Futility, Benefit, and Transcatheter Aortic Valve Replacement
Open accessAbstract
Transcatheter aortic valve replacement (TAVR) is a transformative innovation that provides treatment for high or prohibitive surgical risk patients with symptomatic severe aortic stenosis who either were previously not referred for or were denied operative intervention. Trials have demonstrated improvements in survival and symptoms after TAVR versus medical therapy; however, there remains a sizable group of patients who die or lack improvement in quality of life soon after TAVR. This raises important questions about the need to identify and acknowledge the possibility of futility in some patients considered for TAVR. In this very elderly population, a number of factors in addition to traditional risk stratification need to be considered including multimorbidity, disability, frailty, and cognition in order to assess the anticipated benefit of TAVR. Consideration by a multidisciplinary heart valve team with broad areas of expertise is critical for assessing likely benefit from TAVR. Moreover, these complicated decisions should take place with clear communication around desired health outcomes on behalf of the patient and provider. The decision that treatment with TAVR is futile should include alternative plans to optimize the patient's health state or, in some cases, discussions related to end-of-life care. We review issues to be considered when making and communicating these difficult decisions.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Because patients who develop severe aortic stenosis are usually older adults, their symptoms may also result in part from normal aging, numerous comorbidities or frailty.
“However, because patients who develop severe AS are usually older adults, these symptoms may also result, in part, from normal aging, numerous comorbidities or frailty202.”
From Calcific aortic stenosis (2016) · cites this paper as [202]
The Introduction’s “Anticipated Benefit of TAVR” section distinguishes patients whose main medical problem can be ascribed to severe AS, and “Geriatric Risk Stratification” describes comorbidities and frailty as prevalent in TAVR patients. These passages support the possibility that problems other than AS contribute to patients’ condition, but they do not specifically attribute the symptoms to normal aging or establish that frailty causes those symptoms. (LLM, conf=0.80)
Experimental — accuracy not yet measuredGiven the high prevalence of frailty and disability in this patient population, the relationship between valvular stenosis and overall quality of life is complex and variable.
“Given the high prevalence of frailty and disability in this patient population, the relationship between valvular stenosis and overall quality of life is also complex and variable.202”
From Calcific aortic stenosis (2016) · cites this paper as [202]
Experimental — accuracy not yet measuredIn general, TAVR is associated with a survival advantage compared with conservative management without aortic valve replacement.
“Although, in general, TAVR is associated with a survival advantage compared to conservative (no AVR) management”
From Calcific aortic stenosis (2016) · cites this paper as [202]
Aortic valve replacement is indicated in patients with severe symptomatic aortic stenosis both to increase life expectancy and to improve symptoms and quality of life.
“AVR is indicated in patients with severe symptomatic AS both to increase life expectancy and improve symptoms and quality of life3;4;199;202;252;253.”
From Calcific aortic stenosis (2016) · cites this paper as [202]
A sizable subgroup dies soon after TAVR or does not experience improved quality of life, suggesting potential futility of TAVR in some patients.
“there is a sizable sub-group that dies soon after TAVR or does not experience an improvement in quality of life, suggesting potential futility of TAVR in some patients201;202;220;244;245.”
From Calcific aortic stenosis (2016) · cites this paper as [202]
When uncertainty exists whether a patient will benefit clinically from valve replacement because of markedly depressed LV function or concomitant oxygen-dependent lung disease or other factors, balloon aortic valvuloplasty may have diagnostic utility.
“When there is uncertainty whether a patient will benefit clinically from valve replacement owing to markedly depressed LV function or concomitant oxygen dependent lung disease or other factors, a BAV may have diagnostic utility to determine whether valve replacement is appropriate202.”
From Calcific aortic stenosis (2016) · cites this paper as [202]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907 · see citing works
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Leon, M. B., Smith, C. R., Mack, M., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1008232 · Cited by 7,205 · see citing works
Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Smith, C. R., Leon, M. B., Mack, M. J., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103510 · Cited by 6,345 · see citing works
Charles, C., Gafni, A., & Whelan, T. (1997) · Social Science & Medicine · doi:10.1016/s0277-9536(96)00221-3 · Cited by 4,137 · cited 1× · see citing works
“Shared decision-making requires both patient and provider share information, work toward a consensus, and reach agreement on the course of action (55).”
BackgroundFried, L. P., Ferrucci, L., Darer, J., Williamson, J. D., & Anderson, G. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.3.m255 · Cited by 4,032 · see citing works
Guidelines on the management of valvular heart disease (version 2012)
Authors/Task Force Members, Vahanian, A., Alfieri, O., Andreotti, F., Antunes, M. J., Barón-Esquivias, G., Baumgartner, H., Borger, M. A., Carrel, T. P., De Bonis, M., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs109 · Cited by 3,559 · see citing works
Percutaneous Transcatheter Implantation of an Aortic Valve Prosthesis for Calcific Aortic Stenosis
Cribier, A. G., Eltchaninoff, H., Bash, A., Borenstein, N., Tron, C., Bauer, F., Dérumeaux, G., Anselme, F., Laborde, F., & Leon, M. B. (2002) · Circulation · doi:10.1161/01.cir.0000047200.36165.b8 · Cited by 3,169 · see citing works
Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement
Kodali, S., Williams, M. R., Smith, C. R., Svensson, L. G., Webb, J. G., Makkar, R., Fontana, G. P., Dewey, T. M., Thourani, V. H., Pichard, A. D., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200384 · Cited by 2,276 · see citing works
Abellan Van Kan, G., Rolland, Y., Andrieu, S., Bauer, J., Beauchet, O., Bonnefoy, M., Cesari, M., Donini, L. M., Gillette-Guyonnet, S., Inzitari, M., et al. (2009) · The Journal of nutrition, health and aging · doi:10.1007/s12603-009-0246-z · Cited by 2,003 · see citing works
Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis
Makkar, R., Fontana, G. P., Jilaihawi, H., Kapadia, S. R., Pichard, A. D., Douglas, P. S., Thourani, V. H., Babaliaros, V. C., Webb, J. G., Herrmann, H. C., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1202277 · Cited by 1,341 · see citing works
Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Gilard, M., Eltchaninoff, H., Iung, B., Donzeau-Gouge, P., Chevreul, K., Fajadet, J., Leprince, P., Leguerrier, A., Lievre, M., Prat, A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1114705 · Cited by 1,228 · see citing works
Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies
Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D. B., Hummel, S., Karunananthan, S., & Wolfson, C. (2007) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/62.7.731 · Cited by 1,134 · see citing works
Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery?
