Standardized Bleeding Definitions for Cardiovascular Clinical Trials: A Consensus Report From the Bleeding Academic Research Consortium

Abstract

HomeCirculationVol. 123, No. 23Standardized Bleeding Definitions for Cardiovascular Clinical Trials Free AccessResearch ArticlePDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplementary MaterialsFree AccessResearch ArticlePDF/EPUBStandardized Bleeding Definitions for Cardiovascular Clinical TrialsA Consensus Report From the Bleeding Academic Research Consortium Roxana Mehran, MD, Sunil V. Rao, MD, Deepak L. Bhatt, MD, MPH, C. Michael Gibson, MS, MD, Adriano Caixeta, MD, PhD, John Eikelboom, MD, MBBS, Sanjay Kaul, MD, Stephen D. Wiviott, MD, Venu Menon, MD, Eugenia Nikolsky, MD, PhD, Victor Serebruany, MD, PhD, Marco Valgimigli, MD, PhD, Pascal Vranckx, MD, David Taggart, MD, PhD, Joseph F. Sabik, MD, Donald E. Cutlip, MD, Mitchell W. Krucoff, MD, E. Magnus Ohman, MD, Philippe Gabriel Steg, MD and Harvey White, MB, ChB, DSc Roxana MehranRoxana Mehran The BARC represents a collaboration of independent academic research organizations (Cardialysis, Rotterdam, the Netherlands; Cardiovascular Research Foundation, New York City, NY; Duke Clinical Research Institute, Durham, NC; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Harvard Clinical Research Institute, Boston, MA; Green Lane Coordinating Centre, Auckland, New Zealand; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland, OH; and PERFUSE, Boston, MA), professional societies (European Society of Cardiology, and Society of Cardiac Angiography and Intervention), federal agencies (the US FDA, National Institutes of Health), and independent expert scientists and consultants (Appendix). Search for more papers by this author , Sunil V. RaoSunil V. Rao The BARC represents a collaboration of independent academic research organizations (Cardialysis, Rotterdam, the Netherlands; Cardiovascular Research Foundation, New York City, NY; Duke Clinical Research Institute, Durham, NC; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Harvard Clinical Research Institute, Boston, MA; Green Lane Coordinating Centre, Auckland, New Zealand; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland, OH; and PERFUSE, Boston, MA), professional societies (European Society of Cardiology, and Society of Cardiac Angiography and Intervention), federal agencies (the US FDA, National Institutes of Health), and independent expert scientists and consultants (Appendix). Search for more papers by this author , Deepak L. BhattDeepak L. Bhatt The BARC represents a collaboration of independent academic research organizations (Cardialysis, Rotterdam, the Netherlands; Cardiovascular Research Foundation, New York City, NY; Duke Clinical Research Institute, Durham, NC; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Harvard Clinical Research Institute, Boston, MA; Green Lane Coordinating Centre, Auckland, New Zealand; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland, OH; and PERFUSE, Boston, MA), professional societies (European Society of Cardiology, and Society of Cardiac Angiography and Intervention), federal agencies (the US FDA, National Institutes of Health), and independent expert scientists and consultants (Appendix). Search for more papers by this author , C. Michael GibsonC. Michael Gibson The BARC represents a collaboration of independent academic research organizations (Cardialysis, Rotterdam, the Netherlands; Cardiovascular Research Foundation, New York City, NY; Duke Clinical Research Institute, Durham, NC; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Harvard Clinical Research Institute, Boston, MA; Green Lane Coordinating Centre, Auckland, New Zealand; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland, OH; and PERFUSE, Boston, MA), professional societies (European Society of Cardiology, and Society of Cardiac Angiography and Intervention), federal agencies (the US FDA, National Institutes of Health), and independent expert scientists and consultants (Appendix). Search for more papers by this author , Adriano CaixetaAdriano Caixeta The BARC represents a collaboration of independent academic research organizations (Cardialysis, Rotterdam, the Netherlands; Cardiovascular Research Foundation, New York City, NY; Duke Clinical Research Institute, Durham, NC; TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Harvard Clinical Research Institute, Boston, MA; Green Lane Coordinating Centre, Auckland, New Zealand; Cleveland Clinic Coordinating Center for Clinical Research, Cleveland, OH; and PERFUSE, Boston, MA), professional societies (European Society of Cardio