The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Long-Term Safety and Efficacy of Percutaneous Coronary Intervention With Stenting and Coronary Artery Bypass Surgery for Multivessel Coronary Artery Disease: A Meta-Analysis With 5-Year Patient-Level Data From the ARTS, ERACI-II, MASS-II, and SoS Trials
Open accessAbstract
Background— Randomized trials that studied clinical outcomes after percutaneous coronary intervention (PCI) with bare metal stenting versus coronary artery bypass grafting (CABG) are underpowered to properly assess safety end points like death, stroke, and myocardial infarction. Pooling data from randomized controlled trials increases the statistical power and allows better assessment of the treatment effect in high-risk subgroups. Methods and Results— We performed a pooled analysis of 3051 patients in 4 randomized trials evaluating the relative safety and efficacy of PCI with stenting and CABG at 5 years for the treatment of multivessel coronary artery disease. The primary end point was the composite end point of death, stroke, or myocardial infarction. The secondary end point was the occurrence of major adverse cardiac and cerebrovascular accidents, death, stroke, myocardial infarction, and repeat revascularization. We tested for heterogeneities in treatment effect in patient subgroups. At 5 years, the cumulative incidence of death, myocardial infarction, and stroke was similar in patients randomized to PCI with stenting versus CABG (16.7% versus 16.9%, respectively; hazard ratio, 1.04, 95% confidence interval, 0.86 to 1.27; P =0.69). Repeat revascularization, however, occurred significantly more frequently after PCI than CABG (29.0% versus 7.9%, respectively; hazard ratio, 0.23; 95% confidence interval, 0.18 to 0.29; P <0.001). Major adverse cardiac and cerebrovascular events were significantly higher in the PCI than the CABG group (39.2% versus 23.0%, respectively; hazard ratio, 0.53; 95% confidence interval, 0.45 to 0.61; P <0.001). No heterogeneity of treatment effect was found in the subgroups, including diabetic patients and those presenting with 3-vessel disease. Conclusions— In this pooled analysis of 4 randomized trials, PCI with stenting was associated with a long-term safety profile similar to that of CABG. However, as a result of persistently lower repeat revascularization rates in the CABG patients, overall major adverse cardiac and cerebrovascular event rates were significantly lower in the CABG group at 5 years.
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Cites
Beta blockade during and after myocardial infarction: An overview of the randomized trials
Yusuf, S., Peto, R., Lewis, J., Collins, R., & Sleight, P. (1985) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(85)80003-7 · Cited by 3,205
Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents
Stone, G. W., Moses, J. W., Ellis, S. G., Schofer, J., Dawkins, K. D., Morice, M.-C., Colombo, A., Schampaert, E., Grube, E., Kirtane, A. J., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa067193 · Cited by 1,631
Comparison of Coronary Bypass Surgery with Angioplasty in Patients with Multivessel Disease
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Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis
Stettler, C., Wandel, S., Allemann, S., Kastrati, A., Morice, M. C., Schömig, A., Pfisterer, M. E., Stone, G. W., Leon, M. B., de Lezo, J. S., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61444-5 · Cited by 1,428
Comparison of Coronary-Artery Bypass Surgery and Stenting for the Treatment of Multivessel Disease
Serruys, P. W., Unger, F., Sousa, J. E., Jatene, A., Bonnier, H. J. R. M., Schönberger, J. P. A. M., Buller, N., Bonser, R., van den Brand, M. J. B., van Herwerden, L. A., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200104123441502 · Cited by 1,114
Self-citationAnalysis of 14 Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents
Kastrati, A., Mehilli, J., Pache, J., Kaiser, C., Valgimigli, M., Kelbæk, H., Menichelli, M., Sabaté, M., Suttorp, M. J., Baumgart, D., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa067484 · Cited by 1,006
Long-Term Outcomes of Coronary-Artery Bypass Grafting versus Stent Implantation
Hannan, E. L., Racz, M. J., Walford, G., Jones, R. H., Ryan, T. J., Bennett, E., Culliford, A. T., Isom, O. W., Gold, J. P., & Rose, E. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa040316 · Cited by 664
Serruys, P. W., Ong, A. T. L., van Herwerden, L. A., Sousa, J. E., Jatene, A., Bonnier, J. J. R. M., Schönberger, J. P. M. A., Buller, N., Bonser, R., Disco, C., et al. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.082 · Cited by 608
Self-citationHueb, W., Lopes, N. H., Gersh, B. J., Soares, P., Machado, L. A. C., Jatene, F. B., Oliveira, S. A., & Ramires, J. A. F. (2007) · Circulation · doi:10.1161/circulationaha.106.625475 · Cited by 576
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Cited by
Serruys, P. W., Morice, M.-C., Kappetein, A. P., Colombo, A., Holmes, D. R., Mack, M. J., Ståhle, E., Feldman, T. E., van den Brand, M., Bass, E. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804626 · Cited by 4,331
Self-citationFihn, S. D., Blankenship, J. C., Alexander, K. P., Bittl, J. A., Byrne, J. G., Fletcher, B. J., Fonarow, G. C., Lange, R. A., Levine, G. N., Maddox, T. M., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000095 · Cited by 1,029
Head, S. J., Milojevic, M., Daemen, J., Ahn, J.-M., Boersma, E., Christiansen, E. H., Domanski, M. J., Farkouh, M. E., Flather, M., Fuster, V., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30423-9 · Cited by 734
Self-citationFihn, S. D., Blankenship, J. C., Alexander, K. P., Bittl, J. A., Byrne, J. G., Fletcher, B. J., Fonarow, G. C., Lange, R. A., Levine, G. N., Maddox, T. M., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.07.017 · Cited by 699
Garg, S., & Serruys, P. W. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.007 · Cited by 501
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Metadata
- Authors
- Daemen, J., Boersma, E., Flather, M., Booth, J., Stables, R., Rodriguez, A., Rodriguez-Granillo, G., Hueb, W. A., Lemos, P. A., & Serruys, P. W.
- Venue
- Circulation
- Published
- 2008-09-09
- Volume
- 118
- Issue
- 11
- Pages
- 1146-1154
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2089204790
- Cited by
- 300
- References
- 35
- FWCI
- 34.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Long-Term Safety and Efficacy of Percutaneous Coronary Intervention With Stenting and Coronary Artery Bypass Surgery for Multivessel Coronary Artery Disease: A Meta-Analysis With 5-Year Patient-Level Data From the ARTS, ERACI-II, MASS-II, and SoS Trials. https://app.cochat.ai/papers/10.1161/circulationaha.107.752147
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- Daemen, J., Boersma, E., Flather, M., Booth, J., Stables, R., Rodriguez, A., Rodriguez-Granillo, G., Hueb, W. A., Lemos, P. A., & Serruys, P. W. (2008). Long-Term Safety and Efficacy of Percutaneous Coronary Intervention With Stenting and Coronary Artery Bypass Surgery for Multivessel Coronary Artery Disease: A Meta-Analysis With 5-Year Patient-Level Data From the ARTS, ERACI-II, MASS-II, and SoS Trials. Circulation. https://doi.org/10.1161/circulationaha.107.752147
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