Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

Barnes, P. J., & Karin, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704103361506 · Cited by 4,622

Transforming Growth Factor β in Tissue Fibrosis

Epstein, F. H., Border, W. A., & Noble, N. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199411103311907 · Cited by 3,044

Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Robinson, D. S., Hamid, Q. A., Ying, S., Tsicopoulos, A., Barkans, J. R., Bentley, A. M., Corrigan, C. J., Durham, S. R., & Kay, A. B. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201303260504 · Cited by 2,769

Eosinophilic Inflammation in Asthma

Bousquet, J., Chanez, P., Lacoste, J. Y., Barneon, G., Ghavanian, N., Enander, I., Venge, P., Ahlstedt, S., Simony-Lafontaine, J., Godard, P., et al. (1990) · New England Journal of Medicine · doi:10.1056/nejm199010113231505 · Cited by 2,499

Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma

PAUWELS, R. A., Löfdahl, C., Postma, D. S., Tattersfield, A. E., O’Byrne, P. M., Barnes, P. J., & Ullman, A. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711133372001 · Cited by 1,518

Increased nitric oxide in exhaled air of asthmatic patients

Kharitonov, S. A., Yates, D. H., Robbins, R. A., Barnes, P. J., Logan-Sinclair, R., & Shinebourne, E. A. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90931-8 · Cited by 1,432

The matrix‐degrading metalloproteinases

Matrisian, L. M. (1992) · BioEssays · doi:10.1002/bies.950140705 · Cited by 1,362

Life, death, and the pursuit of apoptosis.Preprint

White, E. (1996) · Genes & Development · doi:10.1101/gad.10.1.1 · Cited by 1,306

Collagen family of proteins

REST, M. V. D., & Garrone, R. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.13.1916105 · Cited by 1,302

Damage of the Airway Epithelium and Bronchial Reactivity in Patients with Asthma

Laitinen, L. A., Heino, M., Laitinen, A., Kava, T., & Haahtela, T. (1985) · American Review of Respiratory Disease · doi:10.1164/arrd.1985.131.4.599 · Cited by 1,278

Corticosteroid enhances TNF‐α‐mediated leukocyte adhesion to pulmonary microvascular endothelial cells

Matsuda, A., Orihara, K., Fukuda, S., Fujinaga, H., Matsumoto, K., & Saito, H. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01775.x · Cited by 31

Osteopontin and allergic disease: pathophysiology and implications for diagnostics and therapy

Frenzel, D. F., & Weiss, J. M. (2010) · Expert Review of Clinical Immunology · doi:10.1586/eci.10.82 · Cited by 31

Evaluation of subcutaneous versus mucosal (intranasal) allergen-specific rush immunotherapy in experimental feline asthma

Lee‐Fowler, T. M., Cohn, L. A., DeClue, A. E., Spinka, C., & Reinero, C. R. (2008) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2008.12.008 · Cited by 31

Mechanical strain enhances proteoglycan message in fibroblasts from asthmatic subjects

Ludwig, M. S., Ftouhi‐Paquin, N., Huang, W., Pagé, N., Chakir, J., & Hamid, Q. A. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.01980.x · Cited by 31

The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery

Evans, M. J., Fanucchi, M. V., Baker, G. L., Winkle, L. S. V., Pantle, L. M., Nishio, S. J., Schelegle, E. S., Gershwin, L. J., Miller, L. A., Hyde, D. M., et al. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.02004.x · Cited by 31

Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes

Johnson, J. R., Świrski, F. K., Gajewska, B., Wiley, R. E., Fattouh, R., Pacitto, S. R., Wong, J. K., Stämpfli, M. R., & Jordana, M. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00056.2007 · Cited by 31

Calpain‐activated mTORC2/Akt pathway mediates airway smooth muscle remodelling in asthma

Rao, S., Mu, Q., Zeng, Y., Cai, P. C., Liu, F., Yang, J., Xia, Y., Zhang, Q., Song, L. ‐., Zhou, L., et al. (2016) · Clinical & Experimental Allergy · doi:10.1111/cea.12805 · Cited by 31

Inhaled Salmeterol/Fluticasone Propionate

Reynolds, N. A., Lyseng-Williamson, K. A., & Wiseman, L. R. (2005) · Drugs · doi:10.2165/00003495-200565120-00012 · Cited by 31

Bulbus Fritillariae Cirrhosae as a Respiratory Medicine: Is There a Potential Drug in the Treatment of COVID-19?

