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Cited by 522

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Prevalence and Prognostic Significance of Heart Failure Stages: Application of the American College of Cardiology/American Heart Association Heart Failure Staging Criteria in the Community

Open access
Ammar, Khawaja Afzal, Jacobsen, Steven J., Mahoney, Douglas W., Kors, Jan A., Redfield, Margaret M., Burnett, John C., Rodeheffer, Richard J.·2007·Circulation

Abstract

Background— Heart failure (HF) is a progressive disorder associated with frequent morbidity and mortality. An American Heart Association/American College of Cardiology staging classification of HF has been developed to emphasize early detection and prevention. The prevalence of HF stages and their association with mortality are unknown. We sought to estimate HF stage prevalence in the community and to measure the association of HF stages with mortality. Methods and Results— A population-based, cross-sectional, random sample of 2029 Olmsted County, Minnesota, residents aged ≥45 years was identified. Participants were classified by medical record review, symptom questionnaire, physical examination, and echocardiogram as follows: stage 0, healthy; stage A, HF risk factors; stage B, asymptomatic cardiac structural or functional abnormalities; stage C, HF symptoms; and stage D, severe HF. In the cohort, 32% were stage 0, 22% stage A, 34% stage B, 12% stage C, and 0.2% stage D. Mean B-type natriuretic peptide concentrations (in pg/mL) increased by stages: stage 0=26, stage A=32, stage B=53, stage C=137, and stage D=353. Survival at 5 years was 99% in stage 0, 97% in stage A, 96% in stage B, 75% in stage C, and 20% in stage D. Conclusions— The present study provides prevalence estimates and prognostic validation for HF staging in a community cohort. Of note, 56% of adults ≥45 years of age were classified as being in stage A (risk factors) or B (asymptomatic ventricular dysfunction). HF staging underscores the magnitude of the population at risk for progression to overt HF.

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Metadata

Authors
Ammar, K. A., Jacobsen, S. J., Mahoney, D. W., Kors, J. A., Redfield, M. M., Burnett, J. C., & Rodeheffer, R. J.
Venue
Circulation
Published
2007-03-27
Volume
115
Issue
12
Pages
1563-1570
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2033969839
Cited by
522
References
39
FWCI
11.45
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Prevalence and Prognostic Significance of Heart Failure Stages: Application of the American College of Cardiology/American Heart Association Heart Failure Staging Criteria in the Community. https://app.cochat.ai/papers/10.1161/circulationaha.106.666818
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Ammar, K. A., Jacobsen, S. J., Mahoney, D. W., Kors, J. A., Redfield, M. M., Burnett, J. C., & Rodeheffer, R. J. (2007). Prevalence and Prognostic Significance of Heart Failure Stages: Application of the American College of Cardiology/American Heart Association Heart Failure Staging Criteria in the Community. Circulation. https://doi.org/10.1161/circulationaha.106.666818

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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