The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Long-Term Follow-Up of Individuals With the Electrocardiographic Pattern of Right Bundle-Branch Block and ST-Segment Elevation in Precordial Leads V 1 to V 3
Abstract
Background — The electrocardiographic pattern of right bundle-branch block with ST-segment elevation in leads V 1 to V 3 is increasingly recognized among patients who have aborted sudden cardiac death, but also in asymptomatic individuals, raising questions about its prognostic significance. Methods and Results — The clinical, electrophysiological, and follow-up data of 334 patients with the Brugada phenotype were analyzed. A total of 79 women and 255 men with a mean age at diagnosis of 42±16 years were studied. The abnormal ECG was recognized after a resuscitated cardiac arrest in 71 patients (group A), after a syncopal episode in 73 patients (group B), and in 190 asymptomatic individuals (group C). Sustained ventricular arrhythmias were inducible in 83%, 63%, and 33% of patients in group A, group B, and group C, respectively. During 54±54 and 26±36 months of follow-up, respectively, 62% of patients in group A and 19% of group B patients had a new arrhythmic event. Inducibility of ventricular arrhythmias was the only predictor of arrhythmia occurrence in both groups. During a mean follow-up of 27±29 months, 8% of group C individuals had a first arrhythmic event. In these individuals, inducibility of ventricular arrhythmias and a basal abnormal ECG were predictors of arrhythmia occurrence. Conclusions — An ECG showing right bundle-branch block and ST-segment elevation in the right precordial leads is a marker of malignant ventricular arrhythmias and sudden death. Recurrence of malignant arrhythmias is high after the occurrence of symptoms. Among asymptomatic individuals, those with a spontaneously abnormal ECG and inducible to ventricular arrhythmias have the poorer prognosis.
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Cites
Brugada, P., & Brugada, J. (1992) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(92)90253-j · Cited by 3,331
Self-citationYan, G.-X., & Antzelevitch, C. (1999) · Circulation · doi:10.1161/01.cir.100.15.1660 · Cited by 1,126
Self-citationA NEW FAMILIAL CARDIAC SYNDROME IN CHILDREN.
Ward, O. C. (1964) · PubMed · Cited by 826
Brugada, R., Brugada, J., Antzelevitch, C., Kirsch, G. E., Potenza, D., Towbin, J. A., & Brugada, P. (2000) · Circulation · doi:10.1161/01.cir.101.5.510 · Cited by 772
Self-citationMiyazaki, T., Mitamura, H., Miyoshi, S., Soejima, K., Aizawa, Y., & Ogawa, S. (1996) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00613-3 · Cited by 764
Brugada, J., Brugada, R., & Brugada, P. (1998) · Circulation · doi:10.1161/01.cir.97.5.457 · Cited by 713
Self-citationDumaine, R., Towbin, J. A., Brugada, P., Vatta, M., Nesterenko, D. V., Nesterenko, V. V., Brugada, J., Brugada, R., & Antzelevitch, C. (1999) · Circulation Research · doi:10.1161/01.res.85.9.803 · Cited by 601
Self-citationPriori, S. G., Napolitano, C., Gasparini, M., Pappone, C., Della Bella, P., Brignole, M., Giordano, U., Giovannini, T., Menozzi, C., Bloise, R., et al. (2000) · Circulation · doi:10.1161/01.cir.102.20.2509 · Cited by 457
Prevalence of the Brugada syndrome in an apparently healthy population
Hermida, J.-S., Lemoine, J.-L., Aoun, F. B., Jarry, G., Rey, J.-L., & Quiret, J.-C. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00835-3 · Cited by 246
Fontaine, G. H. (1977) · Medical Entomology and Zoology · Cited by 235
Cited by
Priori, S. G., Wilde, A. A., Horie, M., Cho, Y., Behr, E. R., Berul, C., Blom, N., Brugada, J., Chiang, C.-E., Huikuri, H., et al. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.05.014 · Cited by 1,942
Self-citationSudden Death in Young Athletes
Maron, B. J. (2003) · New England Journal of Medicine · doi:10.1056/nejmra022783 · Cited by 1,394
Probst, V., Veltmann, C., Eckardt, L., Meregalli, P. G., Gaita, F., Tan, H. L., Babuty, D., Sacher, F., Giustetto, C., Schulze-Bahr, E., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.887026 · Cited by 847
Short QT Syndrome: A Familial Cause of Sudden Death
Gaita, F., Giustetto, C., Bianchi, F., Wolpert, C., Schimpf, R., Riccardi, R., Grossi, S., Richiardi, E., & Borggrefe, M. (2003) · Circulation · doi:10.1161/01.cir.0000085071.28695.c4 · Cited by 708
Priori, S. G., Wilde, A. A., Horie, M., Cho, Y., Behr, E. R., Berul, C., Blom, N., Brugada, J., Chiang, C.-E., Huikuri, H., et al. (2013) · EP Europace · doi:10.1093/europace/eut272 · Cited by 624
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Metadata
- Authors
- Brugada, J., Brugada, R., Antzelevitch, C., Towbin, J., Nademanee, K., & Brugada, P.
- Venue
- Circulation
- Published
- 2002-01
- Volume
- 105
- Issue
- 1
- Pages
- 73-78
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2083594415
- Cited by
- 630
- References
- 11
- FWCI
- 33.22
- Type
- journal article
- Language
- en
- Open access
- closed
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