Cited by 26Physical Activity and HealthCardiovascular Health and Risk FactorsCardiovascular Effects of Exercise

Associations of Leisure‐Time Physical Activity and Television Viewing With Life Expectancy Free of Nonfatal Cardiovascular Disease: The ARIC Study

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Cuthbertson, Carmen C., Tan, Xianming, Heiss, Gerardo, Kucharska‐Newton, Anna, Nichols, Hazel B., Kubota, Yasuhiko, Evenson, Kelly R.·2019·Journal of the American Heart Association

Abstract

Background: High levels of physical activity have been associated with longer life expectancy free of cardiovascular disease ( CVD ), but specific types of CVD and sedentary behavior have not been examined. We examined associations of leisure‐time moderate‐to‐vigorous physical activity ( LTPA ) and television viewing with life expectancy free of 3 types of CVD . Methods and Results: We included 13 534 participants from the ARIC (Atherosclerosis Risk in Communities) cohort. We used multistate survival models to estimate associations of LTPA in the past year (no LTPA , less than the median, equal to or greater than the median) and television viewing (often or very often, sometimes, seldom or rarely) with life expectancy at age 50 free of nonfatal coronary heart disease ( CHD ), stroke, and heart failure ( HF ). Over 27 years of follow‐up, 4519 participants developed one of the 3 nonfatal CVD s and 5475 deaths occurred. Compared with participants who engaged in no LTPA , participants who engaged in LTPA equal to or greater than the median had longer life expectancy free of nonfatal CHD (men: 1.5 years [95% CI , 1.0–2.0]; women: 1.6 years [95% CI , 1.1–2.2]), stroke (men: 1.8 years [95% CI , 1.2–2.3]; women: 1.8 years [95% CI , 1.3–2.3]), and HF (men: 1.6 years [95% CI , 1.1–2.1]; women: 1.7 years [95% CI , 1.2–2.2]). Compared with viewing more television, watching less television was associated with longer life expectancy free of CHD , stroke, and HF (≈0.8 year). Conclusions: Higher levels of LTPA and less television viewing were associated with longer life expectancy free of CHD, stroke, and HF. Engaging in LTPA and watching less television may increase the number of years lived free of CHD , stroke, and HF .

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  • Of the 28 studies in Table 2, 19 (68%) reported estimates indicating a protective effect of physical activity on risk of total stroke in women.

    “Of the 28 studies in Table 2, Nineteen studies (68%) reported estimates indicating a protective effect of physical activity on risk of stroke”

    From Sex Differences in Physical Activity and Incident Stroke: A Systematic Review (2022) · cites this paper as [36]

    The Results (Table 2; page unavailable) associate higher leisure-time physical activity with lower risk of nonfatal stroke in the ARIC cohort. But this is one cohort study, not a review of 28 studies; it does not report that 19 studies (68%) found a protective effect, nor does Table 2 give that count for women. (LLM, conf=0.86)

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  • Among those 17 papers, 6 (35%) suggested a significant effect of physical activity on total stroke in women but not in men.

    “6 (35%) of studies suggested a significant effect in women but not in men”

    From Sex Differences in Physical Activity and Incident Stroke: A Systematic Review (2022) · cites this paper as [36]

    The Results report an association between leisure-time physical activity and nonfatal stroke in the ARIC cohort, while the Methods describe sex as a covariate. Our copy does not report a review of 17 studies or a finding that 6 found a significant effect in women but not men (searched for the 6/17 figure and sex-specific stroke findings). (LLM, conf=0.76)

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Research works printed but not linked: 29

