The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Is Hypothermia After Cardiac Arrest Effective in Both Shockable and Nonshockable Patients?: Insights From a Large Registry
Open accessAbstract
Background—: Although the level of evidence of improvement is significant in cardiac arrest patients resuscitated from a shockable rhythm (ventricular fibrillation or pulseless ventricular tachycardia [VF/V t ]), the use of therapeutic mild hypothermia (TMH) is more controversial in nonshockable patients (pulseless electric activity or asystole [PEA/asystole]). We therefore assessed the prognostic value of hypothermia for neurological outcome at hospital discharge according to first-recorded cardiac rhythm in a large cohort. Methods and Results—: Between January 2000 and December 2009, data from 1145 consecutive out-of-hospital cardiac arrest patients in whom a successful resuscitation had been achieved were prospectively collected. The association of TMH with a good neurological outcome at hospital discharge (cerebral performance categories level 1 or 2) was quantified by logistic regression analysis. TMH was induced in 457/708 patients (65%) in VF/V t and in 261/437 patients (60%) in PEA/asystole. Overall, 342/1145 patients (30%) reached a favorable outcome (cerebral performance categories level 1 or 2) at hospital discharge, respectively 274/708 (39%) in VF/V t and 68/437 (16%) in PEA/asystole ( P <0.001). After adjustment, in VF/V t patients, TMH was associated with increased odds of good neurological outcome (adjusted odds ratio, 1.90; 95% confidence interval, 1.18 to 3.06) whereas in PEA/asystole patients, TMH was not significantly associated with good neurological outcome (adjusted odds ratio, 0.71; 95% confidence interval, 0.37 to 1.36). Conclusions—: In this large cohort of cardiac arrest patients, hypothermia was independently associated with an improved outcome at hospital discharge in patients presenting with VF/V t . By contrast, TMH was not associated with good outcome in nonshockable patients. Further investigations are needed to clarify this lack of efficiency in PEA/asystole.
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Cites
Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia
Bernard, S. A., Gray, T. W., Buist, M. D., Jones, B. M., Silvester, W., Gutteridge, G., & Smith, K. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa003289 · Cited by 5,401
Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012689 · Cited by 5,220
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191259 · Cited by 3,908
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191261 · Cited by 3,140
Jacobs, I., Nadkarni, V., the ILCOR Task Force on Cardiac Arrest and Cardiopulmonary Resuscitation Outcomes, PARTICIPANTS, C., Bahr, J., Berg, R. A., Billi, J. E., Bossaert, L., Cassan, P., Coovadia, A., et al. (2004) · Circulation · doi:10.1161/01.cir.0000147236.85306.15 · Cited by 2,560
Peberdy, M. A., Callaway, C. W., Neumar, R. W., Geocadin, R. G., Zimmerman, J. L., Donnino, M., Gabrielli, A., Silvers, S. M., Zaritsky, A. L., Merchant, R., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.971002 · Cited by 2,522
Regional Variation in Out-of-Hospital Cardiac Arrest Incidence and Outcome
Nichol, G. (2008) · JAMA · doi:10.1001/jama.300.12.1423 · Cited by 1,961
Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication
Nolan, J. P., Neumar, R. W., Adrie, C., Aibiki, M., Berg, R. A., Böttiger, B. W., Callaway, C., Clark, R. S. B., Geocadin, R. G., Jauch, E. C., et al. (2008) · Resuscitation · doi:10.1016/j.resuscitation.2008.09.017 · Cited by 1,499
Neumar, R. W., Nolan, J. P., Adrie, C., Aibiki, M., Berg, R. A., Böttiger, B. W., Callaway, C., Clark, R. S. B., Geocadin, R. G., Jauch, E. C., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190652 · Cited by 1,436
Writing Group, Nolan, J. P., Morley, P. T., Vanden Hoek, T. L., Hickey, R. W., Members of the Advanced Life Support Task Force, Kloeck, W. G. J., Billi, J., Böttiger, B. W., Morley, P. T., et al. (2003) · Circulation · doi:10.1161/01.cir.0000079019.02601.90 · Cited by 1,107
Self-citation
Cited by
Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest
Nielsen, N., Wetterslev, J., Cronberg, T., Erlinge, D., Gasche, Y., Hassager, C., Horn, J., Hovdenes, J., Kjaergaard, J., Kuiper, M., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1310519 · Cited by 2,766
Callaway, C. W., Donnino, M. W., Fink, E. L., Geocadin, R. G., Golan, E., Kern, K. B., Leary, M., Meurer, W. J., Peberdy, M. A., Thompson, T. M., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000262 · Cited by 1,241
Nolan, J. P., Soar, J., Cariou, A., Cronberg, T., Moulaert, V. R. M., Deakin, C. D., Bottiger, B. W., Friberg, H., Sunde, K., & Sandroni, C. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2015.07.018 · Cited by 1,116
Self-citationLemiale, V., Dumas, F., Mongardon, N., Giovanetti, O., Charpentier, J., Chiche, J.-D., Carli, P., Mira, J.-P., Nolan, J., & Cariou, A. (2013) · Intensive Care Medicine · doi:10.1007/s00134-013-3043-4 · Cited by 720
Self-citationMaupain, C., Bougouin, W., Lamhaut, L., Deye, N., Diehl, J.-L., Geri, G., Perier, M.-C., Beganton, F., Marijon, E., Jouven, X., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv556 · Cited by 351
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Metadata
- Authors
- Dumas, F., Grimaldi, D., Zuber, B., Fichet, J., Charpentier, J., Pène, F., Vivien, B., Varenne, O., Carli, P., Jouven, X., Empana, J.-P., & Cariou, A.
- Venue
- Circulation
- Published
- 2011-03
- Volume
- 123
- Issue
- 8
- Pages
- 877-886
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2023125079
- Cited by
- 296
- References
- 24
- FWCI
- 45.76
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Dumas, F., Grimaldi, D., Zuber, B., Fichet, J., Charpentier, J., Pène, F., Vivien, B., Varenne, O., Carli, P., Jouven, X., Empana, J.-P., & Cariou, A. (2011). Is Hypothermia After Cardiac Arrest Effective in Both Shockable and Nonshockable Patients?: Insights From a Large Registry. Circulation. https://doi.org/10.1161/circulationaha.110.987347
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