Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling

Potential role for phenotypic modulation of bronchial smooth muscle ceils in chronic asthma

Halayko, A. J., & STEPHENS, N. L. (1994) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y94-209 · Cited by 64

Lung elastic recoil and reduced airflow in clinically stable asthma.

McCarthy, D. S., & Sigurdson, M. (1980) · Thorax · doi:10.1136/thx.35.4.298 · Cited by 64

Eosinophil cationic protein(ECP) and eosinophil protein X (EXP) concentrations in serum and bronchial lavage fluid in asthma. effect of prednisolone treatment.

Robinson, D. S., Assoufi, B., Durham, S. R., & Kay, A. B. (1995) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1995.tb03259.x · Cited by 63

Bronchial Epithelial Cells Produce Chemotactic Activity for Bronchial Epithelial Cells: Possible Role for Fibronectin in Airway Repair

Shoji, S., Ertl, R. F., Under, J., Berger, D. R., & Rennard, S. I. (1990) · American Review of Respiratory Disease · doi:10.1164/ajrccm/141.1.218 · Cited by 63

Cytokines in Bronchoalveolar Lavage Fluid of Patients With Nocturnal Asthma

Jarjour, N. N., & Busse, W. W. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.152.5.7582279 · Cited by 62

Inflammatory cells and eicosanoid mediators in subjects with late asthmatic responses and increases in airway responsiveness

Smith, H. R., Larsen, G. L., Cherniack, R. M., Wenzel, S. E., Voelkel, N. F., Westcott, J. Y., & Bethel, R. A. (1992) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(92)90291-9 · Cited by 62

Steroid resistant asthma: what is the clinical definition?

Woolcock, A. J. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06050743 · Cited by 61

Human alveolar macrophage activation: Inhibition by forskolin but not β-adrenoceptor stimulation or phosphodiesterase inhibition

Fuller, R. W., O'Malley, G. J., Baker, A. J., & MacDermot, J. (1988) · Pulmonary Pharmacology · doi:10.1016/s0952-0600(88)80006-1 · Cited by 61

Changes in bronchoalveolar lavage inflammatory cells in asthmatic patients treated with high dose inhaled beclomethasone dipropionate

Duddridge, M., Ward, C., Hendrick, D. J., & Walters, E. H. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06040489 · Cited by 61

Insulin-Like Growth Factor I is a Major Fibroblast Mitogen Produced by Primary Cultures of Human Airway Epithelial Cells

Cambrey, A. D., Kwon, O. J., Gray, A. J., Harrison, N. K., Yacoub, M. H., Barnes, P. J., Laurent, G. J., & Chung, K. F. (1995) · Clinical Science · doi:10.1042/cs0890611 · Cited by 60

Endothelin increases [Ca2+]i, protein phosphorylation, and O2-. production in human alveolar macrophages

Haller, H. G., Schaberg, T., Lindschau, C., Lode, H. M., & Distler, A. (1991) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1991.261.6.l478 · Cited by 60

Characteristics of Bronchial Asthma with Incomplete Reversibility of Airflow Obstruction

Hudson, C., Turcotte, H., Laviolette, M., Carrier, G., & Boulet, L. (1997) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)63387-x · Cited by 59

Cysteinyl leukotrienes enhance growth of human airway epithelial cells

Leikauf, G. D., Claesson, H., Doupnik, C. A., Hybbinette, S. S., & Grafström, R. (1990) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1990.259.4.l255 · Cited by 59

Differential effects of granulocyte-macrophage colony-stimulating factor on eosinophil and neutrophil superoxide anion generation

Nagata, M., Sedgwick, J. B., & Busse, W. W. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.10.4948 · Cited by 58

Pulmonary Function During Clinical Remission of Asthma How Reversible is Asthma?*

Cade, J. F., & PAIN, M. C. F. (1973) · Australian and New Zealand Journal of Medicine · doi:10.1111/j.1445-5994.1973.tb04293.x · Cited by 58

Role and mechanism of thromboxane-induced proliferation of cultured airway smooth muscle cells

Noveral, J. P., & Grunstein, M. M. (1992) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1992.263.5.l555 · Cited by 58

Low-affinity receptor for IgE on human bronchial epithelial cells in asthma.

