The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone
Open accessAbstract
Background—: Impairment in left ventricular systolic function has been described in heart failure (HF) with preserved ejection fraction (HFpEF), but its prognostic relevance is not known. We determined whether left ventricular longitudinal strain (LS) is predictive of cardiovascular outcomes in HFpEF beyond clinical and conventional echocardiographic measures. Methods and Results—: LS was assessed by 2-dimensional speckle-tracking echocardiography at baseline in 447 patients with HFpEF enrolled in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) trial. At a median follow-up of 2.6 years (interquartile range, 1.5–3.9 years), 115 patients experienced the primary composite outcome of cardiovascular death, HF hospitalization, or aborted cardiac arrest. Impaired LS, defined as an absolute LS <15.8%, was present in 52% of patients and was predictive of the composite outcome (adjusted hazard ratio, 2.14; 95% confidence interval, 1.26–3.66; P =0.005), cardiovascular death alone (adjusted hazard ratio, 3.20; 95% confidence interval, 1.44–7.12; P =0.004), and HF hospitalization alone (adjusted hazard ratio, 2.23; 95% confidence interval, 1.16–4.28; P =0.016) after adjustment for clinical and conventional echocardiographic variables. LS was the strongest echocardiographic predictor of the composite outcome. Exploratory analysis in a subset of 131 patients with follow-up LS assessed after 12 to 18 months demonstrated a trend toward improvement in LS associated with spironolactone in patients enrolled in the Americas but not in Russia or Georgia. Conclusions—: Impaired left ventricular systolic function is a powerful predictor of HF hospitalization, cardiovascular death, or aborted cardiac arrest in HFpEF independent of clinical predictors. Impaired LS represents a novel imaging biomarker to identify patients with HFpEF at particularly high risk for cardiovascular morbidity and mortality. Clinical Trial Registration—: URL: http://www.clinicaltrials.gov . Unique identifier: NCT00094302.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ahmed, A., Jorna, T., & Bhandari, S. (2016) · The Nephron journals/Nephron journals · doi:10.1159/000447068 · Cited by 11,782
Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318
Self-citationRudski, L., Lai, W. W., Afilalo, J., Hua, L., Handschumacher, M. D., Chandrasekaran, K., Solomon, S. D., Louie, E. K., & Schiller, N. B. (2010) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2010.05.010 · Cited by 7,080
Self-citationTrends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction
Owan, T., Hodge, D. O., Herges, R. M., Jacobsen, S. J., Roger, V. L., & Redfield, M. M. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052256 · Cited by 4,209
THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUDY: DESIGN AND OBJECTIVES
THE ARIC INVESTIGATORS (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115184 · Cited by 3,510
(1989) · PubMed · Cited by 3,139
Yusuf, S., Pfeffer, M. A., Swedberg, K., Granger, C. B., Held, P., McMurray, J. J., Michelson, E. L., Olofsson, B., & Östergren, J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14285-7 · Cited by 2,994
Self-citationSpironolactone for heart failure with preserved ejection fraction
Pitt, B., Pfeffer, M. A., Assmann, S. F., Boineau, R., Anand, I. S., Claggett, B., Clausell, N., Desai, A. S., Diaz, R., Fleg, J. L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1313731 · Cited by 2,809
