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Comparison of Discriminative Properties among Disease-specific Questionnaires for Measuring Health-related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease
Abstract
Three disease-specific, health-related quality of life (HRQL) questionnaires have been introduced to assess patients with chronic obstructive pulmonary disease (COPD): the St. George's Respiratory Questionnaire (SGRQ), the Breathing Problems Questionnaire (BPQ), and the Chronic Respiratory Disease Questionnaire (CRQ). The purpose of the present study was to make comparisons between the SGRQ, the BPQ, and the CRQ in their discriminative properties, and to clarify the characteristics of each questionnaire. One hundred forty-three patients with mild to severe COPD completed pulmonary function tests, progressive cycle ergometer testing for exercise capacity, assessment of dyspnea, anxiety, and depression, and assessment of HRQL. The frequency distributions of the questionnaire scores showed that the SGRQ and the CRQ were normally distributed and that the BPQ was skewed toward low scores. Relationships between all dimensions of the three questionnaires were significant (correlation coefficients [Rs] = 0.74 to 0.86). The three questionnaires had significant but weak correlations (Rs = -0.24 to -0.36) with some physiologic variables (VC, FEV1, and DL(CO)/VA) and mild to moderate correlations with exercise capacity and assessment of dyspnea, anxiety, and depression. Stepwise multiple regression analyses revealed that the Baseline Dyspnea Index (BDI) score, anxiety by the Hospital Anxiety Depression Scale (HAD), and maximal oxygen uptake (VO2max) accounted for 61% of the variance in the SGRQ and that the BDI and anxiety of the HAD accounted for 53 and 49% of the variance in the BPQ and the CRQ, respectively. Dyspnea and psychologic status impacted the HRQL in patients with COPD. Although no substantial differences between the SGRQ, the BPQ, and the CRQ were evident in the correlations with physiologic parameters and the influential factors, the BPQ was found to be less discriminatory than the SGRQ and the CRQ in evaluating HRQL cross-sectionally.
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“The diagnosis of COPD is often made only after patients present with symptoms that have demanded a change in lifestyle and a reduction in quality of life.75”
From Anxiety and Depression in COPD (2008) · cites this paper as [75]
Citations
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Coefficient Alpha and the Internal Structure of Tests
Cronbach, L. J. (1951) · Psychometrika · doi:10.1007/bf02310555 · Cited by 43,931
Jones, P. W., Quirk, F. H., Baveystock, C. M., & Littlejohns, P. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/145.6.1321 · Cited by 3,035
Assessment of Quality-of-Life Outcomes
Testa, M. A., & Simonson, D. C. (1996) · New England Journal of Medicine · doi:10.1056/nejm199603283341306 · Cited by 2,606
A measure of quality of life for clinical trials in chronic lung disease
Guyatt, G. H., Berman, L. B., Townsend, M., Pugsley, S. O., & Chambers, L. W. (1987) · Thorax · doi:10.1136/thx.42.10.773 · Cited by 1,721
Mahler, D. A., Weinberg, D. H., Wells, C. K., & Feinstein, A. R. (1984) · CHEST Journal · doi:10.1378/chest.85.6.751 · Cited by 1,289
Life quality of patients with chronic obstructive pulmonary disease
McSweeny, A. J. (1982) · Archives of Internal Medicine · doi:10.1001/archinte.1982.00340160057014 · Cited by 490
Ferrer, M., Alonso, J., Prieto, L. M., Plaza, V., Monsó, E., Marrades, R. M., Aguar, M. C., Khalaf, A., & Anto, J. M. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09061160 · Cited by 432
Wijkstra, P., van Altena, R., Kraan, J., Otten, V., Postma, D. S., & Koëter, G. H. (1994) · European Respiratory Journal · doi:10.1183/09031936.94.07020269 · Cited by 328
Prigatano, G. P. (1984) · Archives of Internal Medicine · doi:10.1001/archinte.1984.00350200121018 · Cited by 300
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Research works printed but not linked: 1
- Medical Section of the American Lung Association, 1994, Standardization of spirometry: 1994 update., Am. Rev. Respir. Dis., 152, 1107
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Yi, X. L., & Liu, S. (2021) · Environmental Research · doi:10.1016/j.envres.2021.110768 · Cited by 7
Pamela Serón, S., Pablo Riedemann, G., Sanhueza, A., Doussoulin, A., & Paola Villarroel, A. (2003) · Revista médica de Chile · doi:10.4067/s0034-98872003001100003 · Cited by 7
Rivadeneira, M. F. (2015) · Revista CUIDARTE · doi:10.15649/cuidarte.v6i1.109 · Cited by 6