  1. [1]Mokdad AH, Ballestros K, Echko M, Glenn S, Olsen HE, Mullany E, Lee A, Khan AR, Ahmadi A, Ferrari AJ, Kasaeian A, Werdecker A, Carter A, Zipkin B, Sartorius B, Serdar B, Sykes BL, Troeger C, Fitzmaurice C, Rehm CD, Santomauro D, Kim D, Colombara D, Schwebel DC, Tsoi D, Kolte D, Nsoesie E, Nichols E, Oren E, Charlson FJ, Patton GC, Roth GA, Hosgood HD, Whiteford HA, Kyu H, Erskine HE, Huang H, Martopullo I, Singh JA, Nachega JB, Sanabria JR, Abbas K, Ong K, Tabb K, Krohn KJ, Cornaby L, Degenhardt L, Moses M, Farvid M, Griswold M, Criqui M, Bell M, Nguyen M, Wallin M, Mirarefin M, Qorbani M, Younis M, Fullman N, Liu P, Briant P, Gona P, Havmoller R, Leung R, Kimokoti R, Bazargan‐Hejazi S, Hay SI, Yadgir S, Biryukov S, Vollset SE, Alam T, Frank T, Farid T, Miller T, Vos T, Barnighausen T, Gebrehiwot TT, Yano Y, Al‐Aly Z, Mehari A, Handal A, Kandel A, Anderson B, Biroscak B, Mozaffarian D, Dorsey ER, Ding EL, Park EK, Wagner G, Hu G, Chen H, Sunshine JE, Khubchandani J, Leasher J, Leung J, Salomon J, Unutzer J, Cahill L, Cooper L, Horino M, Brauer M, Breitborde N, Hotez P, Topor‐Madry R, Soneji S, Stranges S, James S, Amrock S, Jayaraman S, Patel T, Akinyemiju T, Skirbekk V, Kinfu Y, Bhutta Z, Jonas JB, Murray CJL. The state of US health, 1990–2016: burden of diseases, injuries, and risk factors among US states. JAMA. 2018; 319: 1444– 1472. 29634829 PMC5933332
  2. [2]Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jimenez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O'Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P. Heart disease and stroke statistics—2018 update: a report from the American Heart Association. Circulation. 2018; 137: e67– e492. 29386200
  3. [5]Wahid A, Manek N, Nichols M, Kelly P, Foster C, Webster P, Kaur A, Friedemann Smith C, Wilkins E, Rayner M, Roberts N, Scarborough P. Quantifying the association between physical activity and cardiovascular disease and diabetes: a systematic review and meta‐analysis. J Am Heart Assoc. 2016; 5: e002495 DOI: 10.1161/JAHA.115.002495. 27628572 PMC5079002 · DOI · Paper page
  4. [7]Wen CP, Wai JP, Tsai MK, Yang YC, Cheng TY, Lee MC, Chan HT, Tsao CK, Tsai SP, Wu X. Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet. 2011; 378: 1244– 1253. 21846575
  5. [8]Franco OH, de Laet C, Peeters A, Jonker J, Mackenbach J, Nusselder W. Effects of physical activity on life expectancy with cardiovascular disease. Arch Intern Med. 2005; 165: 2355– 2360. 16287764
  6. [9]Nusselder WJ, Franco OH, Peeters A, Mackenbach JP. Living healthier for longer: comparative effects of three heart‐healthy behaviors on life expectancy with and without cardiovascular disease. BMC Public Health. 2009; 9: 487. 20034381 PMC2813239
  7. [10]O'Doherty MG, Cairns K, O'Neill V, Lamrock F, Jorgensen T, Brenner H, Schottker B, Wilsgaard T, Siganos G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee F. Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES). Eur J Epidemiol. 2016; 31: 455– 468. 26781655 PMC4901087
  8. [11]Pandey A, Salahuddin U, Garg S, Ayers C, Kulinski J, Anand V, Mayo H, Kumbhani DJ, de Lemos J, Berry JD. Continuous dose‐response association between sedentary time and risk for cardiovascular disease: a meta‐analysis. JAMA Cardiol. 2016; 1: 575– 583. 27434872
  9. [12]Chau JY, Grunseit AC, Chey T, Stamatakis E, Brown WJ, Matthews CE, Bauman AE, van der Ploeg HP. Daily sitting time and all‐cause mortality: a meta‐analysis. PLoS One. 2013; 8: e80000. 24236168 PMC3827429
  10. [13]Letter to the editor: standardized use of the terms “sedentary” and “sedentary behaviours”. Appl Physiol Nutr Metab. 2012; 37: 540– 542. 22540258
  11. [14]Matthews CE, Chen KY, Freedson PS, Buchowski MS, Beech BM, Pate RR, Troiano RP. Amount of time spent in sedentary behaviors in the United States, 2003–2004. Am J Epidemiol. 2008; 167: 875– 881. 18303006 PMC3527832
  12. [15]The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC Investigators. Am J Epidemiol. 1989; 129: 687– 702. 2646917
  13. [16]Baecke JA, Burema J, Frijters JE. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr. 1982; 36: 936– 942. 7137077
  14. [17]Folsom AR, Arnett DK, Hutchinson RG, Liao F, Clegg LX, Cooper LS. Physical activity and incidence of coronary heart disease in middle‐aged women and men. Med Sci Sports Exerc. 1997; 29: 901– 909. 9243489
  15. [18]Ainsworth BE, Haskell WL, Herrmann SD, Meckes N, Bassett DR Jr, Tudor‐Locke C, Greer JL, Vezina J, Whitt‐Glover MC, Leon AS. 2011 Compendium of Physical Activities: a second update of codes and MET values. Med Sci Sports Exerc. 2011; 43: 1575– 1581. 21681120
  16. [20]White AD, Folsom AR, Chambless LE, Sharret AR, Yang K, Conwill D, Higgins M, Williams OD, Tyroler HA. Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years’ experience. J Clin Epidemiol. 1996; 49: 223– 233. 8606324
  17. [22]Rosamond WD, Folsom AR, Chambless LE, Wang CH, McGovern PG, Howard G, Copper LS, Shahar E. Stroke incidence and survival among middle‐aged adults: 9‐year follow‐up of the Atherosclerosis Risk in Communities (ARIC) cohort. Stroke. 1999; 30: 736– 743. 10187871
  18. [23]Jones SA, Gottesman RF, Shahar E, Wruck L, Rosamond WD. Validity of hospital discharge diagnosis codes for stroke: the Atherosclerosis Risk in Communities Study. Stroke. 2014; 45: 3219– 3225. 25190443 PMC4290877
  19. [24]Atherosclerosis Risk in Communities Study. Manual 3A Surveillance of Heart Failure Manual of Operations Version 2.1. 2011 Available at: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/GetPdf.cgi?id=phd004516.1. Accessed July 24, 2019.
  20. [25]Rosamond WD, Chang PP, Baggett C, Johnson A, Bertoni AG, Shahar E, Deswal A, Heiss G, Chambless LE. Classification of heart failure in the Atherosclerosis Risk in Communities (ARIC) Study: a comparison of diagnostic criteria. Circ Heart Fail. 2012; 5: 152– 159. 22271752 PMC3326579
  21. [27]Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults—the evidence report. Obes Res. 1998; 6(suppl 2): 51S– 209S. 9813653
  22. [28]Jackson CH. Multi‐state models for panel data: the msm package for R. J Stat Softw. 2011; 38: 1– 28.
  23. [30]van den Hout A. ELECT: estimation of life expectancies using continuous‐time multi‐state survival models. 2014 Available at: http://www.ucl.ac.uk/~ucakadl/ELECT/ELECTManual_version0_1_2.pdf. Accessed February 20, 2017. 31416539
  24. [31]Azur MJ, Stuart EA, Frangakis C, Leaf PJ. Multiple imputation by chained equations: what is it and how does it work? Int J Methods Psychiatr Res. 2011; 20: 40– 49. 21499542 PMC3074241
  25. [32]White IR, Royston P, Wood AM. Multiple imputation using chained equations: issues and guidance for practice. Stat Med. 2011; 30: 377– 399. 21225900
  26. [33]Rubin DR. Multiple Imputation for Nonresponse in Surveys. New York: Wiley; 1987.
  27. [36]Sun JW, Zhao LG, Yang Y, Ma X, Wang YY, Xiang YB. Association between television viewing time and all‐cause mortality: a meta‐analysis of cohort studies. Am J Epidemiol. 2015; 182: 908– 916. 26568572
  28. [38]Richardson MT, Ainsworth BE, Wu HC, Jacobs DR Jr, Leon AS. Ability of the Atherosclerosis Risk in Communities (ARIC)/Baecke Questionnaire to assess leisure‐time physical activity. Int J Epidemiol. 1995; 24: 685– 693. 8550264
  29. [39]Jacobs DR Jr, Ainsworth BE, Hartman TJ, Leon AS. A simultaneous evaluation of 10 commonly used physical activity questionnaires. Med Sci Sports Exerc. 1993; 25: 81– 91. 8423759