Iung, B., Cachier, A., Baron, G., Messika-Zeitoun, D., Delahaye, F., Tornos, P., Gohlke-Bärwolf, C., Boersma, E., Ravaud, P., & Vahanian, A. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi471 · Cited by 1,108 · see citing works
Fried, L. P. (2001) · Journals of Gerontology Series A-biological Sciences and Medical Sciences · Cited by 1,103 · see citing works
Rodés‐Cabau, J., Webb, J. G., Cheung, A. W., Ye, J., Dumont, É., Feindel, C. M., Osten, M., Natarajan, M. K., Velianou, J. L., Martucci, G. J., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.12.014 · Cited by 970 · see citing works
Moat, N. E., Ludman, P., de Belder, M. A., Bridgewater, B., Cunningham, A. D., Young, C. P., Thomas, M., Kovac, J., Spyt, T., MacCarthy, P. A., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.050 · Cited by 884 · see citing works
2012 ACCF/AATS/SCAI/STS Expert Consensus Document on Transcatheter Aortic Valve Replacement
Holmes, D. R., Mack, M. J., Kaul, S., Agnihotri, A. K., Alexander, K. P., Bailey, S. R., Calhoon, J., Carabello, B. A., Desai, M. Y., Edwards, F. H., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.01.001 · Cited by 747 · see citing works
Self-citationAfilalo, J., Eisenberg, M. J., Morin, J.-F., Bergman, H., Monette, J., Noiseux, N., Perrault, L. P., Alexander, K. P., Langlois, Y., Dendukuri, N., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.039 · Cited by 746 · see citing works
Self-citationImpact of Myocardial Fibrosis in Patients With Symptomatic Severe Aortic Stenosis
Weidemann, F., Herrmann, S., Störk, S., Niemann, M., Frantz, S., Lange, V., Beer, M., Gattenlöhner, S., Voelker, W., Ertl, G., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.847772 · Cited by 706 · see citing works
Role of Frailty in Patients With Cardiovascular Disease
Afilalo, J., Karunananthan, S., Eisenberg, M. J., Alexander, K. P., & Bergman, H. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.01.375 · Cited by 616 · see citing works
Self-citationThe effect of aortic valve replacement on survival.
Schwarz, F., Baumann, P., Manthey, J., Hoffmann, M., Schuler, G., Mehmel, H. C., Schmitz, W., & Kübler, W. (1982) · Circulation · doi:10.1161/01.cir.66.5.1105 · Cited by 584 · see citing works
Thomas, M., Schymik, G., Walther, T., Himbert, D., Lefèvre, T., Treede, H., Eggebrecht, H., Rubino, P., Colombo, A., Lange, R., et al. (2011) · Circulation · doi:10.1161/circulationaha.110.001545 · Cited by 525 · see citing works
Green, P., Woglom, A. E., Genereux, P., Daneault, B., Paradis, J.-M., Schnell, S., Hawkey, M., Maurer, M. S., Kirtane, A. J., Kodali, S., et al. (2012) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2012.06.011 · Cited by 473 · see citing works
Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Gilard, M., Eltchaninoff, H., Iung, B., Donzeau‐Gouge, P., Chevreul, K., Fajadet, J. C., Leprince, P. N., Leguerrier, A., Lièvre, M. M., Prat, A. G., et al. (2013) · Survey of Anesthesiology · doi:10.1097/01.sa.0000426523.25196.4e · Cited by 454 · see citing works
Afilalo, J., Mottillo, S., Eisenberg, M. J., Alexander, K. P., Noiseux, N., Perrault, L. P., Morin, J., Langlois, Y., Ohayon, S. M., Monette, J., et al. (2012) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.111.963157 · Cited by 452 · see citing works
Self-citationHerrmann, H. C., Pibarot, P., Hueter, I., Gertz, Z. M., Stewart, W. J., Kapadia, S., Tuzcu, E. M., Babaliaros, V., Thourani, V., Szeto, W. Y., et al. (2013) · Circulation · doi:10.1161/circulationaha.112.001290 · Cited by 433 · see citing works
Palliative Care in Congestive Heart Failure
Goodlin, S. J. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.02.078 · Cited by 370 · see citing works
Tribouilloy, C., Lévy, F., Rusinaru, D., Guéret, P., Petit-Eisenmann, H., Baleynaud, S., Jobic, Y., Adams, C., Lelong, B., Pasquet, A., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.02.026 · Cited by 366 · see citing works
Dumurgier, J., Elbaz, A., Ducimetiere, P., Tavernier, B., Alperovitch, A., & Tzourio, C. (2009) · BMJ · doi:10.1136/bmj.b4460 · Cited by 344 · see citing works
Comprehensive assessment of frailty for elderly high-risk patients undergoing cardiac surgery☆
Sündermann, S., Dademasch, A., Praetorius, J., Kempfert, J., Dewey, T. M., Falk, V., Mohr, F., & Walther, T. (2010) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2010.04.013 · Cited by 342 · see citing works
Stortecky, S., Schoenenberger, A. W., Moser, A., Kalesan, B., Jüni, P., Carrel, T., Bischoff, S., Schoenenberger, C.-M., Stuck, A. E., Windecker, S., et al. (2012) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2012.02.012 · Cited by 332 · see citing works
Medical Futility in End-of-Life Care: Report of the Council on Ethical and Judicial Affairs
American Medical Association Council on Ethical and Judician Affairs (1999) · JAMA · doi:10.1001/jama.281.10.937 · Cited by 330 · see citing works
Bach, D. S., Siao, D., Girard, S. E., Duvernoy, C., McCallister, B. D., & Gualano, S. K. (2009) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.109.848259 · Cited by 327 · see citing works
Reynolds, M. R., Magnuson, E. A., Lei, Y., Leon, M. B., Smith, C. R., Svensson, L. G., Webb, J. G., Babaliaros, V. C., Bowers, B. S., Fearon, W. F., et al. (2011) · Circulation · doi:10.1161/circulationaha.111.040022 · Cited by 318 · see citing works
Current State of Research on Decision-Making Competence of Cognitively Impaired Elderly Persons
Kim, S. Y. H., Karlawish, J. H., & Caine, E. D. (2002) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200203000-00006 · Cited by 314 · see citing works
American Geriatrics Society Expert Panel on the Care of Older Adults with Multimorbidity (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2012.04187.x · Cited by 309 · see citing works
Sinning, J., Ghanem, A., Steinhäuser, H., Adenauer, V., Hammerstingl, C., Nickenig, G., & Werner, N. (2010) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2010.09.009 · Cited by 302 · see citing works
Schoenenberger, A. W., Stortecky, S., Neumann, S., Moser, A., Juni, P., Carrel, T., Huber, C., Gandon, M., Bischoff, S., Schoenenberger, C.-M., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs304 · Cited by 299 · see citing works
