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Cited by 734

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of Age

Open access
Meaume, S., Benetos, A., Henry, O.F., Rudnichi, A., Safar, M.E.·2001·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

Aortic pulse wave velocity (PWV) is a significant and independent predictor of cardiovascular mortality in subjects with essential hypertension and in patients with end-stage renal disease. Its contribution to cardiovascular risk in subjects 70 to 100 years old has never been tested. A cohort of 141 subjects (mean±SD age, 87.1±6.6 years) was studied in 3 geriatrics departments in a Paris suburb. Together with sphygmomanometric blood pressure measurements, aortic PWV was measured with a validated automatic device. During the 30-month follow-up, 56 patients died (27 from cardiovascular events). Logistic regressions indicated that age ( P =0.005) and a loss of autonomy ( P =0.01) were the best predictors of overall mortality. For cardiovascular mortality, aortic PWV was the major risk predictor ( P =0.016). The odds ratio was 1.19 (95% confidence interval, 1.03 to 1.37). Antihypertensive drug treatment and blood pressure, including systolic and pulse pressure, had no additive role. In subjects 70 to 100 years old, aortic PWV is a strong, independent predictor of cardiovascular death, whereas systolic or pulse pressure was not. This prospective result will need to be confirmed in an intervention trial.

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Metadata

Authors
Meaume, S., Benetos, A., Henry, O. F., Rudnichi, A., & Safar, M. E.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
2001-12
Volume
21
Issue
12
Pages
2046-2050
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W2120862290
Cited by
734
References
23
FWCI
14.74
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of Age. https://app.cochat.ai/papers/10.1161/hq1201.100226
The paper
Meaume, S., Benetos, A., Henry, O. F., Rudnichi, A., & Safar, M. E. (2001). Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of Age. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/hq1201.100226

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