Self-citationAntlanger, M., Aschauer, S., Kopecky, C., Hecking, M., Kovarik, J. J., Werzowa, J. M., Mascherbauer, J., Genser, B., Säemann, M. D., & Bonderman, D. (2017) · Kidney & Blood Pressure Research · doi:10.1159/000473868 · Cited by 2,808
Paulus, W. J., Tschöpe, C., Sanderson, J. E., Rusconi, C., Flachskampf, F. A., Rademakers, F. E., Marino, P. N., Smiseth, O. A., Keulenaer, G. W. D., Leite-Moreira, A. F., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm037 · Cited by 2,646
Flagged first, then by citations
Cited by
Sorted by citations
Items 301–400 of 478
Huang, X.-M., Li, J., Yin, W., Fu, H., Yu, F., Gu, L.-Q., Zhang, Y., Du, M., Ye, Z., & Xu, L. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03744-y · Cited by 6
Making the Case for an Expanded Indication for Sacubitril/Valsartan in Heart Failure
Solomon, S. D., & McMurray, J. J. V. (2021) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2021.04.008 · Cited by 6
Self-citationFerreira, J. P., Shah, A. M., Claggett, B. L., Pitt, B., Lewis, E. F., Solomon, S. D., & Zannad, F. M. (2022) · International Journal of Cardiology · doi:10.1016/j.ijcard.2022.01.053 · Cited by 6
Self-citationCosta, K. D., Wong, A. O. T., Mak, S. Y., Roberts, E. G., Keung, W., Correia, C., Walentinsson, A., Christoffersson, J., Cheung, A., Lieu, D. K., et al. (2024) · bioRxiv · doi:10.1101/2024.08.27.609034 · Cited by 5
The Key Role of Diagnostic Imaging in Early HFpEF
Yaku, H., & Shah, S. J. (2025) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2025.05.016 · Cited by 5
Self-citationLi, Y., Wang, C., Hung, C., Wu, Y., Hsu, C., Tsou, Y., Wang, C., Wu, C., Lin, P., Chang, H., et al. (2024) · PubMed Central · doi:10.6515/acs.202403_40(2).20240206a · Cited by 5
Lewis, G. A., Pearce, K., Williams, S. G., Schelbert, E. B., Macnab, A., & Miller, C. (2020) · Heart Failure Reviews · doi:10.1007/s10741-020-10047-9 · Cited by 7
Burke, G. M., Silva, B. A., Marum, A. A., Bortolotto, A. L., Nearing, B. D., Chen, M. J., Fostello, S. E., Popma, J. J., Verrier, R. L., & Chang, J. D. (2021) · Open Heart · doi:10.1136/openhrt-2020-001542 · Cited by 5
Kinugasa, Y., Sugihara, S., Yamada, K., Miyagi, M., MATSUBARA, K., Kato, M., & Yamamoto, K. (2016) · Journal of Aging Research and Lifestyle · doi:10.14283/jarcp.2016.116 · Cited by 5
Echocardiography in patients with heart failure: recent advances and future perspectives
Kosmala, W., Marwick, T. H., & Przewłocka‐Kosmala, M. (2020) · Kardiologia Polska · doi:10.33963/kp.15720 · Cited by 5
Cotella, J. I., Hasbani, J., Hasbani, E., & Prado, A. D. (2022) · Journal of Cardiovascular Echography · doi:10.4103/jcecho.jcecho_138_20 · Cited by 4
Yoshida, Y., Jin, Z., Nakanishi, K., Matsumoto, K., Homma, S., Mannina, C. M., Shames, S., Elkind, M. S. V., Rundek, T., & Tullio, M. R. D. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.030274 · Cited by 5
Gao, Y., Li, B., Ma, Y., Liang, S., Yu, A., Zhang, H., & Guo, Z. (2024) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2024.101111 · Cited by 4
Ren, Y., Li, S., Chen, Y. C., Zhuang, B., Chen, W., & Xu, L. (2025) · International Journal of Cardiology · doi:10.1016/j.ijcard.2025.133391 · Cited by 4
Pianca, E. G., Foppa, M., Schmitz, G. B., Cañón-Montañéz, W., Duncan, B. B., & Santos, Â. B. S. (2025) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20240634i · Cited by 4
Wei, F., Xue, R., Wu, Y., Liang, W., He, X., Zhou, Y., Owusu‐Agyeman, M., Wu, Z., Zhu, W., He, J., et al. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.579400 · Cited by 4
Heart Failure with Perserved Ejection Fraction Current Diagnostic and Therapeutic Approaches
