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Cited by 428

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Alternaria as a major allergen for asthma in children raised in a desert environment.

Halonen, M, Stern, D A, Wright, A L, Taussig, L M, Martinez, F D·1997·American Journal of Respiratory and Critical Care Medicine

Abstract

The relationships of asthma and allergic rhinitis with individual immediate skin test responses were examined for preferential associations and for changes with age in children raised in a semiarid environment. Prevalence of physician-diagnosed asthma was 9.8% at age 6 (n = 948) and 15.5% at age 11 (n = 895). Immediate skin test responses to Bermuda grass were the most prevalent among children with allergic rhinitis and control subjects, whereas responses to the mold, Altenaria alternata, were the most prevalent among asthmatics. Skin test responses for crude house dust, Dermatophagoides farinae, and cat had low prevalences in all groups. By logistic regression, Alternaria was the only allergen independently associated with increased risk for asthma at both ages 6 and 11. Allergic rhinitis showed independent association with sensitization to Bermuda grass and mulberry tree pollen at age 11 but did not show an independent relation to any single allergen at age 6. Logistic regression further revealed that persistent asthma (diagnosed before age 6) was independently associated with Alternaria skin tests at both ages 6 and 11, whereas new asthma (diagnosed after age 6) was associated with Alternaria skin tests at age 6 but not at age 11. We conclude that Alternaria is the major allergen associated with the development of asthma in children raised in a semiarid environment and that skin test responses at age 6 are more closely linked to asthma than those at age 11.

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Crossref · 10.1164/ajrccm.155.4.9105079

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Metadata

Authors
Halonen, M., Stern, D. A., Wright, A. L., Taussig, L. M., & Martinez, F. D.
Venue
American Journal of Respiratory and Critical Care Medicine
Published
1997-04
Volume
155
Issue
4
Pages
1356-1361
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
OpenAlex
W2101520378
Cited by
428
References
19
FWCI
11.48
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Alternaria as a major allergen for asthma in children raised in a desert environment. https://app.cochat.ai/papers/10.1164/ajrccm.155.4.9105079
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Halonen, M., Stern, D. A., Wright, A. L., Taussig, L. M., & Martinez, F. D. (1997). Alternaria as a major allergen for asthma in children raised in a desert environment. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.155.4.9105079

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