Reynolds, M. R., Magnuson, E. A., Wang, K., Thourani, V. H., Williams, M., Zajarias, A., Rihal, C. S., Brown, D. L., Smith, C. R., Leon, M. B., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.03.075 · Cited by 295 · see citing works
Aortic Valve Replacement for Low-Flow/Low-Gradient Aortic Stenosis
Levy, F., Laurent, M., Monin, J. L., Maillet, J. M., Pasquet, A., Le Tourneau, T., Petit-Eisenmann, H., Gori, M., Jobic, Y., Bauer, F., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.10.067 · Cited by 279 · see citing works
The Heart Team of Cardiovascular Care
Holmes, D. R., Rich, J. B., Zoghbi, W. A., & Mack, M. J. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.08.1034 · Cited by 251 · see citing works
Withholding and Withdrawing Life-sustaining Therapy
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-115-6-478 · Cited by 242 · see citing works
Transcatheter Aortic Valve Replacement
Toggweiler, S., Boone, R. H., Rodés-Cabau, J., Humphries, K. H., Lee, M., Nombela-Franco, L., Bagur, R., Willson, A. B., Binder, R. K., Gurvitch, R., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.02.020 · Cited by 215 · see citing works
2012 ACCF/AATS/SCAI/STS Expert Consensus Document on Transcatheter Aortic Valve Replacement
Holmes, D. R., Mack, M. J., Kaul, S., Agnihotri, A. K., Alexander, K. P., Bailey, S. R., Calhoon, J., Carabello, B. A., Desai, M. Y., Edwards, F. H., et al. (2012) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.24351 · Cited by 199 · see citing works
Self-citationVen, F. L., Freeman, M., Webb, J. G., Clavel, M.-A. A., Wheeler, M., Dumont, É., Thompson, C., Larochellière, R. D., Moss, R., Doyle, D. J., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.044 · Cited by 187 · see citing works
Arnold, S. V., Spertus, J. A., Lei, Y., Allen, K. B., Chhatriwalla, A. K., Leon, M. B., Smith, C. R., Reynolds, M. R., Webb, J. G., Svensson, L. G., et al. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.112.970053 · Cited by 182 · see citing works
Current Management of Calcific Aortic Stenosis
Lindman, B. R., Bonow, R. O., & Otto, C. M. (2013) · Circulation Research · doi:10.1161/circresaha.111.300084 · Cited by 175 · see citing works
Self-citationBarbanti, M., Webb, J. G., Hahn, R. T., Feldman, T. E., Boone, R. H., Smith, C. R., Kodali, S., Zajarías, A., Thompson, C., Green, P., et al. (2013) · Circulation · doi:10.1161/circulationaha.113.003885 · Cited by 172 · see citing works
Melby, S. J., Moon, M. R., Lindman, B. R., Bailey, M. S., Hill, L. L., & Damiano, R. J. (2011) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2011.02.028 · Cited by 169 · see citing works
Self-citationPilotto, A., Addante, F., Franceschi, M., Leandro, G., Rengo, G., D'Ambrosio, P., Longo, M. G., Rengo, F., Pellegrini, F., Dallapiccola, B., et al. (2009) · Circulation Heart Failure · doi:10.1161/circheartfailure.109.865022 · Cited by 158 · see citing works
Bedogni, F., Latib, A., MARCO, F. D., Agnifili, M., Oreglia, J., Pizzocri, S., Latini, R. A., Lanotte, S., Petronio, A. S., Carlo, M. D., et al. (2013) · Circulation · doi:10.1161/circulationaha.113.001822 · Cited by 140 · see citing works
Hamel, M. B., Lynn, J., Teno, J. M., Covinsky, K. E., Wu, A. W., Galanos, A. N., Desbiens, N. A., & Phillips, R. S. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb03129.x · Cited by 119 · see citing works
Durand, É., Borz, B., Godin, M., Tron, C., Litzler, P., Bessou, J., Dacher, J., Bauer, F., Cribier, A. G., & Eltchaninoff, H. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.11.056 · Cited by 114 · see citing works
How to Define a Poor Outcome After Transcatheter Aortic Valve Replacement
Arnold, S. V., Spertus, J. A., Lei, Y., Green, P., Kirtane, A. J., Kapadia, S. R., Thourani, V. H., Herrmann, H. C., Beohar, N., Zajarías, A., et al. (2013) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.113.000354 · Cited by 114 · see citing works
Dvir, D., Waksman, R., Barbash, I. M., Kodali, S. K., Svensson, L. G., Tuzcu, E. M., Xu, K., Minha, S., Alu, M. C., Szeto, W. Y., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.024 · Cited by 112 · see citing works
Palliative Care and Hospice in Advanced Heart Failure
Lemond, L. M., & Allen, L. A. (2011) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2011.03.012 · Cited by 109 · see citing works
Hamel, M. B., Lynn, J., Teno, J. M., Covinsky, K. E., Wu, A. W., Galanos, A. N., Desbiens, N. A., & Phillips, R. S. (2017) · Routledge eBooks · doi:10.4324/9781315240046-31 · Cited by 109 · see citing works
End-of-life preferences of elderly patients with chronic heart failure
Rocca, H. B., Rickenbacher, P. R., Muzzarelli, S., Schindler, R., Maeder, M. T., Jeker, U., Kiowski, W., Leventhal, M., Pfister, O., Osswald, S., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr404 · Cited by 106 · see citing works
Barbanti, M., Binder, R. K., Dvir, D., Tan, J., Freeman, M., Thompson, C., Cheung, A. W., Wood, D. A., Leipsic, J. A., & Webb, J. G. (2014) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.25512 · Cited by 101 · see citing works
Holmes, D. R., & Mack, M. J. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.05.007 · Cited by 95 · see citing works
Life‐Sustaining Treatment and Assisted Death Choices in Depressed Older Patients
Blank, K., Robison, J. T., Doherty, E., Prigerson, H. G., Duffy, J. D., & Schwartz, H. I. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.49036.x · Cited by 74 · see citing works
Restricting Symptoms in the Last Year of Life
Chaudhry, S. I., Murphy, T. E., Gahbauer, E. A., Sussman, L. S., Allore, H. G., & Gill, T. M. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.8732 · Cited by 70 · see citing works
Systematic Review of Noncancer Presentations with a Median Survival of 6 Months or Less
Salpeter, S. R., Luo, E. J., Malter, D. S., & Stuart, B. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2011.07.028 · Cited by 68 · see citing works
Aortic Valve Replacement Should Be Operated on Before Symptom Onset
Carabello, B. A. (2012) · Circulation · doi:10.1161/circulationaha.111.079350 · Cited by 67 · see citing works
Severe Aortic Stenosis Should Not Be Operated on Before Symptom Onset
Shah, P. K. (2012) · Circulation · doi:10.1161/circulationaha.111.079368 · Cited by 54 · see citing works
Goals for the care of frail older adults: do caregivers and clinicians agree?
