The DOI matches its Crossref record.
Effects of Long-Term Biventricular Stimulation for Resynchronization on Echocardiographic Measures of Remodeling
Abstract
Background — Long-term ventricular resynchronization therapy improves symptom status. Changes in left ventricular remodeling have not been adequately evaluated. Methods and Results — Fifty-three patients with systolic heart failure and bundle-branch block underwent implantation of biventricular stimulation (BVS) devices as part of a randomized trial. Echocardiograms were acquired at randomization and at 6-week intervals until completion of 12 weeks of continuous BVS. There were no changes in heart rate or QRS duration after 12 weeks of BVS. Serum norepinephrine values did not change with BVS. After 12 weeks of BVS, left atrial volume decreased. Left ventricular end-systolic and end-diastolic dimensions and left ventricular end-systolic volume also decreased after 12 weeks of BVS. Sphericity index did not change. Measures of systolic function, including left ventricular outflow tract and aortic velocity time integral and myocardial performance index, improved. Conclusions — Long-term resynchronization therapy results in atrial and ventricular reverse remodeling and improved hemodynamics.
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Cited by
Bristow, M. R., Saxon, L. A., Boehmer, J., Krueger, S., Kass, D. A., De Marco, T., Carson, P., DiCarlo, L., DeMets, D., White, B. G., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032423 · Cited by 5,812
Self-citationBradley, D. J., Bradley, E. A., Baughman, K. L., Berger, R. D., Calkins, H., Goodman, S. N., Kass, D. A., & Powe, N. R. (2003) · JAMA · doi:10.1001/jama.289.6.730 · Cited by 710
Breithardt, O. A., Sinha, A. M., Schwammenthal, E., Bidaoui, N., Markus, K. U., Franke, A., & Stellbrink, C. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02937-6 · Cited by 517
St John Sutton, M. G., Plappert, T., Hilpisch, K. E., Abraham, W. T., Hayes, D. L., & Chinchoy, E. (2006) · Circulation · doi:10.1161/circulationaha.104.520817 · Cited by 361
Solomon, S. D., Foster, E., Bourgoun, M., Shah, A., Viloria, E., Brown, M. W., Hall, W. J., Pfeffer, M. A., & Moss, A. J. (2010) · Circulation · doi:10.1161/circulationaha.110.955039 · Cited by 339
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Metadata
- Authors
- Saxon, L. A., De Marco, T., Schafer, J., Chatterjee, K., Kumar, U. N., & Foster, E.
- Venue
- Circulation
- Published
- 2002-03-19
- Volume
- 105
- Issue
- 11
- Pages
- 1304-1310
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2033857855
- Cited by
- 292
- References
- 0
- FWCI
- 20.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- Saxon, L. A., De Marco, T., Schafer, J., Chatterjee, K., Kumar, U. N., & Foster, E. (2002). Effects of Long-Term Biventricular Stimulation for Resynchronization on Echocardiographic Measures of Remodeling. Circulation. https://doi.org/10.1161/hc1102.105730
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