The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Cardiac Dyssynchrony Analysis Using Circumferential Versus Longitudinal Strain: Implications for Assessing Cardiac Resynchronization
Open accessAbstract
Background— QRS duration is commonly used to select heart failure patients for cardiac resynchronization therapy (CRT). However, not all patients respond to CRT, and recent data suggest that direct assessments of mechanical dyssynchrony may better predict chronic response. Echo-Doppler methods are being used increasingly, but these principally rely on longitudinal motion (ε ll ). It is unknown whether this analysis yields qualitative and/or quantitative results similar to those based on motion in the predominant muscle-fiber orientation (circumferential; ε cc ). Methods and Results— Both ε ll and ε cc strains were calculated throughout the left ventricle from 3D MR-tagged images for the full cardiac cycle in dogs with cardiac failure and a left bundle conduction delay. Dyssynchrony was assessed from both temporal and regional strain variance analysis. CRT implemented by either biventricular (BiV) or left ventricular–only (LV) pacing enhanced systolic function similarly and correlated with improved dyssynchrony based on ε cc -based metrics. In contrast, longitudinal-based analyses revealed significant resynchronization with BiV but not LV for the overall cycle and correlated poorly with global functional benefit. Furthermore, unlike circumferential analysis, ε ll -based indexes indicated resynchronization in diastole but much less in systole and had a lower dynamic range and higher intrasubject variance. Conclusions— Dyssynchrony assessed by longitudinal motion is less sensitive to dyssynchrony, follows different time courses than those from circumferential motion, and may manifest CRT benefit during specific cardiac phases depending on pacing mode. These results highlight potential limitations to ε ll -based analyses and support further efforts to develop noninvasive synchrony measures based on circumferential deformation.
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Self-citationCardiac Resynchronization in Chronic Heart Failure
Abraham, W. T., Fisher, W. G., Smith, A. L., Delurgio, D. B., Leon, A. R., Loh, E., Kocovic, D. Z., Packer, M., Clavell, A. L., Hayes, D. L., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013168 · Cited by 4,648
CARDIAC RESYNCHRONIZATION IN CHRONIC HEART FAILURE
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St John Sutton, M. G., Plappert, T., Abraham, W. T., Smith, A. L., DeLurgio, D. B., Leon, A. R., Loh, E., Kocovic, D. Z., Fisher, W. G., Ellestad, M., et al. (2003) · Circulation · doi:10.1161/01.cir.0000065226.24159.e9 · Cited by 1,124
Yu, C.-M., Chau, E., Sanderson, J. E., Fan, K., Tang, M.-O., Fung, W.-H., Lin, H., Kong, S.-L., Lam, Y.-M., Hill, M. R. S., et al. (2002) · Circulation · doi:10.1161/hc0402.102623 · Cited by 1,110
Real-Time Strain Rate Imaging of the Left Ventricle by Ultrasound
Heimdal, A., Støylen, A., Torp, H., & Skjærpe, T. (1998) · Journal of the American Society of Echocardiography · doi:10.1016/s0894-7317(98)70151-8 · Cited by 850
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Self-citationCardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchrony
Pitzalis, M. V., Iacoviello, M., Romito, R., Massari, F., Rizzon, B., Luzzi, G., Guida, P., Andriani, A., Mastropasqua, F., & Rizzon, P. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02337-9 · Cited by 716
Yu, C.-M., Fung, J. W.-H., Zhang, Q., Chan, C.-K., Chan, Y.-S., Lin, H., Kum, L. C. C., Kong, S.-L., Zhang, Y., & Sanderson, J. E. (2004) · Circulation · doi:10.1161/01.cir.0000133276.45198.a5 · Cited by 624
Strain and strain rate imaging: a new clinical approach to quantifying regional myocardial function
Sutherland, G. R., Di Salvo, G., Claus, P., D'hooge, J., & Bijnens, B. (2004) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2004.03.027 · Cited by 606
Cited by
Daubert, J.-C., Saxon, L., Adamson, P. B., Auricchio, A., Berger, R. D., Beshai, J. F., Breithard, O., Brignole, M., Cleland, J., DeLurgio, D. B., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2012.07.025 · Cited by 467
Self-citationWhite, J. A., Yee, R., Yuan, X., Krahn, A., Skanes, A., Parker, M., Klein, G., & Drangova, M. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.07.046 · Cited by 386
Metadata
- Authors
- Helm, R. H., Leclercq, C., Faris, O. P., Ozturk, C., McVeigh, E., Lardo, A. C., & Kass, D. A.
- Venue
- Circulation
- Published
- 2005-05-31
- Volume
- 111
- Issue
- 21
- Pages
- 2760-2767
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1972515728
- Cited by
- 275
- References
- 32
- FWCI
- 19.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Cardiac Dyssynchrony Analysis Using Circumferential Versus Longitudinal Strain: Implications for Assessing Cardiac Resynchronization. https://app.cochat.ai/papers/10.1161/circulationaha.104.508457
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- Helm, R. H., Leclercq, C., Faris, O. P., Ozturk, C., McVeigh, E., Lardo, A. C., & Kass, D. A. (2005). Cardiac Dyssynchrony Analysis Using Circumferential Versus Longitudinal Strain: Implications for Assessing Cardiac Resynchronization. Circulation. https://doi.org/10.1161/circulationaha.104.508457
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