The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Alternaria as a major allergen for asthma in children raised in a desert environment.
Abstract
The relationships of asthma and allergic rhinitis with individual immediate skin test responses were examined for preferential associations and for changes with age in children raised in a semiarid environment. Prevalence of physician-diagnosed asthma was 9.8% at age 6 (n = 948) and 15.5% at age 11 (n = 895). Immediate skin test responses to Bermuda grass were the most prevalent among children with allergic rhinitis and control subjects, whereas responses to the mold, Altenaria alternata, were the most prevalent among asthmatics. Skin test responses for crude house dust, Dermatophagoides farinae, and cat had low prevalences in all groups. By logistic regression, Alternaria was the only allergen independently associated with increased risk for asthma at both ages 6 and 11. Allergic rhinitis showed independent association with sensitization to Bermuda grass and mulberry tree pollen at age 11 but did not show an independent relation to any single allergen at age 6. Logistic regression further revealed that persistent asthma (diagnosed before age 6) was independently associated with Alternaria skin tests at both ages 6 and 11, whereas new asthma (diagnosed after age 6) was associated with Alternaria skin tests at age 6 but not at age 11. We conclude that Alternaria is the major allergen associated with the development of asthma in children raised in a semiarid environment and that skin test responses at age 6 are more closely linked to asthma than those at age 11.
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Cites
Asthma and Wheezing in the First Six Years of Life
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Self-citationAssociation of Asthma with Serum IgE Levels and Skin-Test Reactivity to Allergens
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A Community-based Study of the Epidemiology of Asthma: Incidence Rates, 1964–1983
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Dust mite allergens and asthma—A worldwide problem
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THE TUCSON CHILDREN'S RESPIRATORY STUDY
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Cited by
GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION
PAUWELS, R. A. (1996) · Arerugī/Arerugi · doi:10.15036/arerugi.45.792 · Cited by 9,994
Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years
Stein, R. T., Sherrill, D., Morgan, W. J., Holberg, C. J., Halonen, M., Taussig, L. M., Wright, A. L., & Martinez, F. D. (1999) · The Lancet · doi:10.1016/s0140-6736(98)10321-5 · Cited by 1,633
Self-citationBioaerosol Health Effects and Exposure Assessment: Progress and Prospects
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A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing
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Self-citation(2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.162.6.ats9-00 · Cited by 909
Metadata
- Authors
- Halonen, M., Stern, D. A., Wright, A. L., Taussig, L. M., & Martinez, F. D.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1997-04
- Volume
- 155
- Issue
- 4
- Pages
- 1356-1361
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2101520378
- Cited by
- 428
- References
- 19
- FWCI
- 11.48
- Type
- journal article
- Language
- en
- Open access
- closed
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- Halonen, M., Stern, D. A., Wright, A. L., Taussig, L. M., & Martinez, F. D. (1997). Alternaria as a major allergen for asthma in children raised in a desert environment. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.155.4.9105079
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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