The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Rotors and the Dynamics of Cardiac Fibrillation
Open accessAbstract
The objective of this article is to present a broad review of the role of cardiac electric rotors and their accompanying spiral waves in the mechanism of cardiac fibrillation. At the outset, we present a brief historical overview regarding reentry and then discuss the basic concepts and terminologies pertaining to rotors and their initiation. Thereafter, the intrinsic properties of rotors and spiral waves, including phase singularities, wavefront curvature, and dominant frequency maps, are discussed. The implications of rotor dynamics for the spatiotemporal organization of fibrillation, independent of the species being studied, are described next. The knowledge gained regarding the role of cardiac structure in the initiation or maintenance of rotors and the ionic bases of spiral waves in the past 2 decades, as well as the significance for drug therapy, is reviewed subsequently. We conclude by examining recent evidence suggesting that rotors are critical in sustaining both atrial and ventricular fibrillation in the human heart and its implications for treatment with radiofrequency ablation.
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Citations
Cites
Atrial Remodeling and Atrial Fibrillation: Mechanisms and Implications
Nattel, S., Burstein, B., & Dobrev, D. (2008) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.107.754564 · Cited by 1,124
Filgueiras-Rama, D., Price, N. F., Martins, R. P., Yamazaki, M., Avula, U. M. R., Kaur, K., Kalifa, J., Ennis, S. R., Hwang, E., Devabhaktuni, V., et al. (2012) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.111.969519 · Cited by 70 · cited 1×
“Recently, using a chronic RA tachypacing model of persistent AF in the sheep, along with continuous cardiac rhythm monitoring by dual implantable devices, we demonstrated that rotors are capable of maintaining cardiac fibrillation in the long-term, even after both structural and electric remodeling have taken place.(8…”
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Cited by
Calkins, H., Hindricks, G., Cappato, R., Kim, Y.-H., Saad, E. B., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, J., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.05.012 · Cited by 2,755
Self-citationMillimetre-scale magnetocardiography of living rats with thoracotomy
Arai, K., Kuwahata, A., Nishitani, D., Fujisaki, I., Matsuki, R., Nishio, Y., Xin, Z., Cao, X., Hatano, Y., Onoda, S., et al. (2022) · Communications Physics · doi:10.1038/s42005-022-00978-0 · Cited by 85
Metadata
- Authors
- Pandit, S. V., & Jalife, J.
- Venue
- Circulation Research
- Published
- 2013-03
- Volume
- 112
- Issue
- 5
- Pages
- 849-862
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2051626126
- Cited by
- 404
- References
- 2
- FWCI
- 24.15
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Pandit, S. V., & Jalife, J. (2013). Rotors and the Dynamics of Cardiac Fibrillation. Circulation Research. https://doi.org/10.1161/circresaha.111.300158
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.