of Myosin Light Chain 1

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Identification of O-linked N-Acetylglucosamine Proteins in Rat Skeletal Muscle Using Two-dimensional Gel Electrophoresis and Mass Spectrometry

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p21-Activated Kinase Increases the Calcium Sensitivity of Rat Triton-Skinned Cardiac Muscle Fiber Bundles via a Mechanism Potentially Involving Novel Phosphorylation of Troponin I

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Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts — Evidence for novel phosphorylation sites

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Depressed cardiac myofilament function in human diabetes mellitus

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O-Linked N-Acetylglucosaminylation Is Involved in the Ca2+ Activation Properties of Rat Skeletal Muscle

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Na+-K+ pumps in the transverse tubular system of skeletal muscle fibers preferentially use ATP from glycolysis

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Impact of osmotic compression on sarcomere structure and myofilament calcium sensitivity of isolated rat myocardium

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Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function

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O-GlcNAc level variations are associated with the development of skeletal muscle atrophy

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Developmental Difference in the Stimulation of Cardiac Myofibrillar Mg2+-ATPase Activity by Calmidazolium

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Heart Failure, Myocardial Stunning, and Troponin: A Key Regulator of the Cardiac Myofilament

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Clinical and Economic Benefits of Using AUDICOR S3 Detection for Diagnosis and Treatment of Acute Decompensated Heart Failure

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Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

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Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: An update on glucose toxicity

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Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

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Role of O -linked N -acetylglucosamine protein modification in cellular (patho)physiology

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Glucose Metabolism in Cardiac Hypertrophy and Heart Failure

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O-GlcNAc profiling: from proteins to proteomes

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Finding the weakest link – exploring integrin-mediated mechanical molecular pathways

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

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Protein O -GlcNAcylation in diabetes and diabetic complications

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Cracking the O-GlcNAc code in metabolism

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Post-translational modification and regulation of actin

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Cross-talk between Two Essential Nutrient-sensitive Enzymes

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Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca 2+ Control, and SR Ca 2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy

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Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

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Diabetes-associated dysregulation of O -GlcNAcylation in rat cardiac mitochondria

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Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure

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Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc

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O-linked β- N -acetylglucosamine transferase is indispensable in the failing heart

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Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease

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Analytical and Biochemical Perspectives of Protein O-GlcNAcylation

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Roles of O-GlcNAc in chronic diseases of aging

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Regulation of Calcium/Calmodulin-dependent Kinase IV by O-GlcNAc Modification

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ProteinO-GlcNAcylation: a new signaling paradigm for the cardiovascular system

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TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure–function relationships

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New insights: A role forO-GlcNAcylation in diabetic complications

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Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

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O-GlcNAcylation and cardiovascular disease

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Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

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Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle

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AMP-Activated Protein Kinase Phosphorylates Cardiac Troponin I and Alters Contractility of Murine Ventricular Myocytes

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Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes

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Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics

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Myofilament Calcium Sensitivity: Role in Regulation of In vivo Cardiac Contraction and Relaxation

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Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose

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Thick Filament Protein Network, Functions, and Disease Association

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Stress hyperglycemia, cardiac glucotoxicity, and critically ill patient outcomes current clinical and pathophysiological evidence

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Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms

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O-GlcNAcylation, enemy or ally during cardiac hypertrophy development?

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The roles ofO-linked β-N-acetylglucosamine in cardiovascular physiology and disease

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Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications

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Overview

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AMP-activated Protein Kinase Phosphorylates Cardiac Troponin I at Ser-150 to Increase Myofilament Calcium Sensitivity and Blunt PKA-dependent Function

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Opportunities for Therapeutic Modulation of O-GlcNAc

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Divide and Conquer

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Combined Antibody/Lectin Enrichment Identifies Extensive Changes in the O- GlcNAc Sub-proteome upon Oxidative Stress

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Protein O-GlcNAcylation in cardiovascular diseases

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The role of hyperglycaemia in the development of diabetic cardiomyopathy

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Mechanistic Insights Into Nitrite-Induced Cardioprotection Using an Integrated Metabolomic/Proteomic Approach

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Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure

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O-GlcNAc Transferase Inhibitor Synergistically Enhances Doxorubicin-Induced Apoptosis in HepG2 Cells

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Chronic ingestion of a Western diet increases O-linked-β-N-acetylglucosamine (O-GlcNAc) protein modification in the rat heart

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Involvement of O-GlcNAcylation in the Skeletal Muscle Physiology and Physiopathology: Focus on Muscle Metabolism

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Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including α-actinin 4

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Proteome-wide profiling and mapping of post translational modifications in human hearts

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A Global Profile of Reversible and Irreversible Cysteine Redox Post-Translational Modifications During Myocardial Ischemia/Reperfusion Injury and Antioxidant Intervention

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Myocardial glucotoxicity: Mechanisms and potential therapeutic targets

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The continuing evolution of cardiac troponin I biomarker analysis: from protein to proteoform

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Protein O‐GlcNAcylation in the heart

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The role of post‐translational modifications in acute and chronic cardiovascular disease

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Regulation of cardiac O-GlcNAcylation: More than just nutrient availability

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Glycation and Glycosylation in Cardiovascular Remodeling: Focus on Advanced Glycation End Products and O-Linked Glycosylations as Glucose-Related Pathogenetic Factors and Disease Markers

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Cardiac troponins may be irreversibly modified by glycation: novel potential mechanisms of cardiac performance modulation

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Increasing O-GlcNAcylation Level on Organ Culture of Soleus Modulates the Calcium Activation Parameters of Muscle Fibers

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