Shchendrygina, A., Zhbanov, K. A., Privalova, E. V., Yusupova, A. O., Danilogorskaya, Y. A., Salakheeva, E. Y., Sokolova, I. Y., Tsatsurova, S. A., Ageeva, A. A., & Belenkov, Y. N. (2021) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2021-05-01 · Cited by 4
Coiro, S., Huttin, O., Kobayashi, M., Lamiral, Z., Simonovic, D., Zannad, F. M., Rossignol, P., & Girerd, N. (2022) · Heart Failure Reviews · doi:10.1007/s10741-022-10266-2 · Cited by 4
Zhang, W., Azibani, F., Libhaber, E. N., Nankabirwa, J. I., Okello, E., Kayima, J., Ssinabulya, I., & Sliwa, K. S. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.966230 · Cited by 4
Santos, A. C. M., de Melo, E. V., Sousa, A. C. S., Oliveira, J. L. M., Martins‐Filho, P. R., Noronha, N. C. M., do Nascimento, C. I. S., & Campos, M. D. S. B. (2024) · Cardiology · doi:10.1159/000538522 · Cited by 4
Boulestreau, R., Crémer, A., Delarche, N., & Gosse, P. (2018) · Annales de Cardiologie et d Angéiologie · doi:10.1016/j.ancard.2018.08.007 · Cited by 4
Myocardial Strain and Dyssynchrony
Olsen, F. J., & Biering‐Sørensen, T. (2019) · Heart Failure Clinics · doi:10.1016/j.hfc.2018.12.002 · Cited by 4
Ovchinnikov, A. G., Potekhina, A. V., Ibragimova, N. M., Barabanova, E. A., Yushchyuk, E. N., & Ageev, F. T. (2019) · Kardiologiia · doi:10.18087/cardio.n394 · Cited by 4
Global longitudinal strain imaging and its utility in assessing risk in early stages of hypertension
Mani, A. (2019) · Journal of Clinical Hypertension · doi:10.1111/jch.13703 · Cited by 4
Kitada, S., Kawada, Y., Osaga, S., Kato, M., Kikuchi, S., Wakami, K., Seo, Y., & Ohte, N. (2020) · Heart and Vessels · doi:10.1007/s00380-020-01641-w · Cited by 4
The effect of spironolactone on diastolic function in haemodialysis patients
Hauser, T. G., Dornberger, V., Malzahn, U., Grebe, S. J., Liu, D., Störk, S., Nauck, M. A., Friedrich, N., Dörr, M., Wanner, C., et al. (2021) · International journal of cardiac imaging · doi:10.1007/s10554-021-02176-5 · Cited by 4
Fu, M., Hu, X., Sun, S., Yi, S., Zhang, Y., Feng, Y., Zhou, Y., Geng, Q., & Dong, H. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s310414 · Cited by 4
Paulus, W. J. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.03.016 · Cited by 4
Non-Invasive Hemodynamic Assessment of Heart Failure With Preserved Ejection Fraction
Istrătoaie, S., Frost, C. L., & Donal, E. (2025) · Korean Circulation Journal · doi:10.4070/kcj.2024.0370 · Cited by 3
Current Challenges for the Diagnosis of HFpEF and Possible Simplification of the Diagnostic Approach
Bernardi, M., Golino, M., Spadafora, L., Sarto, G., Forte, M., Simeone, B., Rocco, E., Valenti, V., Schiavon, S., Esposito, A., et al. (2025) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001755 · Cited by 3
Weisel, C. L., Dyke, C., Klug, M. G., Haldis, T., & Basson, M. D. (2022) · World Journal of Cardiology · doi:10.4330/wjc.v14.i5.307 · Cited by 3
Li, H., Chen, Z., Kahn, A. M., Kligerman, S. J., Narayan, H. K., & Contijoch, F. J. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1009445 · Cited by 3
Levitskaya, E. S., Batyushin, М. М., Zakusilov, D. I., & Batiushina, A. M. (2024) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2024-4063 · Cited by 3
Myocardial contraction fraction predicts outcomes in patients enrolled in the TOPCAT trial
Davis, B. J., Kim, M., Burton, Y., Elman, M., Hodovan, J., Shah, A. M., Maurer, M. S., Solomon, S. D., & Masri, A. (2025) · International Journal of Cardiology · doi:10.1016/j.ijcard.2025.133038 · Cited by 3
Self-citationLeft Ventricular Ejection Fraction in Patients With Acute Heart Failure: A Limited Tool?
