Clinical Profile and Influences on Outcomes in Patients Hospitalized for Acute Pericarditis
Abstract
Background The clinical profile with regard to sex and the influences on outcomes in patients who have been hospitalized for acute pericarditis is largely uncharacterized. Methods and results We studied all patients aged ≥16 years admitted to the hospital because of acute pericarditis (postpericardiotomy and myocardial infarction associated pericarditis were excluded). Data were collected from a Finnish national registry that included data on all cardiovascular admissions (670 409) during 9.5 years in 29 hospitals nationwide. During the study period, there were 1361 admissions for acute pericarditis. Pericarditis patients were more likely to be male (64.9% of patients) than female (35.1%), with an age-adjusted likelihood ratio of 1.85 (95% confidence interval [CI], 1.65-2.06; P Conclusions Patients hospitalized for acute pericarditis are more commonly male. Increasing age and severe coinfection are associated with greater in-hospital mortality in hospitalized acute pericarditis patients.
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Pre-COVID pericarditis occurs more often in young men under 50 years with a sex ratio of around 2:1.
“Similar to myocarditis, preCOVID pericarditis occurs more often in young men under the age of 50 years with a sex ratio of around 2:1. 64,95,118”
From COVID-19, Myocarditis and Pericarditis (2023) · cites this paper as [95]
The incidence of acute pericarditis pre-COVID in a large Finnish registry of all cardiovascular patients (n=670,409) was 3.3 cases per 100,000 individuals.
“The incidence of acute pericarditis pre-COVID in a large Finnish registry of all cardiovascular patients (n=670 409) was 3.3 cases/100 000 individuals.”
From COVID-19, Myocarditis and Pericarditis (2023) · cites this paper as [95]
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Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination
Marshall, M., Ferguson, I. D., Lewis, P., Jaggi, P., Gagliardo, C., Collins, J. S., Shaughnessy, R., Caron, R., Fuss, C., Corbin, K. J. E., et al. (2021) · Pediatrics · doi:10.1542/peds.2021-052478 · Cited by 367 · see citing works
COVID-19, Myocarditis and Pericarditis
Fairweather, D., Beetler, D. J., Di Florio, D. N., Musigk, N., Heidecker, B., & Cooper, L. T. (2023) · Circulation Research · doi:10.1161/circresaha.123.321878 · Cited by 181 · see citing works
- Authors
- Kytö, V., Sipilä, J., & Rautava, P.
- Affiliations
- University of Turku (FI)
- Venue
- Circulation
- Published
- 2014-10-28
- Volume
- 130
- Issue
- 18
- Pages
- 1601-1606
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2054361459
- Cited by
- 219
- References
- 0
- Citations by year
- 2026: 18 · 2025: 14 · 2024: 16 · 2023: 30 · 2022: 28 · 2021: 24 · 2020: 20 · 2019: 19 · 2018: 7 · 2017: 13 · 2016: 14 · 2015: 15 · 2014: 1
- FWCI
- 9.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Pericarditis and Cardiac Tamponade
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Streptococcal Infections and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Keywords
- acute pericarditis, sex differences, in-hospital mortality, age-related risk, co-infection, pneumonia, septicemia, cardiovascular hospitalization, incidence trends, clinical profile, risk factors, young adults, cardiovascular admissions, mortality risk stratification
- MeSH terms
- Acute Disease, Adolescent, Adult, Aged, Female, Finland, Hospitalization, Hospitals, University, Humans, Male, Middle Aged, Pericarditis, Prognosis, Risk Factors, Comorbidity, Incidence, Hospital Mortality, Outcome Assessment, Health Care, Age Distribution, Sex Distribution, Young Adult
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