The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Effects of nasal CPAP on sympathetic activity in patients with heart failure and central sleep apnea.
Abstract
We hypothesized that (1) patients with congestive heart failure (CHF) and Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) would have greater nocturnal urinary and daytime plasma norepinephrine concentrations (UNE and PNE, respectively) than those without CSR-CSA because of apneas, hypoxia and arousals from sleep and (2) attenuation of CSR-CSA by nasal continuous positive airway pressure (NCPAP) would reduce UNE and PNE concentrations. Eighteen patients with and 17 without CSR-CSA (Non-CSR-CSA group) were studied. Left ventricular ejection fraction was similar in the two groups, but overnight UNE and awake PNE concentrations were greater in the CSR-CSA group (30.2 +/- 2.5 nmol/mmol creatinine and 3.32 +/- 0.29 nmol/L) than in the Non-CSR-CSA group (15.8 +/- 2.1 nmol/mmol creatinine, p < 0.005, and 2.06 +/- 0.56 nmol/L, p < 0.05, respectively). Patients with CSR-CSA were randomized to a control group or to nightly NCPAP for 1 mo. CSR-CSA was attenuated in the NCPAP but not in the control group. The NCPAP group experienced greater reductions in UNE and PNE concentrations (-12.5 +/- 3.3 nmol/mmol creatinine and -0.74 +/- 0.40 nmol/L) than did the control group (-1.3 +/- 2.8 nmol/mmol creatinine, p < 0.025 and 1.16 +/- 0.66 nmol/L, p < 0.025, respectively). In conclusion, in patients with CHF, CSR-CSA is associated with elevated sympathoneural activity, which can be reduced by NCPAP.
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Citations
Cites
Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure
Cohn, J. N., Levine, T. B., Olivari, M. T., Garberg, V., Lura, D., Francis, G. S., Simon, A. B., & Rector, T. (1984) · New England Journal of Medicine · doi:10.1056/nejm198409273111303 · Cited by 3,125
Cohn, J. N., Johnson, G., Ziesche, S., Cobb, F., Francis, G., Tristani, F., Smith, R., Dunkman, W. B., Loeb, H., Wong, M., et al. (1991) · New England Journal of Medicine · doi:10.1056/nejm199108013250502 · Cited by 2,833
Hasking, G. J., Esler, M. D., Jennings, G. L., Burton, D., Johns, J. A., & Korner, P. I. (1986) · Circulation · doi:10.1161/01.cir.73.4.615 · Cited by 1,028
Naughton, M., Benard, D., Tam, A., Rutherford, R., & Bradley, T. D. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/148.2.330 · Cited by 393
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Cited by
Goldberger, J. J., Cain, M. E., Hohnloser, S. H., Kadish, A. H., Knight, B. P., Lauer, M. S., Maron, B. J., Page, R. L., Passman, R. S., Siscovick, D., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.189375 · Cited by 1,450
Javaheri, S., Barbe, F., Campos-Rodriguez, F., Dempsey, J. A., Khayat, R., Javaheri, S., Malhotra, A., Martinez-Garcia, M. A., Mehra, R., Pack, A. I., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.11.069 · Cited by 1,434
Continuous Positive Airway Pressure for Central Sleep Apnea and Heart Failure
Bradley, T. D., Logan, A. G., Kimoff, R. J., Sériès, F., Morrison, D., Ferguson, K., Belenkie, I., Pfeifer, M., Fleetham, J., Hanly, P., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa051001 · Cited by 1,189
Self-citationJavaheri, S., Parker, T. J., Liming, J. D., Corbett, W. S., Nishiyama, H., Wexler, L., & Roselle, G. A. (1998) · Circulation · doi:10.1161/01.cir.97.21.2154 · Cited by 1,160
Kaneko, Y., Floras, J. S., Usui, K., Plante, J., Tkacova, R., Kubo, T., Ando, S.-I., & Bradley, T. D. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022479 · Cited by 1,051
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Metadata
- Authors
- Naughton, M. T., Benard, D. C., Liu, P. P., Rutherford, R., Rankin, F., & Bradley, T. D.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-08
- Volume
- 152
- Issue
- 2
- Pages
- 473-479
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2080325887
- Cited by
- 475
- References
- 4
- FWCI
- 5.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- Naughton, M. T., Benard, D. C., Liu, P. P., Rutherford, R., Rankin, F., & Bradley, T. D. (1995). Effects of nasal CPAP on sympathetic activity in patients with heart failure and central sleep apnea. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.152.2.7633695
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