Bogardus, S. T., Bradley, E. H., Williams, C. S., Maciejewski, P. K., van Doorn, C., & Inouye, S. K. (2001) · The American Journal of Medicine · doi:10.1016/s0002-9343(00)00668-9 · Cited by 50 · see citing works
Kapadia, S. R., Goel, S. S., Yüksel, U. Ç., Agarwal, S., Pettersson, G., Svensson, L. G., Smedira, N. G., Whitlow, P. L., Lytle, B. W., & Tuzcu, E. M. (2010) · Journal of Interventional Cardiology · doi:10.1111/j.1540-8183.2010.00577.x · Cited by 49 · see citing works
McDermid, R. C., & Bagshaw, S. M. (2009) · Philosophy Ethics and Humanities in Medicine · doi:10.1186/1747-5341-4-3 · Cited by 31 · see citing works
Midwall Fibrosis Is an Independent Predictor of Mortality in Patients With Aortic Stenosis
Dweck, M. R., Joshi, S., Murigu, T., Alpendurada, F., Jabbour, A., Melina, G., Banya, W., Gulati, A., Roussin, I., Raza, S., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.03.064 · Cited by 23 · see citing works
Tan, T. C., Flynn, A. W., Rincon, L. M., Nunes, M. P., Mehrotra, P., Agnihotri, A. K., Shahian, D. M., Picard, M. H., & Afilalo, J. (2012) · Circulation · doi:10.1161/circ.126.suppl_21.a19057 · Cited by 1 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Frailty: implications for clinical practice and public health
Hoogendijk, E. O., Afilalo, J., Ensrud, K. E., Kowal, P. R., Onder, G., & Fried, L. P. (2019) · The Lancet · doi:10.1016/s0140-6736(19)31786-6 · Cited by 3,369 · see citing works
Self-citationLindman, B. R., Clavel, M.-A., Mathieu, P., Iung, B., Lancellotti, P., Otto, C. M., & Pibarot, P. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.6 · Cited by 982 · see citing works
Self-citationFrailty in Older Adults Undergoing Aortic Valve Replacement
Afilalo, J., Lauck, S., Kim, D. H., Lefèvre, T., Piazza, N., Lachapelle, K. J., Martucci, G. J., Lamy, A. L., Labinaz, M. X., Peterson, M. D., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.06.024 · Cited by 838 · see citing works
Self-citationOtto, C. M., Kumbhani, D. J., Alexander, K. P., Calhoon, J., Desai, M. Y., Kaul, S., Lee, J. C., Ruiz, C. E., & Vassileva, C. M. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.12.006 · Cited by 512 · see citing works
Self-citationDamluji, A. A., Forman, D. E., Wang, T. Y., Chikwe, J., Kunadian, V., Rich, M. W., Young, B. A., Page, R. L., II, DeVon, H. A., & Alexander, K. P. (2022) · Circulation · doi:10.1161/cir.0000000000001112 · Cited by 381 · see citing works
Self-citationEdwards, F. H., Cohen, D. J., O’Brien, S. M., Peterson, E. D., Mack, M. J., Shahian, D. M., Grover, F. L., Tuzcu, E. M., Thourani, V. H., Carroll, J. D., et al. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2015.0326 · Cited by 285 · see citing works
Green, P., Arnold, S. V., Cohen, D. J., Kirtane, A. J., Kodali, S., Brown, D. L., Rihal, C. S., Xu, K., Lei, Y., Hawkey, M., et al. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.03.061 · Cited by 247 · see citing works
Cardiac Imaging for Assessing Low-Gradient Severe Aortic Stenosis
Clavel, M.-A. A., Burwash, I. G., & Pîbarot, P. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.01.002 · Cited by 207 · see citing works
Jha, S. R., Hannu, M. K., Chang, S., MONTGOMERY, E. E., Harkess, M., Wilhelm, K. A., Hayward, C., Jabbour, A., Spratt, P. M., Newton, P. J., et al. (2015) · Transplantation · doi:10.1097/tp.0000000000000991 · Cited by 186 · see citing works
Gait Speed and Operative Mortality in Older Adults Following Cardiac Surgery.
Afilalo, J., Kim, S., O’Brien, S., Brennan, J. M., Edwards, F. H., Mack, M. J., McClurken, J. B., Cleveland, J. C., Smith, P. K., Shahian, D. M., et al. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2016.0316 · Cited by 175 · see citing works
Self-citationBavaria, J. E., Tommaso, C. L., Brindis, R. G., Carroll, J. D., Deeb, G. M., Feldman, T. E., Gleason, T. G., Horlick, E. M., Kavinsky, C. J., Kumbhani, D. J., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.07.002 · Cited by 160 · see citing works
Therapeutic Interventions for Frail Elderly Patients: Part I. Published Randomized Trials
Bibas, L., Levi, M., Bendayan, M., Mullie, L., Forman, D. E., & Afilalo, J. (2014) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2014.07.004 · Cited by 150 · see citing works
Self-citationLip, G. Y. H., Collet, J., Caterina, R. D., Fauchier, L., Lane, D. A., Larsen, T. B., Marín, F. R., Morais, J., Narasimhan, C., Olshansky, B., et al. (2017) · EP Europace · doi:10.1093/europace/eux240 · Cited by 139 · see citing works
Lindman, B. R., Breyley, J. G., Schilling, J. D., Vatterott, A. M., Zajarias, A., Maniar, H. S., Damiano, R. J., Moon, M. R., Lawton, J. S., Gage, B. F., et al. (2015) · Heart · doi:10.1136/heartjnl-2015-307742 · Cited by 114 · see citing works
Self-citation2019 Canadian Cardiovascular Society Position Statement for Transcatheter Aortic Valve Implantation
Asgar, A., Ouzounian, M., Adams, C. A., Afilalo, J., Fremes, S. E., Lauck, S., Leipsic, J. A., Piazza, N., Rodés‐Cabau, J., Welsh, R. C., et al. (2019) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2019.08.011 · Cited by 110 · see citing works
Self-citationManagement strategies and future challenges for aortic valve disease
Bonow, R. O., Leon, M. B., Doshi, D., & Moat, N. E. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00586-9 · Cited by 107 · see citing works
López-Moya, M., Melgar‐Lesmes, P., Kolandaivelu, K., Hernández, J. M. D. L. T., Edelman, E. R., & Balcells, M. (2018) · Biomacromolecules · doi:10.1021/acs.biomac.8b00077 · Cited by 100 · see citing works
Aortic valve disease in the older adult.
