Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 1,153

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing

CASTRO-RODRÍGUEZ, JOSÉ A., HOLBERG, CATHARINE J., WRIGHT, ANNE L., MARTINEZ, FERNANDO D.·2000·American Journal of Respiratory and Critical Care Medicine

Abstract

Because most cases of asthma begin during the first years of life, identification of young children at high risk of developing the disease is an important public health priority. We used data from the Tucson Children's Respiratory Study to develop two indices for the prediction of asthma. A stringent index included frequent wheezing during the first 3 yr of life and either one major risk factor (parental history of asthma or eczema) or two of three minor risk factors (eosinophilia, wheezing without colds, and allergic rhinitis). A loose index required any wheezing during the first 3 yr of life plus the same combination of risk factors described previously. Children with a positive loose index were 2.6 to 5.5 times more likely to have active asthma between ages 6 and 13 than children with a negative loose index. Risk of having subsequent asthma increased to 4.3 to 9.8 times when a stringent index was used. We found that 59% of children with a positive loose index and 76% of those with a positive stringent index had active asthma in at least one survey during the school years. Over 95% of children with a negative stringent index never had active asthma between ages 6 and 13. We conclude that the subsequent development of asthma can be predicted with reasonable accuracy using simple, clinically based parameters.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1164/ajrccm.162.4.9912111

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 7 references

Cited by

See all 1,153

Metadata

Authors
CASTRO-RODRÍGUEZ, J. A., HOLBERG, C. J., WRIGHT, A. L., & MARTINEZ, F. D.
Venue
American Journal of Respiratory and Critical Care Medicine
Published
2000-10-01
Volume
162
Issue
4
Pages
1403-1406
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
OpenAlex
W2134902690
Cited by
1,153
References
7
FWCI
10.96
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing. https://app.cochat.ai/papers/10.1164/ajrccm.162.4.9912111
The paper
CASTRO-RODRÍGUEZ, J. A., HOLBERG, C. J., WRIGHT, A. L., & MARTINEZ, F. D. (2000). A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.162.4.9912111

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.