The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Impact of Preoperative Moderate/Severe Mitral Regurgitation on 2-Year Outcome After Transcatheter and Surgical Aortic Valve Replacement: Insight From the Placement of Aortic Transcatheter Valve (PARTNER) Trial Cohort A
Open accessAbstract
Background—: The effect of preoperative mitral regurgitation (MR) on clinical outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) is controversial. This study sought to examine the impact of moderate and severe MR on outcomes after TAVR and surgical aortic valve replacement (SAVR). Methods and Results—: Data were drawn from the randomized Placement of Aortic Transcatheter Valve (PARTNER) Trial cohort A patients with severe, symptomatic aortic stenosis undergoing either TAVR (n=331) or SAVR (n=299). Both TAVR and SAVR patients were dichotomized according to the degree of preoperative MR (moderate/severe versus none/mild). At baseline, moderate or severe MR was reported in 65 TAVR patients (19.6%) and 63 SAVR patients (21.2%). At 30 days, among survivors who had isolated SAVR/TAVR, moderate/severe MR had improved in 25 SAVR patients (69.4%) and 30 TAVR patients (57.7%), was unchanged in 10 SAVR patients (27.8%) and 19 TAVR patients (36.5%), and worsened in 1 SAVR patient (2.8%) and 4 TAVR patients (5.8%; all P =NS). Mortality at 2 years was higher in SAVR patients with moderate or severe MR than in those with mild or less MR (49.8% versus 28.1%; adjusted hazard ratio, 1.73; 95% confidence interval, 1.01–2.96; P =0.04). In contrast, MR severity at baseline did not affect mortality in TAVR patients (37.0% versus 32.7%, moderate/severe versus none/mild; hazard ratio, 1.14; 95% confidence interval, 0.72–1.78; P =0.58; P for interaction=0.05). Conclusions—: Both TAVR and SAVR were associated with a significant early improvement in MR in survivors. However, moderate or severe MR at baseline was associated with increased 2-year mortality after SAVR but not after TAVR. TAVR may be a reasonable option in selected patients with combined aortic and mitral valve disease. Clinical Trial Registration—: URL: http://www.clinicaltrials.gov . Unique identifier: NCT00530894.
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Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Leon, M. B., Smith, C. R., Mack, M., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1008232 · Cited by 7,205
Self-citationTranscatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Smith, C. R., Leon, M. B., Mack, M. J., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103510 · Cited by 6,345
Self-citationBurden of valvular heart diseases: a population-based study
Nkomo, V. T., Gardin, J. M., Skelton, T. N., Gottdiener, J. S., Scott, C. G., & Enriquez-Sarano, M. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69208-8 · Cited by 4,881
Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Gilard, M., Eltchaninoff, H., Iung, B., Donzeau-Gouge, P., Chevreul, K., Fajadet, J., Leprince, P., Leguerrier, A., Lievre, M., Prat, A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1114705 · Cited by 1,228
Transcatheter Aortic Valve Replacement
Toggweiler, S., Boone, R. H., Rodés-Cabau, J., Humphries, K. H., Lee, M., Nombela-Franco, L., Bagur, R., Willson, A. B., Binder, R. K., Gurvitch, R., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.02.020 · Cited by 215
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Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000923 · Cited by 3,686
Otto, C. M., Kumbhani, D. J., Alexander, K. P., Calhoon, J. H., Desai, M. Y., Kaul, S., Lee, J. C., Ruiz, C. E., & Vassileva, C. M. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.12.006 · Cited by 512
2020 ACC/AHA guideline for the management of patients with valvular heart disease
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2021.04.002 · Cited by 279
Nicoara, A., Skubas, N., Ad, N., Finley, A., Hahn, R. T., Mahmood, F., Mankad, S., Nyman, C. B., Pagani, F., Porter, T. R., et al. (2020) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2020.03.002 · Cited by 264
Self-citationFutility, Benefit, and Transcatheter Aortic Valve Replacement
Lindman, B. R., Alexander, K. P., O'Gara, P. T., & Afilalo, J. (2014) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2014.01.167 · Cited by 222
Metadata
- Authors
- Barbanti, M., Webb, J. G., Hahn, R. T., Feldman, T., Boone, R. H., Smith, C. R., Kodali, S., Zajarias, A., Thompson, C. R., Green, P., Babaliaros, V., Makkar, R. R., Szeto, W. Y., Douglas, P. S., McAndrew, T., Hueter, I., Miller, D. C., & Leon, M. B.
- Venue
- Circulation
- Published
- 2013-12
- Volume
- 128
- Issue
- 25
- Pages
- 2776-2784
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2139645303
- Cited by
- 171
- References
- 5
- FWCI
- 8.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Impact of Preoperative Moderate/Severe Mitral Regurgitation on 2-Year Outcome After Transcatheter and Surgical Aortic Valve Replacement: Insight From the Placement of Aortic Transcatheter Valve (PARTNER) Trial Cohort A. https://app.cochat.ai/papers/10.1161/circulationaha.113.003885
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- Barbanti, M., Webb, J. G., Hahn, R. T., Feldman, T., Boone, R. H., Smith, C. R., Kodali, S., Zajarias, A., Thompson, C. R., Green, P., Babaliaros, V., Makkar, R. R., Szeto, W. Y., Douglas, P. S., McAndrew, T., Hueter, I., Miller, D. C., & Leon, M. B. (2013). Impact of Preoperative Moderate/Severe Mitral Regurgitation on 2-Year Outcome After Transcatheter and Surgical Aortic Valve Replacement: Insight From the Placement of Aortic Transcatheter Valve (PARTNER) Trial Cohort A. Circulation. https://doi.org/10.1161/circulationaha.113.003885
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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