The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Mechanisms, Consequences, and Prevention of Coronary Graft Failure
Open accessAbstract
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein review relevant current evidence to give an overview of the incidence, pathophysiology, and clinical consequences of this multifactorial phenomenon. Thrombosis, endothelial dysfunction, vasospasm, and oxidative stress are different mechanisms associated with graft failure. Intrinsic morphological and functional features of the bypass conduits play a role in determining failure. Similarly, characteristics of the target coronary vessel, such as the severity of stenosis, the diameter, the extent of atherosclerotic burden, and previous endovascular interventions, are important determinants of graft outcome and must be taken into consideration at the time of surgery. Technical factors, such as the method used to harvest the conduits, the vasodilatory protocol, the storage solution, and the anastomotic technique, also play a major role in determining graft success. Furthermore, systemic atherosclerotic risk factors, such as age, sex, diabetes mellitus, hypertension, and dyslipidemia, have been variably associated with graft failure. The failure of a coronary graft is not always correlated with adverse clinical events, which vary according to the type, location, and reason for failed graft. Intraoperative flow verification and secondary prevention using antiplatelet and lipid-lowering agents can help reducing the incidence of graft failure.
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Self-citationTicagrelor versus clopidogrel in patients with acute coronary syndromes
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Self-citationPlatelet Activation and Atherothrombosis
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Self-citationInterpretation of the evidence for the efficacy and safety of statin therapy
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On-Pump versus Off-Pump Coronary-Artery Bypass Surgery
Shroyer, A. L., Grover, F. L., Hattler, B., Collins, J. F., McDonald, G. O., Kozora, E., Lucke, J. C., Baltz, J. H., & Novitzky, D. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0902905 · Cited by 1,148
Metadata
- Authors
- Gaudino, M., Antoniades, C., Benedetto, U., Deb, S., Di Franco, A., Di Giammarco, G., Fremes, S., Glineur, D., Grau, J., He, G.-W., Marinelli, D., Ohmes, L. B., Patrono, C., Puskas, J., Tranbaugh, R., Girardi, L. N., Taggart, D. P., Ruel, M., & Bakaeen, F. G.
- Venue
- Circulation
- Published
- 2017-10-31
- Volume
- 136
- Issue
- 18
- Pages
- 1749-1764
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2765697464
- Cited by
- 355
- References
- 64
- FWCI
- 20.97
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Gaudino, M., Antoniades, C., Benedetto, U., Deb, S., Di Franco, A., Di Giammarco, G., Fremes, S., Glineur, D., Grau, J., He, G.-W., Marinelli, D., Ohmes, L. B., Patrono, C., Puskas, J., Tranbaugh, R., Girardi, L. N., Taggart, D. P., Ruel, M., & Bakaeen, F. G. (2017). Mechanisms, Consequences, and Prevention of Coronary Graft Failure. Circulation. https://doi.org/10.1161/circulationaha.117.027597
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