Kalogeropoulos, A. P., & Butler, J. (2017) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2016.11.029 · Cited by 3
Pratap, B., Kallur, K. R., & Argulian, E. (2017) · Echocardiography · doi:10.1111/echo.13532 · Cited by 3
Das, K. M., Baskaki, U. M. A., Pulinchani, A., Ali, H. M., Mansoori, T. A., Gorkom, K., Das, A., Dewedar, H., & Sharma, S. (2022) · Diagnostics · doi:10.3390/diagnostics12081920 · Cited by 3
Jyotsna, M. (2022) · Indian Journal of Cardiovascular Disease in Women · doi:10.25259/mm_ijcdw_482 · Cited by 4
The effect of increased plasma potassium on myocardial function; a randomized POTCAST substudy
Winsløw, U., Sakthivel, T., Zheng, C., Philbert, B. T., Vinther, M., Frandsen, E., Iversen, K. K., Bundgaard, H., Jøns, C., & Risum, N. (2023) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-023-02914-x · Cited by 3
Inversion of Left Ventricular Axial Shortening: In Silico Proof of Concept for Treatment of HFpEF
Goetz, W. A., Yao, J., Brener, M. I., Puri, R., Swaans, M. J., Schopka, S., Wiesner, S., Creutzenberg, M., Sievert, H., & Kassab, G. S. (2024) · Bioengineering · doi:10.3390/bioengineering11070676 · Cited by 3
Kalogeropoulos, A. P., & Butler, J. (2017) · Revista Española de Cardiología · doi:10.1016/j.recesp.2016.11.022 · Cited by 3
Echocardiographic Measures of Strain and Prognosis
Huynh, Q. L., & Marwick, T. H. (2016) · Cardiovascular Innovations and Applications · doi:10.15212/cvia.2016.0057 · Cited by 3
Nuritdinov, N., & Kamilova, U. K. (2020) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2020-2464 · Cited by 3
Langer, N., Escher, A., Ozturk, C., Stephens, A., Roche, E. T., Granegger, M., Kaye, D. M., & Gregory, S. D. (2025) · Annals of Biomedical Engineering · doi:10.1007/s10439-025-03821-z · Cited by 2
Quantification of exercised-induced myocardial deformation with exercise CMR
Morales, M. A., Ghanbari, F., Rodriguez, J., Gopal, D. M., Waxman, A. B., Manning, W. J., & Nezafat, R. (2025) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2025.101987 · Cited by 2
Inter‐vendor variability and reproducibility of subcostal left ventricular longitudinal strain
Gong, F. F., Nishtala, A., Chow, K. Y., Jafari, L., Azizuddin, A., Ramirez, H. M., Chuzi, S. E., & Akhter, N. (2021) · International journal of cardiac imaging · doi:10.1007/s10554-020-02152-5 · Cited by 2
Ravnkilde, K., Skaarup, K. G., Grove, G. L., Modin, D., Nielsen, A. B., Falsing, M. M., Iversen, A. Z., Pedersen, S., Fritz‐Hansen, T., Galatius, S., et al. (2021) · International journal of cardiac imaging · doi:10.1007/s10554-021-02296-y · Cited by 2
Self-citationYoussef, A. A., Pfluecke, C., Dawid, M., Ibrahim, K. S., Günther, M., Kolschmann, S., Richter, U., Francke, A., Wunderlich, C., & Christoph, M. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-02429-0 · Cited by 2
Wang, S., Chen, A., & Duan, X. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.915918 · Cited by 2
Li, Q., Zhong, H., Yu, S., Cheng, Y., Dai, Y., Huang, F., Lin, Z., & Zhu, P. (2022) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.28373 · Cited by 2
Multimodality imaging in decompensated heart failure
D’Andrea, A., Ilardi, F., Palermi, S., Riegler, L., Miele, T., Giallauria, F., D’Alto, M., Russo, V., & Cice, G. (2023) · European Heart Journal Supplements · doi:10.1093/eurheartjsupp/suad052 · Cited by 2