Quan, Y., Li, L., Yin, Z., Chen, S., Yi, J., Lang, J., Zhang, L., Yue, Q., & Zhao, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.784335 · Cited by 30

Gasdermin D silencing alleviates airway inflammation and remodeling in an ovalbumin-induced asthmatic mouse model

Wu, J., Wang, P., Xie, X., Yang, X., Tang, S., Zhao, J., Liu, T., Wang, J., Zhang, J., Xia, T., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06777-5 · Cited by 30

Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience

Bonsignore, M. R., Profita, M., Gagliardo, R. P., Riccobono, L., Chiappara, G., Pace, E., & Gjomarkaj, M. (2015) · European Respiratory Review · doi:10.1183/09059180.10011114 · Cited by 30

Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

Cloots, R. H. E., Sankaranarayanan, S., Poynter, M. E., Terwindt‐Rouwenhorst, E., van Dijk, P., Lamers, W. H., & Köhler, E. S. (2017) · BMC Pulmonary Medicine · doi:10.1186/s12890-017-0490-7 · Cited by 30

Experimental and clinical studies on the effects of Portulaca oleracea L. and its constituents on respiratory, allergic, and immunologic disorders, a review

Khazdair, M. R., Saadat, S., Aslani, M. R., Shakeri, F., & Boskabady, M. H. (2021) · Phytotherapy Research · doi:10.1002/ptr.7268 · Cited by 30

CCL11 and GM-CSF Differentially Use the Rho GTPase Pathway to Regulate Motility of Human Eosinophils in a Three-Dimensional Microenvironment

Muessel, M. J., Scott, K. S., Friedl, P., Bradding, P. H., & Wardlaw, A. J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.12.8354 · Cited by 30

Timothy grass pollen extract‐induced gene expression and signalling pathways in airway epithelial cells

Röschmann, K., Luiten, S., Jonker, M. J., Breit, T. M., Fokkens, W. J., Petersen, A., & van Drunen, C. M. (2011) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2011.03713.x · Cited by 30

Epithelium Expression and Function of Retinoid Receptors in Asthma

Druilhe, A., Zahm, J., Benayoun, L., Mehdi, D. E., Grandsaigne, M., Dombret, M.-C., Mosnier, I., Feger, B., Depondt, J., Aubier, M., et al. (2007) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2006-0453oc · Cited by 30

Effects of specific prostanoid EP receptor agonists on cell proliferation and intracellular Ca2+ concentrations in human airway smooth muscle cells

Mori, A., Ito, S., Morioka, M., Aso, H., Kondo, M., Sokabe, M., & Hasegawa, Y. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.03.001 · Cited by 30

Montelukast and bronchial inflammation in asthma: A randomised, double-blind placebo-controlled trial

Ramsay, C. F., Sullivan, P., Gizycki, M. J., Wang, D., Swern, A. S., Barnes, N., Reiss, T. F., & Jeffery, P. K. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2009.01.019 · Cited by 30

Cross-Talk between Human Mast Cells and Bronchial Epithelial Cells in Plasminogen Activator Inhibitor-1 Production via Transforming Growth Factor-β1

Cho, S., Lee, S. H., Kato, A., Takabayashi, T., Kulka, M., Shin, S. C., & Schleimer, R. P. (2014) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2013-0399oc · Cited by 30

Allergic respiratory diseases in the elderly

Todo‐Bom, A. M., & Mota‐Pinto, A. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2009.06.003 · Cited by 30

Nitric oxide paradox in asthma

Keller, A. C., Rodriguez, D., & Russo, M. (2005) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762005000900005 · Cited by 30

Age of onset and the characteristics of asthma

Jeng‐Yuan, H. S. U., King, S. I., Kuo, B. I.-T., & Chiang, C. (2004) · Respirology · doi:10.1111/j.1440-1843.2004.00572.x · Cited by 30

Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice

Lee, K. S., Kim, S. R., Park, H. S., Park, S. J., Min, K. H., Lee, K. Y., Jin, S. M., & Lee, Y. C. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.09.001 · Cited by 30

Bronchial hyperresponsiveness: too complex to be useful?

