The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of Age
Open accessAbstract
Aortic pulse wave velocity (PWV) is a significant and independent predictor of cardiovascular mortality in subjects with essential hypertension and in patients with end-stage renal disease. Its contribution to cardiovascular risk in subjects 70 to 100 years old has never been tested. A cohort of 141 subjects (mean±SD age, 87.1±6.6 years) was studied in 3 geriatrics departments in a Paris suburb. Together with sphygmomanometric blood pressure measurements, aortic PWV was measured with a validated automatic device. During the 30-month follow-up, 56 patients died (27 from cardiovascular events). Logistic regressions indicated that age ( P =0.005) and a loss of autonomy ( P =0.01) were the best predictors of overall mortality. For cardiovascular mortality, aortic PWV was the major risk predictor ( P =0.016). The odds ratio was 1.19 (95% confidence interval, 1.03 to 1.37). Antihypertensive drug treatment and blood pressure, including systolic and pulse pressure, had no additive role. In subjects 70 to 100 years old, aortic PWV is a strong, independent predictor of cardiovascular death, whereas systolic or pulse pressure was not. This prospective result will need to be confirmed in an intervention trial.
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Arterial Stiffness and Cardiovascular Events: The Framingham Heart Study
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Arterial Stiffness and Risk of Coronary Heart Disease and Stroke: The Rotterdam Study
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Metadata
- Authors
- Meaume, S., Benetos, A., Henry, O. F., Rudnichi, A., & Safar, M. E.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2001-12
- Volume
- 21
- Issue
- 12
- Pages
- 2046-2050
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2120862290
- Cited by
- 734
- References
- 23
- FWCI
- 14.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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