Iwakura, K., Onishi, T., Koyama, Y., Iwamoto, M., Watanabe, S., Tanaka, K., Hirao, Y., Tanaka, N., Sumiyoshi, A., Okada, M., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-49664-3 · Cited by 2
The role of phosphodiesterase 9A inhibitors in heart failure
Foroshani, S., Karp, A., Aronow, W. S., & Lanier, G. M. (2024) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2024.2349813 · Cited by 2
Novel Techniques, Biomarkers and Molecular Targets to Address Cardiometabolic Diseases
Fiore, V. D., Cappelli, F., Punta, L. D., Biase, N. D., Armenia, S., Maremmani, D., Lomonaco, T., Biagini, D., Lenzi, A., Mazzola, M., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13102883 · Cited by 3
Nojiri, A., Morimoto, S., Fukuro, E., Okuyama, T., Anan, I., Kawai, M., Sakurai, K., Kobayashi, M., Kobayashi, H., Ida, H., et al. (2024) · Circulation Journal · doi:10.1253/circj.cj-24-0509 · Cited by 2
Diagnosis and management of diastolic dysfunction in arterial hypertension
Blanch, P., & Freixa‐Pamias, R. (2025) · Hipertensión y Riesgo Vascular · doi:10.1016/j.hipert.2025.06.002 · Cited by 3
O’Kelly, A. C., & Lau, E. S. (2020) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-020-00856-4 · Cited by 2
Donal, E., Galli, E., Hubert, A., & Bouzillé, G. (2017) · The Journal of Physiology · doi:10.1113/jp274108 · Cited by 2
Invasive Hemodynamic Assessment in Heart Failure With Preserved Ejection Fraction
Obokata, M., & Borlaug, B. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-64067-1.00008-5 · Cited by 2
Taamallah, K., Besbes, B., Raddaoui, H., Hajlaoui, N., Lahidheb, D., & Fehri, W. (2021) · PubMed Central · Cited by 2
Ionac, I., Lazăr, M.-A., Șoșdean, R., Văcărescu, C., Simonescu, M., Luca, C. T., & Mornoş, C. (2023) · Diagnostics · doi:10.3390/diagnostics13040745 · Cited by 2
On Books, Covers, and Judgments in Heart Failure
Borlaug, B. A., & Velazquez, E. J. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.08.021 · Cited by 2
Devices for heart failure with preserved ejection fraction
Langer, N., Dowsley, K., Kaye, D. M., & Gregory, S. D. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-22148-4.00007-1 · Cited by 1
Cardiac Computed Tomography: Technological Developments and Clinical Applications
Suzuki, K., Takaoka, H., Irie, R., Matsumoto, M., Noguchi, Y., Aoki, S., Yoshida, K., Matsumoto, H., Yashima, S., Kinoshita, M., et al. (2025) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd12120473 · Cited by 1
Barros, F. C., de Cezaro, J. C., Pianca, E. G., Menegazzo, W. R., Scolari, F. L., & da Silveira, A. D. (2025) · ABC Heart Failure & Cardiomyopathy · doi:10.36660/abc.20250014i · Cited by 1
Yang, D., Zhai, S., Ma, J., & Shi, F. (2026) · Medicine · doi:10.1097/md.0000000000048603 · Cited by 1
Understanding HFpEF Through Imaging
Harada, T., Naser, J. A., Ghanbari, F., & Borlaug, B. A. (2026) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2026.05.017 · Cited by 2
Sildenafil, Unbridled Optimism, and Heart Failure with Preserved Ejection Fraction
Reddy, Y. N. V., & Borlaug, B. A. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.690 · Cited by 1
Szyszka, A. (2019) · Choroby Serca i Naczyń · doi:10.5603/chsin.2019.0001 · Cited by 1
The Role of Echocardiography in Heart Failure Today
Pinto, J., & Koshy, A. G. (2021) · Journal of The Indian Academy of Echocardiography & Cardiovascular Imaging · doi:10.4103/jiae.jiae_20_20 · Cited by 1
Left ventricular ejection fraction: how to improve an established index?
