The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Timing, Predictive Factors, and Prognostic Value of Cerebrovascular Events in a Large Cohort of Patients Undergoing Transcatheter Aortic Valve Implantation
Abstract
Background—: The objective of this study was to evaluate the timing, predictive factors, and prognostic value of cerebrovascular events (CVEs) after transcatheter aortic valve implantation. Methods and Results—: The study included 1061 consecutive patients who underwent transcatheter aortic valve implantation with a balloon-expandable (64%) or self-expandable (36%) valve. CVEs were classified as acute (≤24 hours), subacute (1–30 days), or late (>30 days). CVEs occurred in 54 patients (5.1%; stroke, 4.2%) within 30 days after transcatheter aortic valve implantation (acute in 54% of cases). The predictors of acute CVEs were balloon postdilation of the valve prosthesis (odds ratio, 2.46; 95% confidence interval,1.07–5.67) and valve dislodgment/embolization (odds ratio, 4.36; 95% CI, 1.21–15.69); new-onset atrial fibrillation (odds ratio, 2.76; 95% CI, 1.11–6.83) was a predictor of subacute CVEs. Late CVEs occurred in 35 patients (3.3%; stroke, 2.1%) at a median follow-up of 12 months (3–23 months). The predictors of late CVEs were chronic atrial fibrillation (2.84; 95% CI, 1.46–5.53), peripheral vascular disease (hazard ratio, 2.02; 95% CI, 1.02–3.97), and prior cerebrovascular disease (hazard ratio, 2.04; 95% CI, 1.01–4.15). Major stroke was associated with 30-day (odds ratio, 7.43; 95% CI, 2.45–22.53) and late (hazard ratio, 1.75; 95% CI, 1.01–3.04) mortality. Conclusions—: In a large cohort of patients undergoing transcatheter aortic valve implantation, the rates of acute and subacute CVEs were 2.7% and 2.4%, respectively. While balloon postdilation and valve dislodgment/embolization were the predictors of acute CVEs, new-onset atrial fibrillation determined a higher risk for subacute events. Late events were determined mainly by a history of chronic atrial fibrillation and peripheral and cerebrovascular disease. The occurrence of major stroke was associated with increased early and late mortality. These results provide important insights for the implementation of preventive measures for CVEs after transcatheter aortic valve implantation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
Patel, M. R., Mahaffey, K. W., Garg, J., Pan, G., Singer, D. E., Hacke, W., Breithardt, G., Halperin, J. L., Hankey, G. J., Piccini, J. P., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1009638 · Cited by 9,430
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Leon, M. B., Smith, C. R., Mack, M., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1008232 · Cited by 7,205
Self-citationTranscatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Smith, C. R., Leon, M. B., Mack, M. J., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103510 · Cited by 6,345
Self-citationRegistry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Gilard, M., Eltchaninoff, H., Iung, B., Donzeau-Gouge, P., Chevreul, K., Fajadet, J., Leprince, P., Leguerrier, A., Lievre, M., Prat, A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1114705 · Cited by 1,228
Leon, M. B., Piazza, N., Nikolsky, E., Blackstone, E. H., Cutlip, D. E., Kappetein, A. P., Krucoff, M. W., Mack, M., Mehran, R., Miller, C., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehq406 · Cited by 1,219
Self-citationTamburino, C., Capodanno, D., Ramondo, A., Petronio, A. S., Ettori, F., Santoro, G., Klugmann, S., Bedogni, F., Maisano, F., Marzocchi, A., et al. (2011) · Circulation · doi:10.1161/circulationaha.110.946533 · Cited by 1,124
Rodés-Cabau, J., Webb, J. G., Cheung, A., Ye, J., Dumont, E., Feindel, C. M., Osten, M., Natarajan, M. K., Velianou, J. L., Martucci, G., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.12.014 · Cited by 974
Self-citationMoat, N. E., Ludman, P., de Belder, M. A., Bridgewater, B., Cunningham, A. D., Young, C. P., Thomas, M., Kovac, J., Spyt, T., MacCarthy, P. A., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.050 · Cited by 884
Thomas, M., Schymik, G., Walther, T., Himbert, D., Lefèvre, T., Treede, H., Eggebrecht, H., Rubino, P., Michev, I., Lange, R., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.907402 · Cited by 875
Standardized Endpoint Definitions for Transcatheter Aortic Valve Implantation Clinical Trials
Leon, M. B., Piazza, N., Nikolsky, E., Blackstone, E. H., Cutlip, D. E., Kappetein, A. P., Krucoff, M. W., Mack, M., Mehran, R., Miller, C., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.12.005 · Cited by 733
Self-citation
Cited by
Rodés-Cabau, J., Masson, J.-B., Welsh, R. C., Garcia del Blanco, B., Pelletier, M., Webb, J. G., Al-Qoofi, F., Généreux, P., Maluenda, G., Thoenes, M., et al. (2017) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2017.04.014 · Cited by 331
Self-citationRodés-Cabau, J., Pibarot, P., Suri, R. M., Kodali, S., Thourani, V. H., Szeto, W. Y., Svensson, L. G., Dumont, E., Xu, K., Hahn, R. T., et al. (2014) · Circulation: Cardiovascular Interventions · doi:10.1161/circinterventions.114.001681 · Cited by 130
Self-citation
Metadata
- Authors
- Nombela-Franco, L., Webb, J. G., de Jaegere, P. P., Toggweiler, S., Nuis, R.-J., Dager, A. E., Amat-Santos, I. J., Cheung, A., Ye, J., Binder, R. K., van der Boon, R. M., Van Mieghem, N., Benitez, L. M., Pérez, S., Lopez, J., San Roman, J. A., Doyle, D., DeLarochellière, R., Urena, M., Leipsic, J., Dumont, E., & Rodés-Cabau, J.
- Venue
- Circulation
- Published
- 2012-12-18
- Volume
- 126
- Issue
- 25
- Pages
- 3041-3053
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2097310220
- Cited by
- 422
- References
- 38
- FWCI
- 17.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Timing, Predictive Factors, and Prognostic Value of Cerebrovascular Events in a Large Cohort of Patients Undergoing Transcatheter Aortic Valve Implantation. https://app.cochat.ai/papers/10.1161/circulationaha.112.110981
- The paper
- Nombela-Franco, L., Webb, J. G., de Jaegere, P. P., Toggweiler, S., Nuis, R.-J., Dager, A. E., Amat-Santos, I. J., Cheung, A., Ye, J., Binder, R. K., van der Boon, R. M., Van Mieghem, N., Benitez, L. M., Pérez, S., Lopez, J., San Roman, J. A., Doyle, D., DeLarochellière, R., Urena, M., . . . Rodés-Cabau, J. (2012). Timing, Predictive Factors, and Prognostic Value of Cerebrovascular Events in a Large Cohort of Patients Undergoing Transcatheter Aortic Valve Implantation. Circulation. https://doi.org/10.1161/circulationaha.112.110981
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