Bhatia, N. K., Basra, S. S., Skolnick, A. H., & WENGER, N. K. (2016) · Europe PMC (PubMed Central) · doi:10.11909/j.issn.1671-5411.2016.12.004 · Cited by 83 · see citing works
Kiani, S., Stebbins, A. S., Thourani, V. H., Forcillo, J., Vemulapalli, S., Kosinski, A. S., Babaliaros, V. C., Cohen, D. J., Kodali, S., Kirtane, A. J., et al. (2020) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.08.015 · Cited by 73 · see citing works
Quality of Life After Transcatheter Aortic Valve Replacement
Lange, R., Beckmann, A., Neumann, T., Krane, M., Deutsch, M.-A., Landwehr, S., Kötting, J., Welz, A., Zahn, R., Cremer, J., et al. (2016) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2016.09.050 · Cited by 68 · see citing works
Geriatric Cardiology: Coming of Age
Goyal, P., Kwak, M. J., Malouf, C. A., Kumar, M., Rohant, N., Damluji, A. A., Denfeld, Q. E., Bircher, K. K., Krishnaswami, A., Alexander, K. P., et al. (2022) · JACC Advances · doi:10.1016/j.jacadv.2022.100070 · Cited by 63 · see citing works
Self-citationAfilalo, J. (2017) · Circulation · doi:10.1161/circulationaha.116.025958 · Cited by 63 · see citing works
Self-citationTranscatheter aortic valve replacement: current perspectives and future implications
Agarwal, S., Tuzcu, E. M., Krishnaswamy, A., Schoenhagen, P., Stewart, W. J., Svensson, L. G., & Kapadia, S. R. (2014) · Heart · doi:10.1136/heartjnl-2014-306254 · Cited by 59 · see citing works
Lip, G. Y. H., Collet, J., Caterina, R. D., Fauchier, L., Lane, D. A., Larsen, T. B., Marín, F. R., Morais, J., Narasimhan, C., Olshansky, B., et al. (2017) · Thrombosis and Haemostasis · doi:10.1160/th-17-10-0709 · Cited by 55 · see citing works
Sinning, J., Wollert, K. C., Sedaghat, A., Widera, C., Radermacher, M.-C., Descoups, C., Hammerstingl, C., Weber, M., Stundl, A., Ghanem, A., et al. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.07.003 · Cited by 54 · see citing works
Frailty Status and Outcomes After Transcatheter Aortic Valve Implantation
Huded, C. P., Huded, J. M., Friedman, J. L., Benck, L. R., Lindquist, L. A., Holly, T. A., Sweis, R. N., Ricciardi, M. J., Malaisrie, S. C., Davidson, C. J., et al. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.03.044 · Cited by 54 · see citing works
Developing a Clinically Relevant Tissue Engineered Heart Valve—A Review of Current Approaches
Nachlas, A. L. Y., Li, S., & Davis, M. E. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700918 · Cited by 54 · see citing works
Contemporary Management of Severe Symptomatic Aortic Stenosis
Eugène, M., Duchnowski, P., Prendergast, B., Wendler, O., Laroche, C., Monin, J., Jobic, Y., Popescu, B. A., Bax, J. J., Vahanian, A. S., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.09.864 · Cited by 53 · see citing works
Lindman, B. R., Arnold, S. V., Bagur, R., Clarke, L., Coylewright, M. J., Evans, F., Hung, J., Lauck, S., Peschin, S., Sachdev, V., et al. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015975 · Cited by 51 · see citing works
Self-citationOutcomes in Nonagenarians Undergoing Transcatheter Aortic Valve Replacement in the PARTNER-I Trial
Thourani, V. H., Jensen, H., Babaliaros, V. C., Kodali, S., Rajeswaran, J., Ehrlinger, J., Blackstone, E. H., Suri, R. M., Don, C. W., Aldea, G. S., et al. (2015) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2015.05.021 · Cited by 49 · see citing works
Vallabhajosyula, S., Patlolla, S. H., Sandhyavenu, H., Vallabhajosyula, S., Barsness, G. W., Dunlay, S. M., Greason, K. L., Holmes, D. R., & Eleid, M. F. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.009608 · Cited by 45 · see citing works
Comorbidity and intervention in octogenarians with severe symptomatic aortic stenosis
Martínez‐Sellés, M., Díez‐Villanueva, P., Sánchez-Sendín, D., Carro, A., Gómez‐Doblas, J. J., de la Villa, B. G., Cornide, L., Alonso, A., Ogando, R. A., Ripoll‐Vera, T., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.04.017 · Cited by 44 · see citing works
JCS/JHFS 2021 Statement on Palliative Care in Cardiovascular Diseases
Anzai, T., Sato, T., Fukumoto, Y., Izumi, C., Kizawa, Y., Koga, M., Nishimura, K., Ohishi, M., Sakashita, A., Sakata, Y., et al. (2021) · Circulation Journal · doi:10.1253/circj.cj-20-1127 · Cited by 44 · see citing works
Eleid, M. F., Michelena, H. I., Nkomo, V. T., Nishimura, R. A., Malouf, J. F., Scott, C. G., & Pellikka, P. A. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jev091 · Cited by 43 · see citing works
Chauhan, D., Haik, N., Merlo, A. E., Haik, B. J., Chen, C., Cohen, M. C., Mosenthal, A. C., & Russo, M. J. (2016) · American Heart Journal · doi:10.1016/j.ahj.2016.06.028 · Cited by 42 · see citing works
Saji, M., Higuchi, R., Tobaru, T., Iguchi, N., Takanashi, S., Takayama, M., & Isobe, M. (2017) · Circulation Journal · doi:10.1253/circj.cj-17-0816 · Cited by 42 · see citing works
Damluji, A. A., Bernacki, G., Afilalo, J., Lyubarova, R., Orkaby, A. R., Kwak, M. J., Hummel, S., Kirkpatrick, J. N., Maurer, M. S., Wenger, N., et al. (2024) · JACC: Advances · doi:10.1016/j.jacadv.2024.100877 · Cited by 41 · see citing works
Self-citationPascual, C., Paredes-Galán, E., Ferrero-Martínez, A. I., Baz-Alonso, J. A., Durán‐Muñoz, D., González‐Babarro, E., Sanmartı́n, M., Parajes, T., Torres-Torres, I., Piñón, M., et al. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.09.020 · Cited by 37 · see citing works
GAIT SPEED AND OPERATIVE MORTALITY IN OLDER ADULTS FOLLOWING CARDIAC SURGERY
Afilalo, J., Kim, S., O'Brien, S., Brennan, J. M., Edwards, F. H., Mack, M. J., McClurken, J. B., Cleveland, J. C., Smith, P. K., Shahian, D. M., et al. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.07.394 · Cited by 36 · see citing works
