The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
Obesity and Cardiovascular Disease
Abstract
The prevalence of obesity has increased worldwide over the past few decades. In 2013, the prevalence of obesity exceeded the 50% of the adult population in some countries from Oceania, North Africa, and Middle East. Lower but still alarmingly high prevalence was observed in North America (≈30%) and in Western Europe (≈20%). These figures are of serious concern because of the strong link between obesity and disease. In the present review, we summarize the current evidence on the relationship of obesity with cardiovascular disease (CVD), discussing how both the degree and the duration of obesity affect CVD. Although in the general population, obesity and, especially, severe obesity are consistently and strongly related with higher risk of CVD incidence and mortality, the one-size-fits-all approach should not be used with obesity. There are relevant factors largely affecting the CVD prognosis of obese individuals. In this context, we thoroughly discuss important concepts such as the fat-but-fit paradigm, the metabolically healthy but obese (MHO) phenotype and the obesity paradox in patients with CVD. About the MHO phenotype and its CVD prognosis, available data have provided mixed findings, what could be partially because of the adjustment or not for key confounders such as cardiorespiratory fitness, and to the lack of consensus on the MHO definition. In the present review, we propose a scientifically based harmonized definition of MHO, which will hopefully contribute to more comparable data in the future and a better understanding on the MHO subgroup and its CVD prognosis.
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Self-citationForouzanfar, M. H., Afshin, A., Alexander, L. T., Anderson, H. R., Bhutta, Z. A., Biryukov, S., Brauer, M., Burnett, R., Cercy, K., Charlson, F. J., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31679-8 · Cited by 7,698
Bariatric Surgery: A Systematic Review and Meta-analysis
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Extended international (IOTF) body mass index cut‐offs for thinness, overweight and obesity
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An Overview and Update on Obesity and the Obesity Paradox in Cardiovascular Diseases
Elagizi, A., Kachur, S., Lavie, C. J., Carbone, S., Pandey, A., Ortega, F. B., & Milani, R. V. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.07.003 · Cited by 698
Self-citationObesity, kidney dysfunction and hypertension: mechanistic links
Hall, J. E., do Carmo, J. M., da Silva, A. A., Wang, Z., & Hall, M. E. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0145-4 · Cited by 654
Piché, M.-E., Poirier, P., Lemieux, I., & Després, J.-P. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.06.004 · Cited by 558
Executive Function Performance in Obesity and Overweight Individuals: A Meta-Analysis and Review
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Metadata
- Authors
- Ortega, F. B., Lavie, C. J., & Blair, S. N.
- Venue
- Circulation Research
- Published
- 2016-05-27
- Volume
- 118
- Issue
- 11
- Pages
- 1752-1770
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2407467502
- Cited by
- 1,202
- References
- 156
- FWCI
- 74.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ortega, F. B., Lavie, C. J., & Blair, S. N. (2016). Obesity and Cardiovascular Disease. Circulation Research. https://doi.org/10.1161/circresaha.115.306883
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