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Ayora, A. F., Soler, L. M., & Cervera‐Gasch, Á. (2019) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 6
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Maoua, M., Maâlel, O. E., Abdelghani, A., Boughattas, W., Kalboussi, H., Chatti, S., Ibrahim, H. B. H., Brahem, A., Debbabi, F., Benzarti, M., et al. (2014) · Revue de Pneumologie Clinique · doi:10.1016/j.pneumo.2013.11.009 · Cited by 6
Miki, K., Kitada, S., Miki, M., Hui, S., Shrestha, R., Yoshimura, K., Tsujino, K., Kagawa, H., Oshitani, Y., Kida, H., et al. (2019) · The Journal of Physiological Sciences · doi:10.1007/s12576-019-00716-2 · Cited by 6
Sokai, A., Handa, T., Oga, T., Tanizawa, K., Ikezoe, K., Nakatsuka, Y., Kubo, T., Kumiko, K., Chin, K., & Mishima, M. (2017) · Sarcoidosis vasculitis and diffuse lung diseases · doi:10.36141/svdld.v34i3.5214 · Cited by 6
Gigliotti, F., Grazzini, M., Stendardi, L., Romagnoli, P., & Scano, G. (2002) · Respiratory Medicine · doi:10.1053/rmed.2001.1275 · Cited by 6
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Rodríguez, A. G., Picabia, I. B., & Gregorio, Á. P. S. (2002) · European Psychologist · doi:10.1027//1016-9040.7.2.125 · Cited by 6
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Chavannes, N. H., & van Schayck, O. C. P. (2000) · BioDrugs · doi:10.2165/00063030-200013020-00006 · Cited by 6
Nishimura, K., Kusunose, M., Shibayama, A., & Nakayasu, K. (2025) · Journal of Patient-Reported Outcomes · doi:10.1186/s41687-025-00923-z · Cited by 5
Kristan, S. Š. (2013) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-013-0237-y · Cited by 5
Guan, L., Xu, J., Wu, W., Chen, J., Li, X., Guo, B., Yang, Y., Huo, Y., Zhou, L., & Chen, R. (2018) · International Journal of COPD · doi:10.2147/copd.s156135 · Cited by 5
Ayora, A. F., Soler, L. M., & Gasch, A. C. (2019) · Revista Latino-Americana de Enfermagem · doi:10.1590/1518-8345.2624.3148 · Cited by 5
Khalladi, R., Gargouri, I., Mahjoub, M., Belhareth, S., & Saad, H. B. (2017) · Revue de Pneumologie Clinique · doi:10.1016/j.pneumo.2017.08.004 · Cited by 5
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Clini, E. M., Crisafulli, E., Roca, M., & Malerba, M. (2013) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2012.12.009 · Cited by 5
Takeuchi, T., Nakao, M., Shinozaki, Y., & Yano, E. (2010) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2010.505342 · Cited by 4
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Lee, E. J., & Euna, P. A. R. K. (2016) · Journal of the Korea Academia-Industrial cooperation Society · doi:10.5762/kais.2016.17.5.260 · Cited by 4
Tanabe, N., Muro, S., Fuseya, Y., Satô, S., Oguma, T., Kiyokawa, H., Takahashi, T., Kinose, D., Hoshino, Y., Kubo, T., et al. (2012) · Respirology · doi:10.1111/j.1440-1843.2012.02221.x · Cited by 4
Tillie‐Leblond, I., & Masure, F. (2006) · Revue des Maladies Respiratoires · doi:10.1016/s0761-8425(06)71607-2 · Cited by 4
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Knaz, H., Anane, I., Guezguez, F., Prefaut, C., & Saad, H. B. (2020) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2020.07.005 · Cited by 3
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Fixed combination therapies in COPD--effect on quality of life.
Groneberg‐Kloft, B., Fischer, A., & Welte, T. (2007) · Europe PMC (PubMed Central) · Cited by 3
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Geijer, R. M. M. (2006) · Utrecht University Repository (Utrecht University) · Cited by 3
Efremidis, G., Manolis, A. S., & Spiropoulos, K. V. (2005) · Clinical Pulmonary Medicine · doi:10.1097/01.cpm.0000187186.51065.3b · Cited by 3
Otake, S., Chubachi, S., Nakayama, S., Sakurai, K., Irie, H., Hashiguchi, M. H., Itabashi, Y., Yamada, Y., Jinzaki, M., Murata, M., et al. (2021) · Respiration · doi:10.1159/000519668 · Cited by 2
López-Vargas, R., Flores, M. E. D., Sandoval, R., & López-Muro, M. (2005) · Revista del Instituto Nacional de Enfermedades Respiratorias · Cited by 2
Ushiki, A., Fujimoto, K., Ito, M., Yasuo, M., Urushihata, K., Hanaoka, M., & Kubo, K. (2013) · SOAR (Shinshu University) · Cited by 2
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Horie, J., Takahashi, K., Shiranita, S., Anami, K., & Hayashi, S. (2021) · Healthcare · doi:10.3390/healthcare9010053 · Cited by 2
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Karwa, M. L., Chandra, A., & Mirza, A. (2007) · Springer eBooks · doi:10.1007/978-0-387-70875-1_7 · Cited by 2
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Jones, P. W. (2007) · doi:10.1002/9780470755976.ch16 · Cited by 2
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Astute, Assertive, and Alpha-1: Quantifying Empowerment in a Rare Genetic Community.