Campbell, A., Vignola, A. M., Chanez, P., Godard, P., & Bousquet, J. (1994) · PubMed Central · Cited by 56

Viruses in asthma

Busse, W. W., & Gern, J. E. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70216-1 · Cited by 56

Decreased suppressor cell activity of alveolar macrophages in bronchial asthma.

Aubas, P., Cosso, B., Godard, P., Michel, F. B., & Clot, J. (1984) · PubMed · doi:10.1164/arrd.1984.130.5.875 · Cited by 56

Effect of interleukin-5 and granulocyte-macrophage colony stimulating factor on in vitro eosinophil function: Comparison with airway eosinophils

Sedgwick, J. B., Quan, S. G., Calhoun, W. J., & Busse, W. W. (1995) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(95)70057-9 · Cited by 55

Ventilatory Function in Subjects with Childhood Asthma who have Become Symptom Free

Blackhall, M. I. (1970) · Archives of Disease in Childhood · doi:10.1136/adc.45.241.363 · Cited by 55

Bronchial biopsies and airway inflammation

Jeffery, P. K. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09081583 · Cited by 55

Bronchial epithelial cells regulate fibroblast proliferation

Nakamura, Y., Tate, L., Ertl, R. F., Kawamoto, M., Mio, T., Adachi, Y., Romberger, D. J., Koizumi, S., Gossman, G. L., Robbins, R., et al. (1995) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1995.269.3.l377 · Cited by 55

Eosinophil degranulation in the presence of bronchial epithelial cells. Effect of cytokines and role of adhesion

Takafuji, S., Ohtoshi, T., Takizawa, H., Tadokoro, K., & Ito, K. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.156.10.3980 · Cited by 54

Modulation by the epithelium of the extent of bronchial narrowing produced by substances perfused through the lumen

Sparrow, M. P., & Mitchell, H. W. (1991) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1991.tb12317.x · Cited by 54

Endothelin: Systemic Arterial and Pulmonary Effects of a New Peptide with Potent Biologic Properties

Lüscher, T. F. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/146.5_pt_2.s56 · Cited by 54

The relationship between bronchial immunopathology and hyperresponsiveness in asthma

Poulter, L. W., Power, C. K., & Burke, C. M. (1990) · European Respiratory Journal · doi:10.1183/09031936.93.03070792 · Cited by 54

Lung Mechanics during Provocation of Asthma

Cade, J. F., Woolcock, A. J., Rebuck, A. S., & PAIN, M. C. F. (1971) · Clinical Science · doi:10.1042/cs0400381 · Cited by 54

Resolution of chronic inflammation by therapeutic induction of apoptosis

Anderson, G. P. (1996) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(96)01004-8 · Cited by 53

Platelet Kinetics in Stable Atopic Asthmatic Patients

Taytard, A., Guénard, H. J.-P., Vuillemin, L., Bouvot, J. L., Vergeret, J., Ducassou, D., Piquet, Y., & Fréour, P. (1986) · American Review of Respiratory Disease · doi:10.1164/arrd.1986.134.5.983 · Cited by 52

Repair mechanisms in asthma

Rennard, S. I. (1996) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(96)70076-3 · Cited by 52

The epithelial barrier and airway responsiveness

Sparrow, M. P., Mitchell, H. W., & Omari, T. I. (1995) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y95-027 · Cited by 52

The effect of inhaled sodium cromoglycate on cellular infiltration into the bronchial mucosa and the expression of adhesion molecules in asthmatics

Hoshino, M., & Nakamura, Y. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10040858 · Cited by 52

Ciliated cell damage in the bronchial epithelium of asthmatics and non‐asthmatics

Montefort, S., Djukanović, R., Holgate, S. T., & Roche, W. R. (1993) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1993.tb00880.x · Cited by 52

