The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Carotid Atherosclerosis Is a Stronger Predictor of Myocardial Infarction in Women Than in Men: A 6-Year Follow-Up Study of 6226 Persons: The Tromsø Study
Open accessAbstract
Background and Purpose— Ultrasound of carotid arteries provides measures of intima media thickness (IMT) and plaque, both widely used as surrogate measures of cardiovascular disease. Although IMT and plaques are highly intercorrelated, the relationship between carotid plaque and IMT and cardiovascular disease has been conflicting. In this prospective, population-based study, we measured carotid IMT, total plaque area, and plaque echogenicity as predictors for first-ever myocardial infarction (MI). Methods— IMT, total plaque area, and plaque echogenicity were measured in 6226 men and women aged 25 to 84 years with no previous MI. The subjects were followed for 6 years and incident MI was registered. Results— During follow-up, MI occurred in 6.6% of men and 3.0% of women. The adjusted relative risk (RR; 95% CI) between the highest plaque area tertile versus no plaque was 1.56 (1.04 to 2.36) in men and 3.95 (2.16 to 7.19) in women. In women, there was a significant trend toward a higher MI risk with more echolucent plaque. The adjusted RR (95% CI) in the highest versus lowest IMT quartile was 1.73 (0.98 to 3.06) in men and 2.86 (1.07 to 7.65) in women. When we excluded bulb IMT from analyses, IMT did not predict MI in either sex. Conclusions— In a general population, carotid plaque area was a stronger predictor of first-ever MI than was IMT. Carotid atherosclerosis was a stronger risk factor for MI in women than in men. In women, the risk of MI increased with plaque echolucency.
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Cited by
Carotid Intima-Media Thickness and Plaque in Cardiovascular Risk Assessment
Naqvi, T. Z., & Lee, M.-S. (2014) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2013.11.014 · Cited by 649
Spence, J. D. (2010) · Archives of Neurology · doi:10.1001/archneurol.2009.289 · Cited by 342
Mathiesen, E. B., Johnsen, S. H., Wilsgaard, T., Bønaa, K. H., Løchen, M.-L., & Njølstad, I. (2011) · Stroke · doi:10.1161/strokeaha.110.589754 · Cited by 324
Self-citationThe Value of Carotid Intima-Media Thickness for Predicting Cardiovascular Risk
Simon, A., Megnien, J.-L., & Chironi, G. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.109.196980 · Cited by 286
the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics · doi:10.1038/ng.920 · Cited by 212
Metadata
- Authors
- Johnsen, S. H., Mathiesen, E. B., Joakimsen, O., Stensland, E., Wilsgaard, T., Løchen, M.-L., Njølstad, I., & Arnesen, E.
- Venue
- Stroke
- Published
- 2007-11
- Volume
- 38
- Issue
- 11
- Pages
- 2873-2880
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2116802774
- Cited by
- 398
- References
- 38
- FWCI
- 12.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Johnsen, S. H., Mathiesen, E. B., Joakimsen, O., Stensland, E., Wilsgaard, T., Løchen, M.-L., Njølstad, I., & Arnesen, E. (2007). Carotid Atherosclerosis Is a Stronger Predictor of Myocardial Infarction in Women Than in Men: A 6-Year Follow-Up Study of 6226 Persons: The Tromsø Study. Stroke. https://doi.org/10.1161/strokeaha.107.487264
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