Finn, S. (2008) · ProQuest LLC eBooks · Cited by 1
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Celli, B. R. (2007) · doi:10.1002/9780470755976.ch15 · Cited by 1
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Geijer, R. M. M., Sachs, A. P. E., Verheij, T. J., Kerstjens, H. A. M., Kuyvenhoven, M. M., & Hoes, A. W. (2009) · Huisarts en Wetenschap · doi:10.1007/bf03085495 · Cited by 1
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Thom, D. H., Su, G., Hessler, D., & Willard‐Grace, R. (2019) · doi:10.25302/9.2019.ad.130603900 · Cited by 1
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Menon, P. R., & Stapleton, R. D. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-727-3_14
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Antoniu, S. A., Mihăescu, T., Carone, M., & Donner, C. F. (2003) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1586/14737167.3.1.57
Mena, A. M., & José, P. (2006) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
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Kamei, T. (2014) · Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics · doi:10.3143/geriatrics.51.42
Mishima, M. (2012) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.101.1529
Future expectations in COPD: measures of success
Calverley, P. M. A. (2004)
An Integrated Approach to the Pharmacological Therapy of COPD
Celli, B. R. (2003) · Lung biology in health and disease · doi:10.1201/9780203913406.ch17
Khalladi, R., & Saad, H. B. (2017) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2016.10.377
Ferrari, R., Lucheta, P. A., Faganello, M. M., & Godoy, I. (2010)
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Казолла, М., Мак-Ни, В., Мартинес, Ф. Д., Rabe, K. F., Франчиози, Л. Д., Барнс, П. Д., Брусаско, В., Бурдж, П. С., Калверлей, П. М., Селли, Б. Р., et al. (2010) · PULMONOLOGIYA · doi:10.18093/0869-0189-2010-1-13-65
Study on COPD from Digital Imaging to iPS Sell Study
Mishima, M. (2015) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.104.65a
Study on COPD from Digital Imaging to iPS Sell Study
Mishima, M. (2015) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.104.1725
Murata, T., Morimoto, K., Matsuyama, F., Yamada, M., Feliciano, J., & Hassan, M. (2023) · Journal of Medical Economics · doi:10.1080/13696998.2023.2189858
Oi, I., Ito, I., Hamao, N., Shirata, M., Nishioka, K., Hayashi, Y., Imai, S., & Hirai, T. (2026) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2026.102992
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Gupta, E., & Stapleton, R. D. (2026) · Respiratory medicine · doi:10.1007/978-3-032-29861-4_17
Nishimura, K., Kusunose, M., Shibayama, A., & Nakayasu, K. (2026) · Patient Related Outcome Measures · doi:10.1080/1179271x.2026.2732832
Williams, R. (2013) · UKnowledge (University of Kentucky)
Breyer, M. (2013)
Metadata
- Authors
- HAJIRO, T., NISHIMURA, K., TSUKINO, M., IKEDA, A., KOYAMA, H., & IZUMI, T.
- Affiliations
- Kyoto University (JP)
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-03-01
- Volume
- 157
- Issue
- 3
- Pages
- 785-790
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2071805440
- Cited by
- 265
- References
- 21
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 8 · 2021: 8 · 2020: 7 · 2019: 6 · 2018: 6 · 2017: 11 · 2016: 8 · 2015: 8 · 2014: 13 · 2013: 14 · 2012: 14
- FWCI
- 7.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Keywords
- chronic obstructive pulmonary disease, health-related quality of life, disease-specific questionnaire, St George's Respiratory Questionnaire, Chronic Respiratory Questionnaire, dyspnea, anxiety, depression, exercise capacity, VO2max, lung function
- MeSH terms
- Aged, Aged, 80 and over, Anxiety, Cross-Sectional Studies, Depression, Dyspnea, Evaluation Studies as Topic, Exercise Test, Forced Expiratory Volume, Health Status, Humans, Lung Diseases, Obstructive, Middle Aged, Oxygen Consumption, Pulmonary Diffusing Capacity, Quality of Life, Surveys and Questionnaires, Regression Analysis, Respiration, Respiratory Function Tests, Vital Capacity, Discriminant Analysis, Exercise Tolerance
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