Mortality and Decline in Lung Function in 213 Adults with Bronchial Asthma: A Ten-Year Follow Up

Ulrik, C. S., Backer, V., & Dirksen, A. (1992) · Journal of Asthma · doi:10.3109/02770909209110638 · Cited by 51

Modulation of Fibronectin and Tenascin Production in Human Bronchial Epithelial Cells by Inflammatory Cytokines In Vitro

Härkönen, E., Virtanen, I., Linnala, A., LAITINEN, L., & Kinnula, V. L. (1995) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.13.1.7541219 · Cited by 50

Neutrophils Recruited to the Lungs of Humans by Segmental Antigen Challenge Display a Reduced Chemotactic Response to Leukotriene B4

Koh, Y. Y., Dupuis, R., Pollice, M., Albertine, K. H., Fish, J. E., & Peters, S. P. (1993) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb/8.5.493 · Cited by 50

MECHANISMS OF INCREASED AIRWAY MICROVASCULAR PERMEABILITY: ROLE IN AIRWAY INFLAMMATION AND OBSTRUCTION

Goldie, R. G., & Pedersen, K. E. (1995) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.1995.tb02028.x · Cited by 50

Interleukin-5 mRNA in Mucosal Bronchial Biopsies from Asthmatic Subjects

Hamid, Q. A., Azzawi, M., Sun, Y., Moqbel, R., Wardlaw, A. J., Corrigan, C. J., Bradley, B., Durham, S. R., Collins, J. V., Jeffery, P. K., et al. (2009) · International Archives of Allergy and Applied Immunology · doi:10.1159/000235353 · Cited by 49

Pulmonary immune cells in health and disease: dendritic cells and Langerhans' cells

Hance, A. J. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06081213 · Cited by 49

Comparison of the immunopathology of extrinsic, intrinsic and occupational asthma.

Bentley, A. M., Durham, S. R., & Kay, A. B. (1995) · PubMed · Cited by 49

Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction

Aubert, J., Hayashi, S., Hards, J. M., Bai, T. R., Paré, P. D., & Hogg, J. C. (1994) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1994.266.6.l655 · Cited by 48

Activation by Histamine of Bronchial Epithelial Cells from Nonasthmatic Subjects

Vignola, A. M., Campbell, A., Chanez, P., Paul-Lacoste, P., Michel, F. B., Godard, P., & Bousquet, J. (1993) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb/9.4.411 · Cited by 47

Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents

Boulet, L., Boutet, M., Laviolette, M., Dugas, M., Milot, J., LeBlanc, C., Paquette, L., Cote, J., Cartier, A., & Malo, J. (1994) · European Respiratory Journal · doi:10.1183/09031936.94.07091567 · Cited by 47

Hydrogen peroxide contracts human airways in vitro: role of epithelium

Rabe, K. F., Dent, G., & MAGNUSSEN, H. (1995) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1995.269.3.l332 · Cited by 47

Lung myofibroblasts

Leslie, K. O., Mitchell, J., & Low, R. B. (1992) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.970220203 · Cited by 47

Inflammatory and T-Cell Profile of Asthmatic Airways 6 Hours After Local Allergen Provocation

Gratziou, C., Carroll, M., Montefort, S., Teran, L. M., Howarth, P. H., & Holgate, S. T. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.153.2.8564090 · Cited by 46

Inflammatory cell number and mediators in bronchoalveolar lavage fluid and peripheral blood in subjects with asthma with increased nocturnal airways narrowing

Oosterhoff, Y., Kauffman, H. F., Rutgers, B., Zijlstra, F. J., Koëter, G. H., & Postma, D. S. (1995) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(95)70011-0 · Cited by 46

The effects of theophylline on mucosal inflammation in asthmatic airways: biopsy results

Djukanović, R., Finnerty, J. P., Lee, C., Wilson, S. J., Madden, J., & Holgate, S. T. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08050831 · Cited by 45

Platelet‐derived growth factor in asthma

Chanez, P., Vignola, M., Stenger, R., Vic, P., Michel, F. B., & Bousquet, J. (1995) · Allergy · doi:10.1111/j.1398-9995.1995.tb02493.x · Cited by 45

Role of inflammation in nocturnal asthma.