Self-citationTang, L., Gössl, M., Ahmed, A. K., Garberich, R., Bradley, S. M., Niikura, H., Witt, D., Pedersen, W. R., Bae, R. Y., Lesser, J. R., et al. (2018) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.118.007220 · Cited by 36 · see citing works
Pulignano, G., Gulizia, M. M., Baldasseroni, S., Bedogni, F., Cioffi, G., Indolfi, C., Romeo, F., Murrone, A., Musumeci, F., Parolari, A., et al. (2017) · European Heart Journal Supplements · doi:10.1093/eurheartj/sux012 · Cited by 35 · see citing works
Mesnier, J., Cruz‐González, I., Arzamendi, D., Freixa, X., y, L. N.-F., Peral, V., Caneiro‐Queija, B., Mangieri, A., Trejo‐Velasco, B., Asmarats, L., et al. (2022) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2022.06.012 · Cited by 34 · see citing works
Transcatheter Aortic Valve Implantation in Patients With Advanced Chronic Kidney Disease
Conrotto, F., Salizzoni, S., Andreis, A., D’Ascenzo, F., D’Onofrio, A., Agrifoglio, M., Chieffo, A., Colombo, A., Rapetto, F., Santini, F., et al. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.01.042 · Cited by 33 · see citing works
González-Ferreiro, R., Muñoz-García, A. J., López‐Otero, D., y, P. A., Pascual, I., Alonso-Briales, J. H., González‐Juanatey, J. R., Pun, F., Jiménez-Navarro, M. F., Hernández-García, J. M., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.11.097 · Cited by 33 · see citing works
O’Leary, J., Clavel, M.-A. A., Chen, S., Goel, K., O'Neill, B. P., Elmariah, S., Crowley, A., Alu, M. C., Thourani, V. H., Leon, M. B., et al. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.2614 · Cited by 32 · see citing works
Self-citationLindman, B. R., Gillam, L. D., Coylewright, M. J., Welt, F. G. P., Elmariah, S., Smith, S. A., McKeel, D. A., Jackson, N. A., Mukerjee, K., Cloud, H., et al. (2021) · European Heart Journal - Digital Health · doi:10.1093/ehjdh/ztab007 · Cited by 32 · see citing works
Self-citationNatural history observations in moderate aortic stenosis
Du, Y., Gössl, M., García, S., Enriquez-Sarano, M. L., Cavalcante, J. L., Bae, R. Y., Hashimoto, G., Fukui, M., Lopes, B. B. C., Ahmed, A. K., et al. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-01901-1 · Cited by 32 · see citing works
Harbaoui, B., Montoy, M., Charles, P., Boussel, L., Liebgott, H., Girerd, N., Courand, P., & Lantelme, P. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.01.013 · Cited by 31 · see citing works
Derivation and Validation of Prognosis-Based Age Cutoffs to Define Elderly in Cardiac Surgery
Afilalo, J., Steele, R. J., Manning, W. J., Khabbaz, K. R., Rudski, L., Langlois, Y., Morin, J., & Picard, M. H. (2016) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.115.002409 · Cited by 31 · see citing works
Self-citationPrognostic value of body mass index in transcatheter aortic valve implantation: A “J”-shaped curve
González-Ferreiro, R., Muñoz-García, A. J., López‐Otero, D., y, P. A., Pascual, I., Alonso-Briales, J. H., Trillo, R., Pun, F., Jiménez-Navarro, M. F., Hernández-García, J. M., et al. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.12.051 · Cited by 29 · see citing works
Straiton, N., Jin, K., Bhindi, R., & Gallagher, R. D. (2017) · Age and Ageing · doi:10.1093/ageing/afx203 · Cited by 29 · see citing works
Zheng, C., Huang, X., Ding, K., Kuang, D., Li, Y., Wang, Y., & Zhang, X. (2022) · Composites Part B Engineering · doi:10.1016/j.compositesb.2022.110448 · Cited by 28 · see citing works
Multimorbidity in Older Adults with Aortic Stenosis
Lindman, B. R., & Patel, J. N. (2016) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2016.01.006 · Cited by 28 · see citing works
Self-citationvan Beek-Peeters, J. J. A. M., van Noort, E. H. M., Faes, M. C., de Vos, A., van Geldorp, M. W. A., Minkman, M. M. N., & van der Meer, N. J. M. (2020) · Heart · doi:10.1136/heartjnl-2019-316055 · Cited by 27 · see citing works
Gill, H., Chehab, O., Allen, C. J., Patterson, T., Redwood, S. R., Rajani, R., & Prendergast, B. (2021) · European Journal of Heart Failure · doi:10.1002/ejhf.2097 · Cited by 27 · see citing works
Goel, K., O’Leary, J., Barker, C. M., Levack, M. M., Rajagopal, V., Makkar, R., BAJWA, T. K., Kleiman, N. S., Linke, A. H.-P., Kereiakes, D. J., et al. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.017075 · Cited by 25 · see citing works
Self-citationMaeda, K., Kumamaru, H., Kohsaka, S., Shimamura, K., Mizote, I., Yamashita, K., Kawamura, A., Mukai, T., Nakamura, D., Takeda, Y., et al. (2022) · JACC Asia · doi:10.1016/j.jacasi.2022.06.002 · Cited by 25 · see citing works
Zusman, O., Kornowski, R., Witberg, G., Lador, A., Orvin, K., Levi, A., Assali, A., Assa, H. V., Sharony, R., Shapira, Y., et al. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.09.007 · Cited by 25 · see citing works
Saji, M., Tobaru, T., Higuchi, R., Hagiya, K., Takamisawa, I., Shimizu, J., Iguchi, N., Takanashi, S., Takayama, M., & Isobe, M. (2019) · Journal of Cardiology · doi:10.1016/j.jjcc.2019.03.017 · Cited by 25 · see citing works
Prevalence and Prognostic Implications of Frailty in Transcatheter Aortic Valve Replacement
Piankova, P., & Afilalo, J. (2019) · Cardiology Clinics · doi:10.1016/j.ccl.2019.09.011 · Cited by 25 · see citing works
Self-citationGeriatría transversal. Un reto asistencial para el siglo xxi
González-Montalvo, J. I., Ramírez-Martín, R., Colino, R. M., Alarcón, T., Tarazona‐Santabalbina, F. J., Martínez‐Velilla, N., Vidán, M. T., Pi‐Figueras, M., Formiga, F., Rodríguez‐Couso, M., et al. (2019) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2019.10.011 · Cited by 25 · see citing works