Joos, G. (2003) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(03)00046-8 · Cited by 30

Emerging treatments for asthma

Blease, K., Lewis, A., & Raymon, H. K. (2003) · Expert Opinion on Emerging Drugs · doi:10.1517/14728214.8.1.71 · Cited by 30

Future treatments of allergic diseases and asthma

Stirling, R. G., & Chung, K. F. (2000) · British Medical Bulletin · doi:10.1258/0007142001903526 · Cited by 30

The bronchial epithelium: translating gene and environment interactions in asthma

Davies, D. E. (2001) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/01.all.0000010987.09561.65 · Cited by 30

Fenretinide Prevents Inflammation and Airway Hyperresponsiveness in a Mouse Model of Allergic Asthma

Kanagaratham, C., Kalivodová, A., Najdekr, L., Friedecký, D., Adam, T., Hajdúch, M., Sanctis, J. B. D., & Radzioch, D. (2014) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2014-0121oc · Cited by 29

Asthma Linked with Rhinosinusitis: An Extensive Review

Frieri, M. (2014) · Allergy & Rhinology · doi:10.2500/ar.2014.5.0083 · Cited by 29

Reduced airway inflammation in CD26/DPP4‐deficient F344 rats is associated with altered recruitment patterns of regulatory T cells and expression of pulmonary surfactant proteins

Schmiedl, A., Krainski, J., Schwichtenhövel, F., Schade, J., Klemann, C., Raber, K. A., Zscheppang, K., Beekmann, T., Acevedo, C., Glaab, T., et al. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2010.03547.x · Cited by 29

Mometasone furoate: an effective anti-inflammatory with a well-defined safety and tolerability profile in the treatment of asthma

Bousquet, J. (2009) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2009.02003.x · Cited by 29

Isatin down-regulates expression of atrial natriuretic peptide receptor A and inhibits airway inflammation in a mouse model of allergic asthma

Kandasamy, R., Park, S. J., Boyapalle, S., Mohapatra, S. S., Hellermann, G., Lockey, R. F., & Mohapatra, S. S. (2009) · International Immunopharmacology · doi:10.1016/j.intimp.2009.11.003 · Cited by 29

Results of an Asthma Disease Management Program in an Urban Pediatric Community Clinic

Newcomb, P. (2006) · Journal for Specialists in Pediatric Nursing · doi:10.1111/j.1744-6155.2006.00064.x · Cited by 29

The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite

Shang, V., O’Sullivan, S. E., Kendall, D. A., & Roberts, R. E. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.01.023 · Cited by 29

Lung Function, Inflammation, and Endothelin‐1 in Congenital Heart Disease–Associated Pulmonary Arterial Hypertension

Low, A., George, S. J., Howard, L., Bell, N., Millar, A., & Tulloh, R. M. R. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.007249 · Cited by 29

Which Factors Associated With Activated Eosinophils Contribute to the Pathogenesis of Aspirin-Exacerbated Respiratory Disease?

Choi, Y., Lee, Y., & Park, H. (2019) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2019.11.3.320 · Cited by 29

A Prodrug of Cysteine, l-2-Oxothiazolidine-4-carboxylic Acid, Regulates Vascular Permeability by Reducing Vascular Endothelial Growth Factor Expression in Asthma

Lee, K. S., Park, H. S., Park, S. J., Kim, S. R., Min, K. H., Jin, S. M., Park, K., Kim, U., Kim, C. Y., & Lee, Y. C. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.016055 · Cited by 29

Allergy as a global problem: ‘Think globally, act globally’

Bousquet, J. (2002) · Allergy · doi:10.1034/j.1398-9995.2002.02002.x · Cited by 29

Calcitonin Gene-Related peptide receptor antagonist suppresses allergic asthma responses via downregulation of group 2 innate lymphoid cells in mice

Ike, E., Kawano, T., Takahashi, K., Miyasaka, T., & Takahashi, T. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110608 · Cited by 28

Tiotropium may improve asthma symptoms and lung function in asthmatic patients with irreversible airway obstruction: the real‐life data

