Preanalytical considerations in blood gas analysis
Open accessAbstract
Blood gas testing is a commonly ordered test in hospital settings, where the results almost always have the potential to dictate an immediate or urgent response. The preanalytical steps in testing, from choosing the correct tests to ensuring the specimen is introduced into the instrument correctly, must be perfectly coordinated to ensure that the patient receives appropriate and timely therapy in response to the analytical results. While many of the preanalytical steps in blood gas testing are common to all laboratory tests, such as accurate specimen labeling, some are unique to this testing because of the physicochemical properties of the analytes being measured. The common sources of preanalytical variation in blood gas testing are reviewed here.
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POCT is commonly performed in healthcare settings located outside of direct jurisdiction and control of the laboratory.
“Thus, considering that POCT is commonly performed in healthcare settings located outside of direct jurisdiction and control of the laboratory, reinforced education on all potential preanalytical errors must be delivered to all healthcare professionals who have direct responsibility for performing POCT [64].”
From Point-of-care testing: state-of-the art and perspectives (2025) · cites this paper as [64]
The POC Considerations section says point-of-care blood gas testing is common in operating rooms, emergency rooms, and the field, supporting the claim that it often occurs outside the laboratory. It does not establish that those settings are outside the laboratory’s direct jurisdiction or control; physical location alone does not settle that qualifier. The sentence’s call for reinforced education is the citing authors’ conclusion, not the point assessed here. (LLM, conf=0.82)
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- Authors
- Baird, G.
- Affiliations
- University of Washington (US)
- Corresponding author
- Baird, Geoffrey
- ORCID
- Baird, Geoffrey
- Venue
- Biochemia Medica
- Published
- 2013
- Volume
- 23
- Issue
- 1
- Pages
- 19-27
- ISSN
- 1330-0962 (ISSN-L)
- 1846-7482
- PMC
- PMC3900096
- OpenAlex
- W2052096223
- Cited by
- 90
- References
- 59
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 13 · 2023: 10 · 2022: 12 · 2021: 8 · 2020: 3 · 2019: 10 · 2018: 10 · 2017: 4 · 2016: 4 · 2015: 4 · 2014: 1 · 2013: 1
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Biochemia Medica (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Hrčak Portal of scientific journals of Croatia (University Computing Centre) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
- Health Sciences › Medicine › Nephrology › Renal function and acid-base balance
- Keywords
- blood gas analysis, pre-analytical variables, pre-analytical variability, sample handling, specimen labels, point-of-care testing, clinical laboratory testing
- MeSH terms
- Blood Gas Analysis, Diagnostic Errors, Humans, Specimen Handling, Clinical Laboratory Techniques
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