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Cited by 572

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

The Importance of Size: Successful Recanalization by Intravenous Thrombolysis in Acute Anterior Stroke Depends on Thrombus Length

Open access
Riedel, Christian H., Zimmermann, Philip, Jensen-Kondering, Ulf, Stingele, Robert, Deuschl, Günther, Jansen, Olav·2011·Stroke

Abstract

Background and Purpose—: We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. Methods—: In 138 patients who presented with acute middle cerebral artery stroke and who were treated with intravenous thrombolysis (IVT), we measured lengths of thrombotic clots depicted as arterial hyperdensities in admission nonenhanced CT images with 2.5-mm slice width. Vascular recanalization was investigated after thrombolysis and recanalization results were related to thrombus lengths by logistic regression. Results—: In 62 patients, IVT resulted in recanalization; among these patients, no thrombus length exceeded 8 mm. The median modified Rankin scale score at hospital discharge was 2. In the remaining 76 patients, thrombus lengths mostly exceeded 8 mm and IVT failed in recanalization. These patients were discharged with a median modified Rankin scale score of 5. Conclusions—: This study shows that in acute middle cerebral artery stroke, IVT has nearly no potential to recanalize occluded vessels if thrombus length exceeds 8 mm.

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Crossref · 10.1161/strokeaha.110.609693

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Metadata

Authors
Riedel, C. H., Zimmermann, P., Jensen-Kondering, U., Stingele, R., Deuschl, G., & Jansen, O.
Venue
Stroke
Published
2011-06
Volume
42
Issue
6
Pages
1775-1777
ISSN
  • 0039-2499 (ISSN-L)
  • 1524-4628
OpenAlex
W2103780795
Cited by
572
References
7
FWCI
33.93
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Importance of Size: Successful Recanalization by Intravenous Thrombolysis in Acute Anterior Stroke Depends on Thrombus Length. https://app.cochat.ai/papers/10.1161/strokeaha.110.609693
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Riedel, C. H., Zimmermann, P., Jensen-Kondering, U., Stingele, R., Deuschl, G., & Jansen, O. (2011). The Importance of Size: Successful Recanalization by Intravenous Thrombolysis in Acute Anterior Stroke Depends on Thrombus Length. Stroke. https://doi.org/10.1161/strokeaha.110.609693

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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