The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Future Research Directions in Acute Lung Injury: Summary of a National Heart, Lung, and Blood Institute Working Group
Abstract
Acute lung injury (ALI) and its more severe form, the acute respiratory distress syndrome (ARDS), are syndromes of acute respiratory failure that result from acute pulmonary edema and inflammation. The development of ALI/ARDS is associated with several clinical disorders including direct pulmonary injury from pneumonia and aspiration as well as indirect pulmonary injury from trauma, sepsis, and other disorders such as acute pancreatitis and drug overdose. Although mortality from ALI/ARDS has decreased in the last decade, it remains high. Despite two major advances in treatment, low VT ventilation for ALI/ARDS and activated protein C for severe sepsis (the leading cause of ALI/ARDS), additional research is needed to develop specific treatments and improve understanding of the pathogenesis of these syndromes. The NHLBI convened a working group to develop specific recommendations for future ALI/ARDS research. Improved understanding of disease heterogeneity through use of evolving biologic, genomic, and genetic approaches should provide major new insights into pathogenesis of ALI. Cellular and molecular methods combined with animal and clinical studies should lead to further progress in the detection and treatment of this complex disease.
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Cites
(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941
The Acute Respiratory Distress Syndrome
Ware, L. B., & Matthay, M. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421806 · Cited by 4,666
Self-citationUse of proteomic patterns in serum to identify ovarian cancer
Petricoin, E. F., Ardekani, A. M., Hitt, B. A., Levine, P. J., Fusaro, V. A., Steinberg, S. M., Mills, G. B., Simone, C., Fishman, D. A., Kohn, E. C., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07746-2 · Cited by 3,236
Cytokine Balance in the Lungs of Patients with Acute Respiratory Distress Syndrome
PARK, W. Y., GOODMAN, R. B., STEINBERG, K. P., RUZINSKI, J. T., RADELLA, F., PARK, D. R., PUGIN, J., SKERRETT, S. J., HUDSON, L. D., & MARTIN, T. R. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.10.2104013 · Cited by 547
Pharmacological stimulation of the cholinergic antiinflammatory pathway
Bernik, T. R., Friedman, S. G., Ochani, M., DiRaimo, R., Ulloa, L., Yang, H., Sudan, S., Czura, C. J., Ivanova, S. M., & Tracey, K. J. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011714 · Cited by 529
Self-citationPathogenesis of septic shock in Pseudomonas aeruginosa pneumonia
Kurahashi, K., Kajikawa, O., Sawa, T., Ohara, M., Gropper, M. A., Frank, D. W., Martin, T. R., & Wiener-Kronish, J. P. (1999) · Journal of Clinical Investigation · doi:10.1172/jci7124 · Cited by 316
Cited by
The acute respiratory distress syndrome
Matthay, M. A., Ware, L. B., & Zimmerman, G. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60331 · Cited by 1,706
Self-citationReutershan, J., Basit, A., Galkina, E. V., & Ley, K. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00477.2004 · Cited by 309
Birukova, A. A., Zagranichnaya, T., Fu, P., Alekseeva, E., Chen, W., Jacobson, J. R., & Birukov, K. G. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.03.036 · Cited by 285
Clinical characteristics and outcomes of sepsis-related vs non-sepsis-related ARDS.
Sheu, C.-C., Gong, M. N., Zhai, R., Chen, F., Bajwa, E. K., Clardy, P. F., Gallagher, D. C., Thompson, B. T., & Christiani, D. C. (2010) · Chest · doi:10.1378/chest.09-2933 · Cited by 260
Ascorbic acid attenuates lipopolysaccharide-induced acute lung injury.
Fisher, B. J., Seropian, I. M., Kraskauskas, D., Thakkar, J. N., Voelkel, N. F., Fowler, A. A., & Natarajan, R. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182120cb8 · Cited by 178
Metadata
- Authors
- Matthay, M. A., Zimmerman, G. A., Esmon, C., Bhattacharya, J., Coller, B., Doerschuk, C. M., Floros, J., Gimbrone, M. A., Hoffman, E., Hubmayr, R. D., Leppert, M., Matalon, S., Munford, R., Parsons, P., Slutsky, A. S., Tracey, K. J., Ward, P., Gail, D. B., & Harabin, A. L.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-04-01
- Volume
- 167
- Issue
- 7
- Pages
- 1027-1035
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W1892829132
- Cited by
- 496
- References
- 6
- FWCI
- 22.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Matthay, M. A., Zimmerman, G. A., Esmon, C., Bhattacharya, J., Coller, B., Doerschuk, C. M., Floros, J., Gimbrone, M. A., Hoffman, E., Hubmayr, R. D., Leppert, M., Matalon, S., Munford, R., Parsons, P., Slutsky, A. S., Tracey, K. J., Ward, P., Gail, D. B., & Harabin, A. L. (2003). Future Research Directions in Acute Lung Injury: Summary of a National Heart, Lung, and Blood Institute Working Group. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200208-966ws
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.