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Cited by 1,306Acute Ischemic Stroke ManagementCardiovascular Health and Risk FactorsHealth Promotion and Cardiovascular Prevention

The DOI matches its Crossref record; 719 of the 719 references it cites were found in a registry or an index.

Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Goldstein, Larry B., Bushnell, Cheryl D., Adams, Robert J., Appel, Lawrence J., Braun, Lynne T., Chaturvedi, Seemant, Creager, Mark A., Culebras, Antonio, Eckel, Robert H., Hart, Robert G., Hinchey, Judith A., Howard, Virginia J., Jauch, Edward C., Levine, Steven R., Meschia, James F., Moore, Wesley S., Nixon, J.V. (Ian), Pearson, Thomas A.·2011·Stroke
DOI 10.1161/str.0b013e3181fcb238
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Abstract

Background and Purpose—: This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke. Methods—: Writing group members were nominated by the committee chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association (AHA) Stroke Council Scientific Statement Oversight Committee and the AHA Manuscript Oversight Committee. The writing group used systematic literature reviews (covering the time since the last review was published in 2006 up to April 2009), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations using standard AHA criteria ( Tables 1 and 2 ). All members of the writing group had the opportunity to comment on the recommendations and approved the final version of this document. The guideline underwent extensive peer review by the Stroke Council leadership and the AHA scientific statements oversight committees before consideration and approval by the AHA Science Advisory and Coordinating Committee. Results—: Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race/ethnicity, and genetic predisposition. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat distribution. Less well-documented or potentially modifiable risk factors include the metabolic syndrome, excessive alcohol consumption, drug abuse, use of oral contraceptives, sleep-disordered breathing, migraine, hyperhomocysteinemia, elevated lipoprotein(a), hypercoagulability, inflammation, and infection. Data on the use of aspirin for primary stroke prevention are reviewed. Conclusion—: Extensive evidence identifies a variety of specific factors that increase the risk of a first stroke and that provide strategies for reducing that risk.

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Crossref · 10.1161/str.0b013e3181fcb238

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Research works printed but not linked: 7

  1. Tournier-Lasserve E, Joutel A, Chabriat H . Clinical phenotypes and genetic data in 15 unrelated families. Neurology. 1995;45(suppl 4):A273.
  2. 10.1542/peds.114.s2.555 · DOI
  3. Prevalence of diabetes and impaired fasting glucose in adults—United States 1999–2000. MMWR Morb Mortal Wkly Rep. 2003;52:833–837. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5235a1.htm. Published September 5 2003. Updated April 7 2004. Accessed August 14 2010.
  4. Guide to Clinical Preventive Services: Report of the U. S. Preventive Services Task Force. Baltimore MD: Williams and Wilkins; 1996. Available at: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=hscps2ed1996&part=A19920. Accessed October 14 2010.
  5. Hanson MR, Hodgeman JR, Conomy JP . A study of stroke associated with prolapsed mitral valve. Neurology. 1978;23:341.
  6. Adams R . In: , Embury S , ed. Sickle Cell Disease: Basic Principles and Clinical Practice. New York, NY: Raven Press;1994:599–621.
  7. Heart Disease and Stroke Statistics: 2009 Update. Dallas, TX: American Heart Association; 2009.

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Metadata

Authors
Goldstein, L. B., Bushnell, C. D., Adams, R. J., Appel, L. J., Braun, L. T., Chaturvedi, S., Creager, M. A., Culebras, A., Eckel, R. H., Hart, R. G., Hinchey, J. A., Howard, V. J., Jauch, E. C., Levine, S. R., Meschia, J. F., Moore, W. S., Nixon, J. V. (., & Pearson, T. A.
Affiliations
American Heart Association (US)
ORCID
Venue
Stroke
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2011-02
Volume
42
Issue
2
Pages
517-584
ISSN
  • 0039-2499 (ISSN-L)
  • 1524-4628
DOI
10.1161/str.0b013e3181fcb238
OpenAlex
W4211201192
Semantic Scholar
3d07af22ceda0b5c157f83800d855a75eb4ea554
Cited by
1,306
References
719
Citations by year
2026: 25 · 2025: 25 · 2024: 39 · 2023: 39 · 2022: 39 · 2021: 46 · 2020: 68 · 2019: 72 · 2018: 82 · 2017: 96 · 2016: 99 · 2015: 124 · 2014: 187 · 2013: 126 · 2012: 162
FWCI
85.19
Type
journal article
Language
en
Update notices
correction (2011-02-01)
Open access
closed
Locations
  • Stroke (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords
primary prevention, stroke risk factors, risk assessment, modifiable risk factors, hypertension, atrial fibrillation, dyslipidemia, carotid artery stenosis, diabetes mellitus, obesity, aspirin, hyperhomocysteinemia, metabolic syndrome, alcohol consumption, sleep-disordered breathing, migraine, hypercoagulability, inflammation, infection, hormone replacement therapy, sickle cell disease, cigarette smoking
MeSH terms
American Heart Association, Health Personnel, Humans, Primary Prevention, Risk Factors, United States, Evidence-Based Medicine, Stroke

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