González-Ferreiro, R., López‐Otero, D., Rodríguez, L. Á., García, Ó. O., Pérez-Poza, M., Muiños, P. J. A., Antonio, C. E. C., López‐País, J., Juskova, M., Álvarez, A. B. C., et al. (2021) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.120.009342 · Cited by 24 · see citing works
Transition to palliative care when transcatheter aortic valve implantation is not an option
Lauck, S., Gibson, J. A., Baumbusch, J., Carroll, S. L., Achtem, L., Kimel, G., Nordquist, C., Cheung, A. W., Boone, R. H., Ye, J., et al. (2015) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000180 · Cited by 24 · see citing works
Impact of Cancer in Patients Undergoing Transcatheter Aortic Valve Replacement
Lind, A. Y., Totzeck, M., Mahabadi, A. A., Jánosi, R. A., Gabry, M. E., Ruhparwar, A., Mrotzek, S. M., Hinrichs, L., Akdeniz, M., Rassaf, T., et al. (2020) · JACC CardioOncology · doi:10.1016/j.jaccao.2020.11.008 · Cited by 24 · see citing works
Saia, F., Moretti, C., Dall’Ara, G., Ciuca, C., Taglieri, N., Berardini, A., Gallo, P., Cannizzo, M., Chiarabelli, M., Ramponi, N., et al. (2016) · PubMed Central · doi:10.11909/j.issn.1671-5411.2016.06.002 · Cited by 23 · see citing works
Gallone, G., Depaoli, A., D’Ascenzo, F., Tore, D., Allois, L., Bruno, F., Casale, M., Atzeni, F., LIO, G. D., Bocchino, P. P., et al. (2021) · Journal of cardiovascular computed tomography · doi:10.1016/j.jcct.2021.12.001 · Cited by 23 · see citing works
Jafari, M. T., Kour, K., Giebel, S., Omisore, I., & Prasad, B. (2020) · Canadian Journal of Kidney Health and Disease · doi:10.1177/2054358120917780 · Cited by 22 · see citing works
Baseline NT‐proBNP Accurately Predicts Symptom Response to Transcatheter Aortic Valve Implantation
Allen, C. J., Joseph, J. P., Patterson, T., Hammond‐Haley, M., McConkey, H. Z. R., Prendergast, B., Marber, M. S., & Redwood, S. R. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.017574 · Cited by 22 · see citing works
Li, Y., Xiong, T., Xu, K., Fang, Z., Jiang, L., Jin, J., He, S., Yang, Y., He, J., Jia, Y., et al. (2021) · PubMed Central · doi:10.1097/cm9.0000000000001882 · Cited by 10 · see citing works
Transcatheter aortic valve replacement over age 90: Risks vs benefits
Galatas, C., & Afilalo, J. (2019) · Clinical Cardiology · doi:10.1002/clc.23310 · Cited by 20 · see citing works
Self-citationHecht, S., Giuliani, C., Nuche, J., Farjat-Pasos, J. I., Bernard, J., Tastet, L. L., Abu-Alhayja’a, R., Beaudoin, J., Côté, N., DeLarochellière, R., et al. (2023) · JACC Advances · doi:10.1016/j.jacadv.2023.100761 · Cited by 20 · see citing works
Palliative Care for Patients With Advanced Heart Disease
Klinedinst, R., Kornfield, Z. N., & Hadler, R. A. (2018) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2018.04.047 · Cited by 20 · see citing works
Onorati, F., D’Onofrio, A., Biancari, F., Salizzoni, S., FEO, M. D., Agrifoglio, M., Mariscalco, G., Lucchetti, V., Messina, A., Musumeci, F., et al. (2016) · Interactive Cardiovascular and Thoracic Surgery · doi:10.1093/icvts/ivw049 · Cited by 18 · see citing works
Piccirillo, G., Moscucci, F., Mastropietri, F., Iorio, C. D., Mariani, M. V., Fabietti, M., Stricchiola, G. M. G., Parrotta, I., Sardella, G., Mancone, M., et al. (2018) · Clinical Interventions in Aging · doi:10.2147/cia.s170226 · Cited by 18 · see citing works
Transcatheter Aortic Valve Replacement in the Care of Older Persons with Aortic Stenosis
Talbot‐Hamon, C., & Afilalo, J. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14776 · Cited by 18 · see citing works
Self-citationTranscatheter Aortic Valve Implantation: The New Challenges of Cardiac Rehabilitation
Sperlongano, S., Renon, F., Bigazzi, M. C., Sperlongano, R., Cimmino, G., D’Andrea, A., & Golino, P. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10040810 · Cited by 18 · see citing works
Csordás, A., Nietlispach, F., Schüetz, P., Huber, A., Müller, B., Maisano, F., Taramasso, M., Moarof, I., Obeid, S. N., Stähli, B. E., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143761 · Cited by 17 · see citing works
Haemodynamic outcomes following aortic valve-in-valve procedure
Zenses, A., Dahou, A., Salaün, E., Clavel, M.-A. A., Rodés‐Cabau, J., Ong, G., Guzzetti, E., Côté, M., Larochellière, R. D., Paradis, J., et al. (2018) · Open Heart · doi:10.1136/openhrt-2018-000854 · Cited by 17 · see citing works
Tomii, D., Lanz, J., Heg, D., Möllmann, H., Kim, W.-K., Burgdorf, C., Linke, A. H.-P., Redwood, S. R., Hilker, M., Joner, M., et al. (2025) · JACC Advances · doi:10.1016/j.jacadv.2025.101594 · Cited by 16 · see citing works
Brunetti, E., Lucà, F., Presta, R., Marchionni, N., Boccanelli, A., Ungar, A., Rao, C. M., Ingianni, N., Lettino, M., Sindaco, D. D., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13144169 · Cited by 16 · see citing works
Saji, M., Highchi, R., Iguchi, N., Shimuzu, J., Tobaru, T., Takanashi, S., Takayama, M., & Isobe, M. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.11.090 · Cited by 16 · see citing works
Jain, H., Goyal, A., Khan, A. T. M. A., Khan, N. U., Jain, J., Chopra, S., Sulaiman, S. A., Reddy, M. M., Patel, K., Khullar, K., et al. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000002106 · Cited by 15 · see citing works
Bavaria, J. E., Tommaso, C. L., Brindis, R. G., Carroll, J. D., Deeb, G. M., Feldman, T. E., Gleason, T. G., Horlick, E. M., Kavinsky, C. J., Kumbhani, D. J., et al. (2018) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.27811 · Cited by 15 · see citing works
