The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Dry-Weight Reduction in Hypertensive Hemodialysis Patients (DRIP): A Randomized, Controlled Trial
Open accessAbstract
Volume excess is thought to be important in the pathogenesis of hypertension among hemodialysis patients. To determine whether additional volume reduction will result in improvement in blood pressure (BP) among hypertensive patients on hemodialysis and to evaluate the time course of this response, we randomly assigned long-term hypertensive hemodialysis patients to ultrafiltration or control groups. The additional ultrafiltration group (n=100) had the dry weight probed without increasing time or duration of dialysis, whereas the control group (n=50) only had physician visits. The primary outcome was change in systolic interdialytic ambulatory BP. Postdialysis weight was reduced by 0.9 kg at 4 weeks and resulted in −6.9 mm Hg (95% CI: −12.4 to −1.3 mm Hg; P =0.016) change in systolic BP and −3.1 mm Hg (95% CI: −6.2 to −0.02 mm Hg; P =0.048) change in diastolic BP. At 8 weeks, dry weight was reduced 1 kg, systolic BP changed −6.6 mm Hg (95% CI: −12.2 to −1.0 mm Hg; P =0.021), and diastolic BP changed −3.3 mm Hg (95% CI: −6.4 to −0.2 mm Hg; P =0.037) from baseline. The Mantel-Hanzel combined odds ratio for systolic BP reduction of ≥10 mm Hg was 2.24 (95% CI: 1.32 to 3.81; P =0.003). There was no deterioration seen in any domain of the kidney disease quality of life health survey despite an increase in intradialytic signs and symptoms of hypotension. The reduction of dry weight is a simple, efficacious, and well-tolerated maneuver to improve BP control in hypertensive hemodialysis patients. Long-term control of BP will depend on continued assessment and maintenance of dry weight.
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“During the last two decades, HBPM has been used increasingly in clinical hypertension research [17,155,267–273].”
From Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension (2021) · cites this paper as [273]
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“During the last two decades, HBPM has been used increasingly in clinical hypertension research [17,155,267–273].”
From Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension (2021) · cites this paper as [269]
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Citations
Cites
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.
Go, A., Chertow, G., Fan, D., McCulloch, C., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1016/j.jvs.2004.10.020 · Cited by 11,645
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041031 · Cited by 11,369
Statistics in Medicine — Reporting of Subgroup Analyses in Clinical Trials
Wang, R., Lagakos, S. W., Ware, J. H., Hunter, D. J., & Drazen, J. M. (2007) · New England Journal of Medicine · doi:10.1056/nejmsr077003 · Cited by 1,445
Development of the Kidney Disease Quality of Life (KDQOLTM) Instrument
Hays, R. D., Kallich, J. D., Mapes, D., Coons, S. J., & Carter, W. B. (1994) · Quality of Life Research · doi:10.1007/bf00451725 · Cited by 1,235
Sympathetic Overactivity in Patients with Chronic Renal Failure
Converse, R. L., Jacobsen, T. N., Toto, R. D., Jost, C. M. T., Cosentino, F., Fouad-Tarazi, F., & Victor, R. G. (1992) · New England Journal of Medicine · doi:10.1056/nejm199212313272704 · Cited by 1,132
Guyton, A., Coleman, T. G., Cowley, A. W., Scheel, K., Manning, R., & Norman, R. A. (1972) · American Journal of Medicine · doi:10.1016/0002-9343(72)90050-2 · Cited by 1,110
Survival as an index of adequacy of dialysis.
Charra, B., Calemard, E., Ruffet, M., Chazot, C., Terrat, J., Vanel, T., & Laurent, G. (1992) · Kidney International · doi:10.1038/ki.1992.191 · Cited by 777 · cited 1×
“Angiotensin receptor blockers 19 (19) 4 (8)”
Culleton, B., Walsh, M., Klarenbach, S., Mortis, G., Scott-Douglas, N., Quinn, R., Tonelli, M., Donnelly, S., Friedrich, M., Kumar, A., et al. (2007) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.298.11.1291 · Cited by 708
Agarwal, R., Nissenson, A. R., BATLLE, D. C., Coyne, D. W., Trout, J. R., & Warnock, D. G. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(03)00366-8 · Cited by 480
Self-citationAssociation between pulse pressure and mortality in patients undergoing maintenance hemodialysis.
Klassen, P., Lowrie, E., Reddan, D., DeLong, E., Coladonato, J. A., Szczech, L., Lazarus, J., & Owen, W. (2002) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.287.12.1548 · Cited by 414
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Hypertension in Patients on Hemodialysis: Looking Beyond Stable Sessions
Jamboti, J., & Anupama, Y. (2024) · Indian Journal of Kidney Diseases · doi:10.4103/ijkd.ijkd_10_24
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Hausberg, M. (2022) · Die Nephrologie · doi:10.1007/s11560-022-00587-6
(2019) · The Upper Limit · doi:10.1515/9783110584066-022
Agarwal, R. (2018) · doi:10.7912/c2p948
Self-citationPathogenesis and treatment of hypertension in haemodialysis patients with chronic kidney disease
Pokora, P., Adamczak, M., & Więcek, A. (2017) · Arterial Hypertension · doi:10.5603/ah.a2017.0021 · Cited by 1
“The relation between dry-weight reduction and hypertension is well described in a randomized trial DRIP (Dry-Weight Reduction in Hypertensive Haemodialysis Patients) [59].”
