The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Endogenous Nitric Oxide in Single Exhalations and the Change during Exercise
Abstract
The concentrations of endogenous nitric oxide (NO) and CO2 were measured in exhaled air from healthy humans. During a single exhalation, NO concentrations peaked when the CO2 level reached its plateau. However, whereas CO2 levels remained at a plateau throughout the exhalation, NO concentrations declined after having peaked. After breathholding (5 to 60 s) NO peaked at a higher level than during normal breathing. Nitric oxide concentrations in exhaled air decreased during physical exercise (50 to 100 W). However, taking the increased ventilatory minute volume into account, excretion of NO markedly increased during exercise. The data are compatible with the hypothesis that the NO detected in exhaled air is formed preferentially in the terminal and respiratory bronchioles, and they suggest increased production of NO into exhaled air during exercise and during hyperventilation at rest.
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Citations
Cites
Nitric oxide: physiology, pathophysiology, and pharmacology.
Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525
Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans
Gustafsson, L. E., Leone, A. M., Persson, M. G., Wiklund, N. P., & Moncada, S. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91268-h · Cited by 964
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Cited by
(2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200406-710st · Cited by 3,203
(1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.6.ats8-99 · Cited by 771
Nitric oxide metabolism and breakdown
Kelm, M. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00020-1 · Cited by 673
Kharitonov, S., Alving, K., & Barnes, P. (1997) · European Respiratory Journal · doi:10.1183/09031936.97.10071683 · Cited by 664
Single-breath nitric oxide measurements in asthmatic patients and smokers
Persson, M. G., Gustafsson, L. E., Zetterström, O., Agrenius, V., & Ihre, E. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90935-0 · Cited by 483
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Metadata
- Authors
- Persson, M. G., Wiklund, N. P., & Gustafsson, L. E.
- Venue
- American Review of Respiratory Disease
- Publisher
- Oxford University Press (OUP)
- Published
- 1993-11
- Volume
- 148
- Issue
- 5
- Pages
- 1210-1214
- ISSN
- 0003-0805 (ISSN-L)
- OpenAlex
- W2079131490
- Cited by
- 209
- References
- 2
- FWCI
- 9.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Persson, M. G., Wiklund, N. P., & Gustafsson, L. E. (1993). Endogenous Nitric Oxide in Single Exhalations and the Change during Exercise. American Review of Respiratory Disease. https://doi.org/10.1164/ajrccm/148.5.1210
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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