de Ronde, M., Goudzwaard, J. A., Faquir, N. E., Mieghem, N. M. V., Mattace-Raso, F. U. S., Cummins, P. A., Lenzen, M. J., & de Jaegere, P. P. T. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.12.005 · Cited by 15 · see citing works
Wang, Y., Li, C., Ma, Y., Zheng, F., & Xie, W. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.939310 · Cited by 14 · see citing works
Professionals’ views on shared decision-making in severe aortic stenosis
van Beek-Peeters, J. J. A. M., van der Meer, J. B. L., Faes, M. C., de Vos, A., van Geldorp, M. W. A., den Branden, B. J. L. V., Pel‐Littel, R. E., van der Meer, N. J. M., & Minkman, M. M. N. (2021) · Heart · doi:10.1136/heartjnl-2021-320194 · Cited by 14 · see citing works
Bavaria, J. E., Tommaso, C. L., Brindis, R. G., Carroll, J. D., Deeb, G. M., Feldman, T. E., Gleason, T. G., Horlick, E. M., Kavinsky, C. J., Kumbhani, D. J., et al. (2018) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2018.07.001 · Cited by 13 · see citing works
Lauck, S., Achtem, L., Borregaard, B., Baumbusch, J., Afilalo, J., Wood, D. A., Forman, J. M., Cheung, A. W., Ye, J., & Webb, J. G. (2020) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515120953739 · Cited by 13 · see citing works
Self-citationShimura, T., Yamamoto, M., Yamaguchi, R., Adachi, Y., Sago, M., Tsunaki, T., Kagase, A., Koyama, Y., Otsuka, T., Yashima, F., et al. (2021) · ESC Heart Failure · doi:10.1002/ehf2.13270 · Cited by 13 · see citing works
Tang, G. H. L., Lansman, S. L., & Panza, J. A. (2014) · Cardiology in Review · doi:10.1097/crd.0000000000000043 · Cited by 12 · see citing works
Mukdad, L. A., Kashani, R. G., Mantha, A., Sareh, S., Mendelsohn, A. H., & Benharash, P. (2018) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2018.05.040 · Cited by 12 · see citing works
Romeo, F. J., Seropian, I. M., Chiabrando, J. G., Raleigh, J. V., Smietniansky, M., Cal, M., Falconi, M. L., Kotowicz, V., Agatiello, C. R., & Berrocal, D. H. (2020) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.29067 · Cited by 12 · see citing works
El-Sabawi, B. R., Cloud, H., Patel, J. N., Bell, S. P., Elmariah, S., Fearon, W. F., Kim, J. B., Piana, R. N., Kapadia, S. R., Kumbhani, D. J., et al. (2023) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.123.012875 · Cited by 12 · see citing works
Self-citationAssessing Risks and Benefits of Invasive Cardiac Procedures in Patients with Advanced Multimorbidity
Orkaby, A. R., & Forman, D. E. (2016) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2016.01.004 · Cited by 12 · see citing works
Deng, C., Mitchell, S. J., Paine, S., & Kerse, N. M. (2019) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2019-212283 · Cited by 12 · see citing works
Deng, M. C.-H. K. (2018) · Biomarkers in Medicine · doi:10.2217/bmm-2018-0097 · Cited by 12 · see citing works
Relation of Frailty to Cost for Patients Undergoing Transcatheter Aortic Valve Implantation
Patel, J. N., Ahmad, M., Kim, M. C., Banga, S., Asche, C. V., Barzallo, M. A., & Mungee, S. (2019) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2019.10.021 · Cited by 11 · see citing works
Saji, M., Higuchi, R., Saitoh, M., Hagiya, K., Izumi, Y., Takamisawa, I., Iguchi, N., Nanasato, M., Shimizu, J., Tobaru, T., et al. (2020) · Journal of Cardiology · doi:10.1016/j.jjcc.2020.07.021 · Cited by 11 · see citing works
Intervention for Aortic Stenosis
Mack, M. J., & Stoler, R. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.06.035 · Cited by 11 · see citing works
Tirado‐Conte, G., Espejo‐Paeres, C., y, L. N.-F., Jiménez‐Quevedo, P., Cobiella, J., Vivas, D., de Agustín, J. A., McInerney, A., Pozo, E., Salinas, P., et al. (2020) · Journal of Cardiac Surgery · doi:10.1111/jocs.15116 · Cited by 10 · see citing works
- Authors
- Lindman, B. R., Alexander, K. P., O'Gara, P. T., & Afilalo, J.
- Affiliations
- Washington University in St. Louis (US)
- Duke University (US)
- Jewish General Hospital (CA)
- Corresponding author
- Lindman, Brian R.
- Venue
- JACC: Cardiovascular Interventions
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 7
- Issue
- 7
- Pages
- 707-716
- ISSN
- 1876-7605 (ISSN-L)
- 1936-8798
- PMC
- PMC4322002
- OpenAlex
- W1973241413
- Cited by
- 222
- References
- 70
- Citations by year
- 2026: 7 · 2025: 19 · 2024: 8 · 2023: 10 · 2022: 18 · 2021: 20 · 2020: 23 · 2019: 17 · 2018: 23 · 2017: 22 · 2016: 25 · 2015: 23 · 2014: 6
- FWCI
- 4.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- JACC: Cardiovascular Interventions (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Washington University Institute of Clinical and Translational Sciences (#UL1 TR000448, #KL2 TR000450)
- BG Medicine
- Roche Diagnostics
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Disease and Treatment Approaches
- Keywords
- transcatheter aortic valve implantation, aortic stenosis, futility of treatment, anticipated benefits, very elderly patients, multimorbidity, frailty, cognitive impairment, disability, risk stratification, end-of-life care, shared decision-making, quality of life
- MeSH terms
- Age Factors, Aged, Aged, 80 and over, Aortic Valve, Aortic Valve Stenosis, Decision Support Techniques, Cardiac Catheterization, Heart Valve Prosthesis, Hemodynamics, Humans, Middle Aged, Prosthesis Design, Risk Factors, Severity of Illness Index, Geriatric Assessment, Comorbidity, Frail Elderly, Treatment Outcome, Medical Futility, Risk Assessment, Patient Selection, Heart Valve Prosthesis Implantation, Patient Preference
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
