The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Day-Night Dip and Early-Morning Surge in Blood Pressure in Hypertension: Prognostic Implications
Abstract
We investigated the relationship between the day-night blood pressure (BP) dip and the early morning BP surge in an cohort of 3012 initially untreated subjects with essential hypertension. The day-night reduction in systolic BP showed a direct association with the sleep trough ( r =0.564; P <0.0001) and the preawakening ( r =0.554; P <0.0001) systolic BP surge. Over a mean follow-up period of 8.44 years, 268 subjects developed a major cardiovascular event (composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, and heart failure requiring hospitalization) and 220 subjects died. In a Cox model, after adjustment for predictive covariates, including age, sex, diabetes mellitus, cigarette smoking, total cholesterol, left ventricular hypertrophy on ECG, estimated glomerular filtration rate, and average 24-hour systolic BP, a blunted sleep trough (≤19.5 mm Hg; quartile 1) and preawakening (≤9.5 mm Hg; quartile 1) BP surge was associated with an excess risk of events (hazard ratio, 1.66 [95% CI, 1.14–2.42]; P =0.009; hazard ratio, 1.71 [95% CI, 1.12–2.71]; P =0.013). After adjustment for the same covariates, neither the dipping pattern nor the measures of early morning BP surge were independent predictors of mortality. In conclusion, in initially untreated subjects with hypertension, a blunted day-night BP dip was associated with a blunted morning BP surge and vice versa. In these subjects, a blunted morning BP surge was an independent predictor of cardiovascular events, whereas an excessive BP surge did not portend an increased risk of events.
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Regression Models and Life-Tables
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Circadian Variation in the Frequency of Onset of Acute Myocardial Infarction
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Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension.
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“008), whereas preawakening BP surge did not achieve significance.(4) In a general population study from Japan, Metoki et al(7) followed for an average of 10.”
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(2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,655
Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Umemura, S., Arima, H., Arima, S., Asayama, K., Dohi, Y., Hirooka, Y., Horio, T., Hoshide, S., Ikeda, S., Ishimitsu, T., et al. (2019) · Hypertension Research · doi:10.1038/s41440-019-0284-9 · Cited by 1,880
European Society of hypertension position paper on ambulatory blood pressure monitoring
O’Brien, E., Parati, G., Stergiou, G., Asmar, R., Beilin, L., Bilo, G., Clement, D., de la Sierra, A., de Leeuw, P., Dolan, E., et al. (2013) · Journal of Hypertension · doi:10.1097/hjh.0b013e328363e964 · Cited by 1,419
Self-citationAssessment and management of blood-pressure variability
Parati, G., Ochoa, J. E., Lombardi, C., & Bilo, G. (2013) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2013.1 · Cited by 853
Metadata
- Authors
- Verdecchia, P., Angeli, F., Mazzotta, G., Garofoli, M., Ramundo, E., Gentile, G., Ambrosio, G., & Reboldi, G.
- Venue
- Hypertension
- Published
- 2012-07
- Volume
- 60
- Issue
- 1
- Pages
- 34-42
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2148644774
- Cited by
- 284
- References
- 27
- FWCI
- 21.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Verdecchia, P., Angeli, F., Mazzotta, G., Garofoli, M., Ramundo, E., Gentile, G., Ambrosio, G., & Reboldi, G. (2012). Day-Night Dip and Early-Morning Surge in Blood Pressure in Hypertension: Prognostic Implications. Hypertension. https://doi.org/10.1161/hypertensionaha.112.191858
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