BackgroundInfluentialHemodiyaliz Hastalarının Hipertansiyon Yönetimine İlişkin Evde Yaptıkları Uygulamalar
Gökdoğan, F., Kes, D., Turgay, G., & Tuna, D. (2017) · doi:10.5262/tndt.2017.1002.11
Blutdruckeinstellung und -medikation
Hausberg, M. (2016) · Dialyse aktuell · doi:10.1055/s-0042-118943
Elshamy, A., EL-Kashif, E. H., El-Gohary, E., Hashad, D., & Yousef, G. (2016) · doi:10.15406/unoaj.2016.03.00083
Come gestire l'ipertensione arteriosa in emodialisi?
Cavalli, A., & Pontoriero, G. (2015) · Giornale di Clinica Nefrologica e Dialisi · doi:10.33393/gcnd.2015.788
“L’altro cardine del trattamento dell’ipertensione arteriosa nell’emodializzato è rappresentato dalla riduzione del peso secco, che si può ritenere utile anche in quei soggetti che non presentano evidenti segni di ritenzione idrosodica (26).”
BackgroundHow is the Heart Best Protected in Chronic Dialysis Patients?
Chazot, C., & Jean, G. (2014) · Seminars in Dialysis · doi:10.1111/sdi.12179 · Cited by 1
“(34) obtained a more significant decline of systolic and diastolic BP in 100 HD patients who were probed for reduction in postdialysis BW during a 8-week period than in 50 control patients.”
BackgroundHYPERTENSION IN PATIENTS WITH RENAL PARENCHYMAL DISEASE, CHRONIC RENAL FAILURE, AND CHRONIC DIALYSIS
Rodicio, J., & García-Donaire, J. (2014) · doi:10.1201/b17072-45
Treatment of the Patient with End‐Stage Diabetic Nephropathy
Ghosn, M., & Ziyadeh, F. (2012) · doi:10.1002/9781118494073.ch16
Methoden zur Bestimmung des Trockengewichts
Wizemann, V. (2012) · Der Nephrologe · doi:10.1007/s11560-012-0638-7
van der Giet, M., & Tölle, M. (2010) · doi:10.1055/s-0030-1251465
Nutritional management of sodium, chloride, and water in kidney disease and kidney failure
Burnier, M. (2022) · Nutritional Management of Renal Disease · doi:10.1016/b978-0-12-818540-7.00038-0
Effect of dry body weight on intra-dialytic hypertension in patients on regular hemodialysis
Mohamed, E., Abdelkader, A., & Mostafa, M. H. (2022) · doi:10.53730/ijhs.v6ns1.5852
“, (9) noted that additional volume reduction would result in an improvement in blood pressure (BP) among hypertensive patients after hemodialysis (HD), despite these patients having well-controlled dry weights.”
BackgroundManagement of Hypertension in Pediatric Dialysis Patients
Wühl, E., & Flynn, J. (2021) · Springer eBooks · doi:10.1007/978-3-030-66861-7_31
Hypertension in End-Stage Renal Disease
Gupta, S., & Liebman, S. (2020) · Hypertension Journal · doi:10.15713/ins.johtn.0177
Hypertension in Dialysis Patients: Clinical Epidemiology, Pathogenesis, Diagnosis, and Treatment
Sarafidis, P. A., Georgianos, P. I., & Zoccali, C. (2018) · Updates in hypertension and cardiovascular protection · doi:10.1007/978-3-319-59918-2_24
Management of Hypertension in Patients with Chronic Kidney Disease and End-stage Renal Disease
Patel, M., & Gupta, A. K. (2018) · doi:10.15713/ins.johtn.0105
“dialysate sodium toward pre-dialysis sodium in selected individuals, and avoidance of sodium-containing or sodiumexchanging drugs.[81-83] Randomized trials clearly show that BP lowering is associated with reduced cardiovascular morbidity and mortality in dialysis patients.”
BackgroundVoroneanu, L. E., Siriopol, D. C., & Covic, A. C. (2017) · Springer eBooks · doi:10.1007/978-3-319-56827-0_11
Managing Blood Pressure in the Elderly: What Is Different?
Santos, S., Pazhayattil, G. S., & Peixoto, A. (2016) · doi:10.1007/978-1-4939-3320-4_7
“3 mmHg reduction in BP over a 2-month period [ 9 ].”
BackgroundHypertension in the Dialysis Patient
Sinha, A. D. (2016) · Springer eBooks · doi:10.1007/978-1-4939-6436-9_7
(2014) · Hypertension Research · doi:10.1038/hr.2014.17
Kidney Disease in Hypertension
Udani, S., Lazich, I., & Bakris, G. L. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-2766-1.00030-2
Metadata
- Authors
- Agarwal, R., Alborzi, P., Satyan, S., & Light, R. P.
- Affiliations
- Richard L. Roudebush VA Medical Center (US)
- Venue
- Hypertension
- Published
- 2009-03
- Volume
- 53
- Issue
- 3
- Pages
- 500-507
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- PMC
- PMC2679163
- OpenAlex
- W2115611820
- Cited by
- 349
- References
- 35
- Citations by year
- 2026: 7 · 2025: 15 · 2024: 12 · 2023: 17 · 2022: 19 · 2021: 22 · 2020: 21 · 2019: 19 · 2018: 20 · 2017: 22 · 2016: 22 · 2015: 26 · 2014: 20 · 2013: 16 · 2012: 32
- FWCI
- 20.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- IUScholarWorks (Indiana University) (submittedVersion)
- Funders
- Dialysis Clinics
- U.S. Public Health Service (5R01-NIDDK062030-05)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK062030)
- Topics
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
- Keywords
- dry weight reduction, ultrafiltration, blood pressure control, hypotension, quality of life, dialysis
- MeSH terms
- Adult, Aged, Blood Pressure, Diastole, Female, Renal Dialysis, Humans, Hypertension, Kidney Failure, Chronic, Male, Middle Aged, Prospective Studies, Quality of Life, Systole, Time Factors, Weight Loss, Hemodiafiltration
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