Mackay, T. W., Wallace, W. A., Howie, S., Brown, P. H., Greening, A. P., Church, M. K., & Douglas, N. J. (1994) · Thorax · doi:10.1136/thx.49.3.257 · Cited by 45

Altered compartimentalization of transforming growth factor-beta in asthmatic airways

Magnan, A., Rétornaz, F., Tsicopoulos, A., Brisse, J., Pee, D. V., Gosset, P., Chamlian, A., Tonnel, A., & VERVLOET, D. (1997) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1997.tb00723.x · Cited by 44

Identification of elastase in human eosinophils: Immunolocalization, isolation, and partial characterization

Lungarella, G., Menegazzi, R., Gardi, C., Spessotto, P., Santi, M. M. D., Bertoncin, P., Patriarca, P., Calzoni, P., & Zabucchi, G. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90060-a · Cited by 44

Immunoglobulin E-mediated Increase in Vascular Permeability Correlates with Eosinophilic Inflammation

Collins, D. S., Dupuis, R., Gleich, G. J., Bartemes, K. R., Koh, Y. Y., Pollice, M., Albertine, K. H., Fish, J. E., & Peters, S. P. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/147.3.677 · Cited by 44

A seven-year follow-up study of 343 adults with bronchial asthma.

Almind, M., Viskum, K., Evald, T., Dirksen, A., & Kok‐Jensen, A. (1992) · PubMed · Cited by 44

Beta adrenergic modulation of formyl-methionine-leucine-phenylalanine-stimulated secretion of eosinophil peroxidase and leukotriene C4.

Muñoz, N. M., Vita, A. J., Neeley, S. P., McAllister, K., Spaethe, S. M., White, S. R., & Leff, A. R. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38457-0 · Cited by 43

Increased generation of the arachidonic metabolites LTB4 and 5-HETE by human alveolar macrophages in patients with asthma: effect in vitro of nedocromil sodium

Damon, M., Chavis, C., Daurès, J., de Paulet, A. C., Michel, F. B., & Godard, P. (1989) · European Respiratory Journal · doi:10.1183/09031936.93.02030202 · Cited by 43

Modulation of adhesion molecule expression on endothelial cells during the late asthmatic reaction: role of macrophage-derived tumour necrosis factor-alpha

Lassalle, P., Gosset, P., Delneste, Y., Tsicopoulos, A., Capron, A., Joseph, M., & Tonnel, A. (1993) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1993.tb05985.x · Cited by 43

Theophylline, a new inducer of apoptosis in B‐CLL: role of cyclic nucleotides

Mentz, F., Merle‐Béral, H., Ouaaz, F., & Binet, J. (1995) · British Journal of Haematology · doi:10.1111/j.1365-2141.1995.tb05225.x · Cited by 43

Lung recoil and the determination of airflow limitation in cystic fibrosis and asthma

Zapletal, A., Desmond, K. J., Demizio, D., & Coates, A. L. (1993) · Pediatric Pulmonology · doi:10.1002/ppul.1950150103 · Cited by 42

The distribution of adhesive mechanisms in the normal bronchial epithelium

Montefort, S., Baker, J. E., Roche, W. R., & Holgate, S. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06091257 · Cited by 42

Airway and lung elastic fibre is not reduced in asthma nor in asthmatics following corticosteroid treatment

Godfrey, R. W. A., Lorimer, S. M., Majumdar, S., Adelroth, E. C., Johnston, P., Rogers, A., Johansson, S.-A., & Jeffery, P. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08060922 · Cited by 41

Analysis of Plasma-Protein Leakage and Local Secretion in Sputum from Patients with Asthma and Chronic Obstructive Pulmonary Disease

Schoonbrood, D. F., Lutter, R., Habets, F., Roos, C. M., Jansen, H. M., & Out, T. A. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.150.6.7952610 · Cited by 41