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Authors
Cuthbertson, C. C., Tan, X., Heiss, G., Kucharska‐Newton, A., Nichols, H. B., Kubota, Y., & Evenson, K. R.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • Osaka Center for Cancer and Cardiovascular Disease Prevention (JP)
Corresponding author
Cuthbertson, Carmen C.
Venue
Journal of the American Heart Association
Published
2019-09-17
Volume
8
Issue
18
Pages
e012657-e012657
ISSN
2047-9980 (ISSN-L)
OpenAlex
W2971490256
Cited by
26
References
4
Citations by year
2026: 1 · 2025: 3 · 2024: 8 · 2023: 5 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 1
FWCI
1.54
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Journal of the American Heart Association (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • UNC Libraries
Funders
  • U.S. Department of Health and Human Services
  • National Institutes of Health
  • National Heart, Lung, and Blood Institute (T32HL007055)
  • National Institute of Environmental Health Sciences (P30ES010126)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords
leisure-time physical activity, television viewing, sedentary behavior, life expectancy, cardiovascular disease, coronary artery disease, stroke, heart failure, moderate-to-vigorous physical activity, sex differences
MeSH terms
Aged, Black or African American, Coronary Disease, Female, Heart Failure, Humans, Leisure Activities, Life Expectancy, Male, Middle Aged, Mortality, Television, United States, Exercise, Stroke, White People, Metabolic Equivalent

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