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Cited by 317

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Ten-Year Follow-Up Survival of the Medicine, Angioplasty, or Surgery Study (MASS II): A Randomized Controlled Clinical Trial of 3 Therapeutic Strategies for Multivessel Coronary Artery Disease

Hueb, Whady, Lopes, Neuza, Gersh, Bernard J., Soares, Paulo R., Ribeiro, Expedito E., Pereira, Alexandre C., Favarato, Desiderio, Rocha, Antonio Sérgio C., Hueb, Alexandre C., Ramires, Jose A.F.·2010·Circulation
DOI 10.1161/circulationaha.109.911669
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Abstract

Background— This study compared the 10-year follow-up of percutaneous coronary intervention (PCI), coronary artery surgery (CABG), and medical treatment (MT) in patients with multivessel coronary artery disease, stable angina, and preserved ventricular function. Methods and Results— The primary end points were overall mortality, Q-wave myocardial infarction, or refractory angina that required revascularization. All data were analyzed according to the intention-to-treat principle. At a single institution, 611 patients were randomly assigned to CABG (n=203), PCI (n=205), or MT (n=203). The 10-year survival rates were 74.9% with CABG, 75.1% with PCI, and 69% with MT ( P =0.089). The 10-year rates of myocardial infarction were 10.3% with CABG, 13.3% with PCI, and 20.7% with MT ( P <0.010). The 10-year rates of additional revascularizations were 7.4% with CABG, 41.9% with PCI, and 39.4% with MT ( P <0.001). Relative to the composite end point, Cox regression analysis showed a higher incidence of primary events in MT than in CABG (hazard ratio 2.35, 95% confidence interval 1.78 to 3.11) and in PCI than in CABG (hazard ratio 1.85, 95% confidence interval 1.39 to 2.47). Furthermore, 10-year rates of freedom from angina were 64% with CABG, 59% with PCI, and 43% with MT ( P <0.001). Conclusions— Compared with CABG, MT was associated with a significantly higher incidence of subsequent myocardial infarction, a higher rate of additional revascularization, a higher incidence of cardiac death, and consequently a 2.29-fold increased risk of combined events. PCI was associated with an increased need for further revascularization, a higher incidence of myocardial infarction, and a 1.46-fold increased risk of combined events compared with CABG. Additionally, CABG was better than MT at eliminating anginal symptoms. Clinical Trial Registration Information— URL: http://www.controlled-trials.com. Registration number: ISRCTN66068876.

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Metadata

Authors
Hueb, W., Lopes, N., Gersh, B. J., Soares, P. R., Ribeiro, E. E., Pereira, A. C., Favarato, D., Rocha, A. S. C., Hueb, A. C., & Ramires, J. A. F.
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2010-09-07
Volume
122
Issue
10
Pages
949-957
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/circulationaha.109.911669
OpenAlex
W3037719510
Cited by
317
References
19
FWCI
24.53
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Ten-Year Follow-Up Survival of the Medicine, Angioplasty, or Surgery Study (MASS II): A Randomized Controlled Clinical Trial of 3 Therapeutic Strategies for Multivessel Coronary Artery Disease. https://app.cochat.ai/papers/10.1161/circulationaha.109.911669
The paper
Hueb, W., Lopes, N., Gersh, B. J., Soares, P. R., Ribeiro, E. E., Pereira, A. C., Favarato, D., Rocha, A. S. C., Hueb, A. C., & Ramires, J. A. F. (2010). Ten-Year Follow-Up Survival of the Medicine, Angioplasty, or Surgery Study (MASS II): A Randomized Controlled Clinical Trial of 3 Therapeutic Strategies for Multivessel Coronary Artery Disease. Circulation. https://doi.org/10.1161/circulationaha.109.911669

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.