3. Epithelial Cells: Barrier Functions and Shedding-Restitution Mechanisms

Persson, C. G. A. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm/153.6_pt_2.s9 · Cited by 41

Leukotriene C4 upregulates collagenase expression and synthesis in human lung fibroblasts

Medina, L., Pérez‐Ramos, J., Ramı́rez, R., Selman, M., & Pardo, A. (1994) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(94)90187-2 · Cited by 40

High resolution computed tomography in asthma

Mclean, A. N., Sproule, M., Cowan, M. D., & Thomson, N. C. (1998) · Thorax · doi:10.1136/thx.53.4.308 · Cited by 40

Cell cultures from bronchial subepithelial myofibroblasts enhance eosinophil survival in vitro

Zhang, S., Mohammed, Q., Burbidge, A., Morland, C., & Roche, W. R. (1996) · European Respiratory Journal · doi:10.1183/09031936.96.09091839 · Cited by 40

Airway permeability

Persson, C. G. A., Andersson, M., Greiff, L., SVENSSON, C., Erjefalt, J. S., Sundler, F., Wollmer, P., Alkner, U., Erjefält, I., Gustafsson, B., et al. (1995) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1995.tb00022.x · Cited by 40

Effect of inhaled glucocorticoids on IL-1 beta and IL-1 receptor antagonist (IL-1 ra) expression in asthmatic bronchial epithelium

Sousa, A. R., Trigg, C. J., Lane, S. J., Hawksworth, R. J., Nakhosteen, J. A., Poston, R. N., & Lee, T. H. (1997) · Thorax · doi:10.1136/thx.52.5.407 · Cited by 39

Cyclosporine A Inhibits Airway Reactivity and Remodeling After Chronic Antigen Challenge in Cats

Padrid, P. A., Cozzi, P., & Leff, A. R. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.6.8970375 · Cited by 38

Transforming Growth Factor β1 Preferentially Induces Apoptotic Cell Death in Rat Hepatocytes Cultured under Pericentral-Equivalent Conditions

Ohno, K. J., Ammann, P., Fasciati, R., & Maier, P. (1995) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1995.1103 · Cited by 38

The Role of Respiratory Infections in Airway Hyperresponsiveness and Asthma

Busse, W. W. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm/150.5_pt_2.s77 · Cited by 37

The role of the bone marrow in allergy and asthma

Denburg, J. A., Inman, M. D., Leber, B. F., Sehmi, R., & O’Byrne, P. M. (1996) · Allergy · doi:10.1111/j.1398-9995.1996.tb04578.x · Cited by 37

Mast Cells and Fibrosis—Who's on First?

Jordana, M. (1993) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb/8.1.7 · Cited by 37

Plasma exudation and solute absorption across the airway mucosa

Greiff, L., Erjefäl, I., SVENSSON, C., Wollmer, P., Alkner, U., Andersson, M., & Persson, C. G. A. (1993) · Clinical Physiology · doi:10.1111/j.1475-097x.1993.tb00322.x · Cited by 36

Peptidase Modulation of Airway Effects of Neuropeptides

Lilly, C. M., Drazen, J. M., & Shore, S. A. (1993) · Experimental Biology and Medicine · doi:10.3181/00379727-203-43616 · Cited by 36

Bronchial hyperreactivity to sulfur dioxide: physiologic and political implications

Boushey, H. A. (1982) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(82)90142-7 · Cited by 36

The relationship between bronchial responsiveness to methacholine and bronchial responsiveness to histamine in asthmatic subjects

Connolly, M. J., Avery, A. J., Walters, E. H., & Hendrick, D. J. (1988) · Pulmonary Pharmacology · doi:10.1016/0952-0600(88)90011-7 · Cited by 36

Lymphocyte and Macrophage Activation in Bronchoalveolar Lavage Fluid in Nocturnal Asthma

Oosterhoff, Y., Hoogsteden, H. C., Rutgers, B., Kauffman, H. F., & Postma, D. S. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.151.1.7812576 · Cited by 36