Mesquita, C. T. (2021) · International journal of cardiac imaging · doi:10.1007/s10554-021-02199-y · Cited by 1
Sutil‐Vega, M., Rizzo, M., Taibi-Hajjami, F., Roca-Guerrero, C., Asenjo, I. C., Surribas, M. L., Vila, N., Ruiz, G. T., Flores, P. N., & Martínez‐Rubio, A. (2022) · Medical Research Archives · doi:10.18103/mra.v10i9.3035 · Cited by 1
Li, Q., Gao, X., Zhou, Z., Zhang, H., Li, W., Gao, Y., Bo, K., Wang, H., Wang, R., Sun, Z., et al. (2023) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims-22-1119 · Cited by 1
Reversibility of Cardiac Remodeling in Hypertensive Patients with Heart Failure
Paini, A., Rosei, C. A., Ciuceis, C. D., Salvetti, M., & Muiesan, M. L. (2023) · Updates in hypertension and cardiovascular protection · doi:10.1007/978-3-031-39315-0_22 · Cited by 2
He, J., Yang, W., Wu, W., Yin, G., Zhuang, B., Xu, J., Zhou, D., Zhang, J., Wang, Y., Zhu, L., et al. (2024) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.230281 · Cited by 1
Goetz, W. A., Brener, M. I., Puri, R., Swaans, M., Schopka, S., Wiesner, S., Creuztenberg, M., Sievert, H., Kassab, G. S., & Yao, J. (2024) · Bioengineering · doi:10.3390/bioengineering11060603 · Cited by 1
Cardiomyopathy with Subclinical Heart Failure
Contractor, H., Singh, K., & von Schwarz, E. (2024) · Cardiology and cardiovascular medicine. · doi:10.5772/intechopen.1005627 · Cited by 1
Imaging Advances in Heart Failure
Thamman, R., Hosseini, N., Dikou, M.-L., Hassan, I. U., Marchenko, O. Y., Abiola, O., & Grapsa, J. (2024) · Cardiac failure review · doi:10.15420/cfr.2023.10 · Cited by 1
Goeddel, L. A., Navarrete, S., Waldron, N., D'Amiano, A. J., Faraday, N. R., Lima, J. A. C., Parikh, C. R., Bandeen‐Roche, K., Hays, A. G., & Brown, C. H. (2024) · Cardiology · doi:10.1159/000541725 · Cited by 1
Ohno, M., Segawa, T., Noda, T., Yasuda, Y., & Yamamoto, J. (2025) · BMC Nephrology · doi:10.1186/s12882-025-04368-w · Cited by 1
Recalde, J. F. C., & Lacambra, I. (2017) · Revista Ecuatoriana de Medicina y Ciencias Biológicas · doi:10.26807/remcb.v38i2.550 · Cited by 1
Utilidad del “speckle tracking” en pacientes no oncológicos
Barrera-Avellaneda, C., Paz, M. A., & Salazar, J. S. (2019) · Revista Colombiana de Cardiología · doi:10.1016/j.rccar.2018.10.017 · Cited by 1
Жерко, О. М., & Шкребнева, Э. И. (2021) · Medical Visualization · doi:10.24835/1607-0763-939 · Cited by 1
The impact of medical therapy on left ventricular strain: Current state and future perspectives
Карев, Е. А., Verbilo, S. L., Malev, E. G., & Прокудина, М. Н. (2022) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23244 · Cited by 1
Cell Therapy for Heart Failure With Preserved Ejection Fraction
Borlaug, B. A., & Reddy, Y. N. V. (2016) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2016.01.004 · Cited by 1
Kosmala, W. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.05.024 · Cited by 1
Piecing together the puzzle of sex‐specific differences in left ventricular ejection fraction
Olsen, F. J., Solomon, S. D., & Biering‐Sørensen, T. (2021) · European Journal of Heart Failure · doi:10.1002/ejhf.2127 · Cited by 1
Self-citationChen, J., Li, H., Hao, B., Cai, Y., Wang, S., & Liu, H. (2021) · Research Square · doi:10.21203/rs.3.rs-430111/v1 · Cited by 1
Walking the Line Between Failure and Remission
Čikeš, M., & Solomon, S. D. (2021) · JACC Heart Failure · doi:10.1016/j.jchf.2021.10.006 · Cited by 1
Self-citation(2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa987 · Cited by 1