Abadoğlu, Ö., & Berk, S. (2014) · The Clinical Respiratory Journal · doi:10.1111/crj.12230 · Cited by 28

Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle

Roscioni, S. S., Prins, A. G., Elzinga, C. R. S., Menzen, M. H., Dekkers, B. G. J., Halayko, A. J., Meurs, H., Maarsingh, H., & Schmidt, M. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01354.x · Cited by 28

Antiallergic and antihistaminic actions of Ceasalpinia bonducella seeds: Possible role in treatment of asthma

Vikhe, S. R., & Nirmal, S. A. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.12.007 · Cited by 28

Wheezing phenotypes and risk factors in early life: The ELFE cohort

Hallit, S. R., Leynaert, B., Delmas, M. C., Rocchi, S., Jacques de, B. L. I. C., Marguet, C., Scherer, É., Dufourg, M., Bois, C., Reboux, G., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0196711 · Cited by 32

The Changing Asthma Management Landscape and Need for Appropriate SABA Prescription

Domingo, C., & Singh, D. (2023) · Advances in Therapy · doi:10.1007/s12325-022-02410-z · Cited by 28

Naringenin inhibits allergen-induced airway remodeling in a murine model of asthma

Shi, Y., Tan, Y. L., MAO, S., & Gu, W. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.1940 · Cited by 28

Pin1–FADD Interactions Regulate Fas-Mediated Apoptosis in Activated Eosinophils

Oh, J., & Malter, J. S. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202646 · Cited by 28

Analyzing Serum Eosinophil Cationic Protein in the Clinical Assessment of Chronic Rhinosinusitis

Kim, K. S., Won, H.-R., Park, C. Y., Hong, J. H., Lee, J. H., Lee, K. E., Cho, H. S., & Kim, H. J. (2013) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2013.27.3901 · Cited by 28

Up-regulation of KCa3.1 promotes human airway smooth muscle cell phenotypic modulation

Yu, Z., Wang, Y.-X., Song, Y. J., Lü, H., Hou, L.-N., Cui, Y.-Y., & Chen, H.-Z. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2013.09.002 · Cited by 28

Multi-allergen Challenge Stimulates Steriod-Resistant Airway Inflammation via NF-κB-Mediated IL-8 Expression

Liu, R., Bai, J., Xu, G., Xuan, L., Zhang, T., Meng, A., & Hou, Q. (2013) · Inflammation · doi:10.1007/s10753-013-9611-5 · Cited by 28

The Role of Hypoxia-Inducible Factor 1α in Allergic Rhinitis

Mo, J., Kim, J.-H., Lim, D. J., & Kim, E. H. (2014) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2014.28.4025 · Cited by 28

Impact of bacterial infections on airway diseases: FIGURE 1.

Toews, G. B. (2005) · European Respiratory Review · doi:10.1183/09059180.05.00009504 · Cited by 28

Estrogen Receptor β: Expression Profile and Possible Anti-Inflammatory Role in Disease

Catley, M. C., Birrell, M. A., Hardaker, E. L., Alba, J. D., Farrow, S. N., Haj‐Yahia, S., & Belvisi, M. G. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.136275 · Cited by 28

Children with stable asthma have reduced airway matrix metalloproteinase‐9 and matrix metalloproteinase‐9/tissue inhibitor of metalloproteinase‐1 ratio

Doherty, G. M., Kamath, S. V., de Courcey, F., Christie, S. N., Chisakuta, A. M., Lyons, J. D., Heaney, L. G., Ennis, M., & Shields, M. D. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02326.x · Cited by 28

The Effect of Inhaled Budesonide and Formoterol on Bronchial Remodeling and HRCT Features in Young Asthmatics

Capraz, F., Kunter, E., Çermık, H., Ïlvan, A., & Poçan, S. (2007) · Lung · doi:10.1007/s00408-006-0007-2 · Cited by 28

Correction: Control of Allergen-Induced Inflammation and Hyperresponsiveness by the Metalloproteinase ADAMTS-12

Paulissen, G., Hour, M. E., Rocks, N., Gueders, M. M., Bureau, F., Foidart, J.-M., López-Otı́n, C., Noël, A., & Cataldo, D. D. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2100809 · Cited by 28

Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function

Clifford, R. L., Singer, C. A., & John, A. E. (2012) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2012.07.002 · Cited by 27

Biomarker discovery in asthma and COPD by proteomic approaches

Rossi, R., Palma, A. D., Benazzi, L., Riccio, A., Canonica, G. W., & Mauri, P. (2014) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201300108 · Cited by 27

Liposomal Retinoic Acids Modulate Asthma Manifestations in Mice ,

Maret, M., Ruffié, C., Périquet, B., Campo, A.-M., Menevret, M., Phelep, A., Dziewiszek, K., Druilhe, A., & Pretolani, M. (2007) · Journal of Nutrition · doi:10.1093/jn/137.12.2730 · Cited by 27

Severe asthma: anti-IgE or anti-IL-5?

Papathanassiou, E., Loukides, S., & Bakakos, P. (2016) · European Clinical Respiratory Journal · doi:10.3402/ecrj.v3.31813 · Cited by 27

Classification of chemicals as respiratory allergens based on human data: Requirements and practical considerations

Pemberton, M., & Kimber, I. (2021) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2021.104925 · Cited by 28

In vivo relationship between collagenase‐2 and interleukin‐8 but not tumour necrosis factor‐α in chronic rhinosinusitis with nasal polyposis

Kostamo, K., Sorsa, T. A., Leino, M. S., Tervahartiala, T. I., Alenius, H. T., Richardson, M. D., & Тоскала, Е. (2005) · Allergy · doi:10.1111/j.1398-9995.2005.00888.x · Cited by 27

Asthma Treatment Outcome in Children Is Associated with Vascular Endothelial Growth Factor A (VEGFA) Polymorphisms

Balantic, M., Rijavec, M., Kavalar, M. S., Šuškovič, S., Šilar, M., Košnik, M., & Korošec, P. (2012) · Molecular Diagnosis & Therapy · doi:10.1007/bf03262206 · Cited by 27

Elastin in asthma

Reddel, C. J., Weiss, A. S., & Burgess, J. K. (2012) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2012.02.001 · Cited by 28

AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma

Ji, P., Hu, H., Yang, X., Wei, X., Zhu, C., Liu, J., Feng, Y., Yang, F., Okanurak, K., Li, N., et al. (2014) · Parasitology Research · doi:10.1007/s00436-014-4223-z · Cited by 27

Air Pollution and Serum C-reactive Protein Concentration in Children

Shima, M. (2007) · Journal of Epidemiology · doi:10.2188/jea.17.169 · Cited by 27

Interleukin‐1β attenuates endothelin B receptor‐mediated airway contractions in a murine in vitro model of asthma: roles of endothelin converting enzyme and mitogen‐activated protein kinase pathways

Zhang, Y., Mikael Adner, A., & Cardell, L. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.02040.x · Cited by 27

Chronic inflammation in asthma: a contest of persistence vs resolution

Hove, C. L. V., Maes, T., Joos, G., & Tournoy, K. G. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01772.x · Cited by 28

Growing old with asthma: what are the changes and challenges?

Braman, S. S. (2010) · Expert Review of Respiratory Medicine · doi:10.1586/ers.10.12 · Cited by 27

Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation

Ilmarinen, P., Moilanen, E., & Kankaanranta, H. (2010) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2010.04.001 · Cited by 27

Suppression of Eosinophil Integrins Prevents Remodeling of Airway Smooth Muscle in Asthma

Januškevičius, A., Gosens, R., Sakalauskas, R., Vaitkienė, S., Janulaitytė, I., Halayko, A. J., Hoppenot, D., & Malakauskas, K. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2016.00680 · Cited by 27

Childhood and Parental Asthma, Future Risk of Bipolar Disorder and Schizophrenia Spectrum Disorders: A Population-Based Cohort Study

Wu, Q., Dalman, C., Karlsson, H., Lewis, G., Osborn, D., Gardner, R. M., & Hayes, J. (2018) · Schizophrenia Bulletin · doi:10.1093/schbul/sby023 · Cited by 27

Correlation of bronchoalveolar eosinophilic percentage with airway responsiveness in cats with chronic bronchial disease

Allerton, F., Leemans, J., Tual, C., Bernaerts, F., Kirschvink, N. A., & Clercx, C. (2013) · Journal of Small Animal Practice · doi:10.1111/jsap.12070 · Cited by 27