Effect of Salbutamol, Fenoterol, and Sodium Cromoglycate on the Release of Heparin from Sensitized Human Lung Fragments Challenged with Dermatophagoides pteronyssinus Allergen

GREEN, W. F., Konnaris, K., & Woolcock, A. J. (1993) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb/8.5.518 · Cited by 35

Blood and Bronchoalveolar Lavage Endothelin-1 Levels in Nocturnal Asthma

Kraft, M., Beam, W. R., Wenzel, S. E., Zamora, M. R., OʼBrien, R. F., & Rj, M. (1994) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.149.4.8143060 · Cited by 34

Involvement of endothelin in mononuclear phagocyte inflammation in asthma

Chanez, P., Vignola, A. M., Albat, B., Springall, D. R., Polak, J. M., Godard, P., & Bousquet, J. (1996) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(96)70166-5 · Cited by 34

Respiratory Symptoms in Young Adults Should Not Be Overlooked

Jaakkola, M. S., Jaakkola, J. J. K., Ernst, P., & Becklake, M. R. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/147.2.359 · Cited by 32

Abnormalities of lung mechanics in young asthmatic children.

Greenough, A., Loftus, B. G., Pool, J., & Price, J. F. (1987) · Thorax · doi:10.1136/thx.42.7.500 · Cited by 32

Contraction of human bronchial smooth muscle caused by activated human eosinophils

Rabe, K. F., Muñoz, N. M., Vita, A. J., Morton, B. E., MAGNUSSEN, H., & Leff, A. R. (1994) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1994.267.3.l326 · Cited by 32

Increased number of activated lymphocytes in human lung following swine dust inhalation

Müller-Suur, C., Larsson, K., Malmberg, P., & Larsson, P. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10020376 · Cited by 31

Epithelium-derived inhibitory prostaglandins modulate human bronchial smooth muscle responses to histamine

Knight, D. A., Stewart, G. A., Lai, M. L., & Thompson, P. J. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)00601-3 · Cited by 30

Leukotrienes as mediators of airway obstruction and inflammation in asthma

Dahlén, B., & Dahlén, S. (1995) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1995.tb00422.x · Cited by 29

Differential regulation of protease and extracellular matrix protein expression by transforming growth factor-beta 1 in non-small cell lung cancer cells and normal human bronchial epithelial cells

Jakowlew, S. B., Mariano, J. M., You, L., & Mathias, A. (1997) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(97)00068-7 · Cited by 29

Myofibroblast and elastic and collagen fiber hyperplasia in the bronchial mucosa: a possible basis for the progressive irreversibility of airway obstruction in chronic asthma.

Gabbrielli, S., Di Lollo, S., Stanflin, N., & Romagnoli, P. (1994) · PubMed · Cited by 29

Release of PAF-acether from human blood monocytes

ARNOUX, B., Jouvin‐Marche, E., Arnoux, A., & Benveniste, J. (1982) · Inflammation Research · doi:10.1007/bf01965089 · Cited by 28

Bronchial gland duct ectasia in fatal bronchial asthma: association with interstitial emphysema.

Cluroe, A. D., Holloway, L., Thomson, K., Purdie, G., & Beasley, R. W. (1989) · Journal of Clinical Pathology · doi:10.1136/jcp.42.10.1026 · Cited by 28

Hypereosinophilic syndromes: association with vasculitis, fibrosis and autoimmunity

Hall, F., & Walport, M. J. (1993) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1993.tb00892.x · Cited by 28

The role of allergy and atopy in asthma.

Platts‐Mills, T. A. E., & Lm, W. (1996) · PubMed · Cited by 28

Modulation by interleukin-4 of cytokine release from mononuclear phagocytes in asthma

Chanez, P., Vignola, A. M., Paul‐Eugène, N., Dugas, B., Godard, P., Michel, F. B., & Bousquet, J. (1994) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(94)90118-x · Cited by 27

Chapter 1: Definition, Diagnosis, and Classification

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