Ventricular Remodeling in Heart Failure
Aquila, I., & Shah, A. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.10903-2 · Cited by 1
Self-citationShi, Y., Wang, Q., Liu, C., Xiong, S., Yang, C., Qiao, W., Dong, G., & Liu, J. (2023) · medRxiv · doi:10.1101/2023.03.13.23287207 · Cited by 1
Peigh, G., & Patel, R. B. (2023) · European Journal of Heart Failure · doi:10.1002/ejhf.2872 · Cited by 1
Vakilian, F., Ghaderi, F., & Hedayatabad, F. H. (2016) · DOAJ (DOAJ: Directory of Open Access Journals)
Boulestreau, R., Crémer, A., & Gose, P. (2016) · Annales d Endocrinologie · doi:10.1016/j.ando.2016.07.140
The Role of Echocardiography in the Detection of Chemotherapy-Induced Cardiotoxicities
Gleason, P. T., Lisko, J. C., & Lerakis, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803547-4.00032-x
Management of Advanced Heart Failure in a Cancer Patient
Lajoie, A. C., Dunhill, J., & Hamilton, M. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803547-4.00020-3
Heart Failure and Hypertension
Kuznetsova, T., & Cauwenberghs, N. (2016) · Springer eBooks · doi:10.1007/978-3-319-45237-1_21
Ikonomidis, I., Vlastos, D., & Parissis, J. (2017) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jex025
OBSOLETE: Ventricular Remodeling in Heart Failure
Shah, A. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.10903-1
Self-citation
Metadata
- Authors
- Shah, A. M., Claggett, B., Sweitzer, N. K., Shah, S. J., Anand, I. S., Liu, L., Pitt, B., Pfeffer, M. A., & Solomon, S. D.
- Affiliations
- Northwestern University (US)
- ORCID
- Venue
- Circulation
- Published
- 2015-08-04
- Volume
- 132
- Issue
- 5
- Pages
- 402-414
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC4526442
- OpenAlex
- W2105400632
- Cited by
- 478
- References
- 60
- Citations by year
- 2026: 14 · 2025: 33 · 2024: 36 · 2023: 45 · 2022: 63 · 2021: 52 · 2020: 59 · 2019: 47 · 2018: 37 · 2017: 41 · 2016: 39 · 2015: 9
- FWCI
- 30.57
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Health and Human Services (HHSN268201100007C, HHSN268201100012C, HHSN268201100005C, HHSN268201100008C, HHSN268201100006C, HHSN268201100010C, HHSN268201100011C, HHSN268201100009C)
- American Heart Association (HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, 14CRP20380422, HHSN268201100012C, HHSN268201100005C, HHSN268201100009C, HHSN268201100011C, HHSN268201100010C)
- National Heart, Lung, and Blood Institute (HHSN268201 100012C, HHSN268201100007I, HHSN268201100007C, HHSN2682 01100008C, HH-SN-268201100006C, HHSN268201100011C, HHSN2682011-00005I, HHSN2682011-00009I, HHSN268201100005C, HHSN268201100005G, HHSN268201100010C, HHSN268201100011I, HHSN26820 1100009C, K08HL116792, HHSN2682011-00008I, HHSN268200425207C)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- heart failure with preserved ejection fraction, left ventricular systolic function, left ventricular longitudinal strain, spironolactone, prognosis, cardiovascular mortality, heart failure hospitalization, speckle tracking echocardiography, imaging biomarkers, TOPCAT trial, mineralocorticoid receptor antagonists
- MeSH terms
- Aged, Aged, 80 and over, Mineralocorticoid Receptor Antagonists, Double-Blind Method, Electrocardiography, Female, Follow-Up Studies, Heart Arrest, Hospitalization, Humans, Male, Middle Aged, Prognosis, Spironolactone, Stroke Volume, Incidence, Survival Rate, Treatment Outcome, Ventricular Dysfunction, Left, Internationality, Heart Failure, Systolic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