Airway function, oedema, cell infiltration and nitric oxide generation in conscious ozone‐exposed guinea‐pigs: effects of dexamethasone and rolipram

Toward, T. J., & Broadley, K. J. (2002) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704764 · Cited by 27

Reversal of established CD4+ type 2 T helper‐mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling

Jarman, E. R., & Lamb, J. R. (2004) · Immunology · doi:10.1111/j.1365-2567.2004.01927.x · Cited by 27

Risk factors related to fixed airway obstruction in patients with asthma after antiasthma treatment

Jang, A., Lee, J.-H., Park, S., Park, J., Kim, D.-J., & Park, C. (2007) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)60564-9 · Cited by 27

Effects of childhood respiratory diseases on the anatomical and functional development of the respiratory system

Merkus, P. J. F. M. (2003) · Paediatric Respiratory Reviews · doi:10.1016/s1526-0542(02)00311-1 · Cited by 27

The bronchial epithelium in chronic and severe asthma

Davies, D. E. (2001) · Current Allergy and Asthma Reports · doi:10.1007/s11882-001-0080-9 · Cited by 27

New immunological approaches and cytokine targetsin asthma and allergy

Stirling, R. G., & Chung, K. F. (2000) · European Respiratory Journal · doi:10.1034/j.1399-3003.2000.16f24.x · Cited by 27

A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma

Evans, R. L., Nials, A. T., Knowles, R. G., Kidd, E. J., Ford, W. R., & Broadley, K. J. (2012) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2012.08.004 · Cited by 27

Enhanced oral bioavailability and antiasthmatic efficacy of curcumin using redispersible dry emulsion

Jang, D.-J., Kim, S. T., Oh, E., & Lee, K. (2014) · Bio-Medical Materials and Engineering · doi:10.3233/bme-130886 · Cited by 26

Budesonide/formoterol for maintenance and reliever therapy in the management of moderate to severe asthma

Humbert, M. J. C., Andersson, T. L. G., & Buhl, R. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01863.x · Cited by 26

Effects of combined vanadate and magnesium treatment on erythrocyte antioxidant defence system in rats

Ścibior, A., & Zaporowska, H. (2010) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2010.05.003 · Cited by 26

Antioxidant and antiasthmatic effects of saucerneol D in a mouse model of airway inflammation

Jung, J., Lee, K., Lee, M.-Y., Jung, D.-Y., Cho, E.-S., & Son, H. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.01.015 · Cited by 26

Remodeling of extra-bronchial lung vasculature following allergic airway inflammation

Rydell‐Törmänen, K., Uller, L., & Erjefalt, J. S. (2008) · Respiratory Research · doi:10.1186/1465-9921-9-18 · Cited by 26

Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA)-power plant studies: assessment of cellular responses

Godleski, J. J., Diaz, E. A., Lemos, M., Long, M. S., Ruiz-Rudolph, P., Gupta, T., Kang, C., & Coull, B. A. (2011) · Inhalation Toxicology · doi:10.3109/08958378.2010.563804 · Cited by 26

Role of A Disintegrin And Metalloprotease-12 in Neutrophil Recruitment Induced by Airway Epithelium

Estrella, C., Rocks, N., Paulissen, G., Quesada‐Calvo, F., Noël, A., Vilain, E., Lassalle, P., Tillie‐Leblond, I., Cataldo, D. D., & Gosset, P. (2009) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0124oc · Cited by 26

Infliximab alleviates inflammation and ex vivo airway hyperreactivity in asthmatic E3 rats

Cai, Y., Cao, Y., Lu, S., Xu, C., & Cardell, L. (2011) · International Immunology · doi:10.1093/intimm/dxr032 · Cited by 26

Bronchial Asthma, Chronic Obstructive Pulmonary Disease and NF-κB

Charokopos, N., Apostolopoulos, N., Kalapodi, M., Leotsinidis, M., Karamanos, N. K., & Mouzaki, Α. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709787549280 · Cited by 26

Airway factor XIII associates with type 2 inflammation and airway obstruction in asthmatic patients

Esnault, S. J., KELLY, E. A. B., Sorkness, R. L., Evans, M. D., Busse, W. W., & Jarjour, N. N. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.05.053 · Cited by 26

