The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Are ACE Inhibitors a “Magic Bullet” Against Oxidative Stress?
Abstract
Outcomes Prevention Eval- uation (HOPE) study, 1,2 as well as the Study to Evaluate Carotid Ultrasound Changes in Patients Treated With Ramipril and Vitamin E (SECURE), 3 demonstrated that treatment with an ACE inhibitor but not vitamin E had beneficial effects on the prognosis and progression of atherosclerosis.In these studies, long-term ACE inhibition significantly reduced the rate of death, myocardial infarction, and stroke and reduced the intima-to-media ratio of carotid arteries in patients at high risk for cardiovascular events.It is likely that these findings will have wide-ranging implications for the treatment of cardiovascular disease, and the contrasting results with respect to ACE inhibitors and vitamin E provide an opportunity to revisit the role of oxidative stress in vascular disease.
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Citations
Cites
(2000) · New England Journal of Medicine · doi:10.1056/nejm200001203420301 · Cited by 8,663
Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients
(2000) · New England Journal of Medicine · doi:10.1056/nejm200001203420302 · Cited by 1,957
Salonen, J. T., Nyyssönen, K., Salonen, R., Lakka, H. ‐., Kaikkonen, J., Porkkala‐Sarataho, E., Voutilainen, S., Lakka, T. A., Rissanen, T., Leskinen, L., et al. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00752.x · Cited by 327
Cited by
The clinical implications of endothelial dysfunction
Widlansky, M. E., Gokce, N., Keaney, J. F., & Vita, J. A. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00994-x · Cited by 1,749
Self-citationCeriello, A., & Motz, E. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000122852.22604.78 · Cited by 1,378
A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation
Erickson, J. R., Joiner, M.-L. A., Guan, X., Kutschke, W., Yang, J., Oddis, C. V., Bartlett, R. K., Lowe, J. S., O'Donnell, S. E., Aykin-Burns, N., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.048 · Cited by 1,122
Ceriello, A. (2003) · Diabetes Care · doi:10.2337/diacare.26.5.1589 · Cited by 734
The role of oxidative stress in the pathophysiology of hypertension
Rodrigo, R., González, J., & Paoletto, F. (2011) · Hypertension Research · doi:10.1038/hr.2010.264 · Cited by 436
Metadata
- Authors
- Münzel, T., & Keaney, J. F.
- Venue
- Circulation
- Published
- 2001-09-25
- Volume
- 104
- Issue
- 13
- Pages
- 1571-1574
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2070763907
- Cited by
- 226
- References
- 3
- FWCI
- 9.03
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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