Drug Signature-based Finding of Additional Clinical Use of LC28-0126 for Neutrophilic Bronchial Asthma

Shin, E.-J., Lee, Y. C., Kim, S. R., Kim, S. H., & Park, J. (2015) · Scientific Reports · doi:10.1038/srep17784 · Cited by 26

In Vivo Allergen-Activated Eosinophils Promote Collagen I and Fibronectin Gene Expression in Airway Smooth Muscle Cells via TGF-β1 Signaling Pathway in Asthma

Janulaitytė, I., Januškevičius, A., Kalinauskaitė-Žukauskė, V., Bajoriūnienė, I., & Malakauskas, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051837 · Cited by 27

Long-Acting ??2-Agonists in Asthma

Currie, G. P., Lee, D. K. C., & Lipworth, B. J. (2006) · Drug Safety · doi:10.2165/00002018-200629080-00002 · Cited by 26

Effects of Nitrogen Dioxide on Allergic Airway Responses in Subjects With Asthma

Witten, A., Solomon, C., Abbritti, E. P., Arjomandi, M., Zhai, W., Kleinman, M. T., & Balmes, J. R. (2005) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000177081.62204.8d · Cited by 26

Low-density areas on high-resolution computed tomograms in chronic pediatric asthma

Pifferi, M., Caramella, D., Ragazzo, V., Pietrobelli, A., & Boner, A. L. (2002) · The Journal of Pediatrics · doi:10.1067/mpd.2002.125006 · Cited by 26

Lung Regeneration: Cells, Models, and MechanismsPreprint

Konkimalla, A., Tata, A., & Tata, P. R. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a040873 · Cited by 31

Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation

van der Velden, J. L. J., Hoffman, S. M., Alcorn, J. F., Tully, J. E., Chapman, D. G., Lahue, K. G., Guala, A. S., Lundblad, L. K. A., Aliyeva, M., Daphtary, N., et al. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00153.2013 · Cited by 26

Neutrophilic asthma has different radiographic features to COPD and smokers

Simpson, J. L., Milne, D. G., & Gibson, P. G. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2008.12.013 · Cited by 25

Levels of IL-32 in Serum, Induced Sputum Supernatant, and Bronchial Lavage Fluid of Patients with Chronic Obstructive Pulmonary Disease

Gasiūnienė, E., Lavinskienė, S., Sakalauskas, R., & Šitkauskienė, B. (2016) · COPD Journal of Chronic Obstructive Pulmonary Disease · doi:10.3109/15412555.2016.1145201 · Cited by 25

Rhinovirus Infection and Virus-Induced Asthma

Hayashi, Y., Sada, M., Shirai, T., Okayama, K., Kimura, R., Kondo, M., Okodo, M., Tsugawa, T., Ryo, A., & Kimura, H. (2022) · Viruses · doi:10.3390/v14122616 · Cited by 25

A role for WNT1-inducible signaling protein-1 in airway remodeling in a rat asthma model

Yang, M., Zhao, X., Liu, Y., Tian, Y., Ran, X., & Jiang, Y. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.06.011 · Cited by 25

Effect of Bronchoconstriction on Airway Remodeling in Asthma

(2018) · New England Journal of Medicine · doi:10.1056/nejmx180023 · Cited by 2

Airway Remodeling in Asthma: An Introduction

Nakagawa, T., & Hoshino, M. (2004) · Clinical Reviews in Allergy & Immunology · doi:10.1385/criai:27:1:001 · Cited by 7

Bronchoconstriction and Airway Remodeling

Brashier, B. B., Iyer, N., & Salvi, S. S. (2011) · New England Journal of Medicine · doi:10.1056/nejmc1107353 · Cited by 2

[Asthma: an inflammatory disease with remodeling of the respiratory tract].

Djukanović, R. (1997) · PubMed

Update on Airway Inflammation and Remodeling in Asthma

Hashimoto, S., Matsumoto, K., Gon, Y., Takahashi, N., Ichiwata, T., & Pawankar, R. (2007) · Allergy & Clinical Immunology International - Journal of the World Allergy Organization · doi:10.1027/0838-1925.19.5.178 · Cited by 8