The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Ventilatory Control and Airway Anatomy in Obstructive Sleep Apnea
Open accessAbstract
Ventilatory instability may play an important role in the pathogenesis of obstructive sleep apnea. We hypothesized that the influence of ventilatory instability in this disorder would vary depending on the underlying collapsibility of the upper airway. To test this hypothesis, we correlated loop gain with apnea-hypopnea index during supine, nonrapid eye movement sleep in three groups of patients with obstructive sleep apnea based on pharyngeal closing pressure: negative pressure group (pharyngeal closing pressure less than -1 cm H(2)O), atmospheric pressure group (between -1 and +1 cm H(2)O), and positive pressure group (greater than +1 cm H(2)O). Loop gain was measured by sequentially increasing proportional assist ventilation until periodic breathing developed, which occurred in 24 of 25 subjects. Mean loop gain for all three groups was 0.37 +/- 0.11. A significant correlation was found between loop gain and apnea-hypopnea index in the atmospheric group only (r = 0.88, p = 0.0016). We conclude that loop gain has a substantial impact on apnea severity in certain patients with sleep apnea, particularly those with a pharyngeal closing pressure near atmospheric.
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Cites
McNicholas, W. T., Strohl, K. P., White, D. P., Levy, P. A., Schmidt, W., Wheatley, J. R., Redline, S. S., Carley, D. W., Buysse, D. J., Young, T. B., et al. (1999) · PubMed · Cited by 3,665
Self-citationAnatomy of pharynx in patients with obstructive sleep apnea and in normal subjects
Isono, S., Remmers, J. E., Tanaka, A., Sho, Y., Sato, J., & Nishino, T. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.4.1319 · Cited by 534
Proportional Assist Ventilation, a New Approach to Ventilatory Support: Theory
Younes, M. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/145.1.114 · Cited by 491
Update in Intensive Care and Emergency Medicine
Vincent, J. L., Haspel, K. L., & Chernow, B. (1989) · Critical Care Medicine · doi:10.1097/00003246-198906000-00035 · Cited by 483
Upper Airway Collapsibility in Snorers and in Patients with Obstructive Hypopnea and Apnea
Gleadhill, I. C., Schwartz, A. R., Schubert, N., Wise, R. A., Permutt, S., & Smith, P. L. (1991) · American Review of Respiratory Disease · doi:10.1164/ajrccm/143.6.1300 · Cited by 453
Chemical Control Stability in Patients with Obstructive Sleep Apnea
YOUNES, M., OSTROWSKI, M., THOMPSON, W., LESLIE, C., & SHEWCHUK, W. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.5.2007013 · Cited by 439
Pharyngeal narrowing/occlusion during central sleep apnea
Badr, M. S., Toiber, F., Skatrud, J. B., & Dempsey, J. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.5.1806 · Cited by 360
Upper Airway Morphology in Patients with Idiopathic Obstructive Sleep Apnea
RIVLIN, J., HOFFSTEIN, V., KALBFLEISCH, J., McNICHOLS, W., ZAMEL, N., & BRYAN, A. C. (1985) · Survey of Anesthesiology · doi:10.1097/00132586-198502000-00041 · Cited by 256
Control of genioglossus muscle inspiratory activity
Brouillette, R. T., & Thach, B. T. (1980) · Journal of Applied Physiology · doi:10.1152/jappl.1980.49.5.801 · Cited by 228
Cited by
Pathophysiology of Sleep Apnea
Dempsey, J. A., Veasey, S. C., Morgan, B. J., & O'Donnell, C. P. (2010) · Physiological Reviews · doi:10.1152/physrev.00043.2008 · Cited by 2,243
Adult obstructive sleep apnoea
Jordan, A. S., McSharry, D. G., & Malhotra, A. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60734-5 · Cited by 1,735
Self-citationGoldberger, J. J., Cain, M. E., Hohnloser, S. H., Kadish, A. H., Knight, B. P., Lauer, M. S., Maron, B. J., Page, R. L., Passman, R. S., Siscovick, D., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.189375 · Cited by 1,450
Somers, V. K., White, D. P., Amin, R., Abraham, W. T., Costa, F., Culebras, A., Daniels, S., Floras, J. S., Hunt, C. E., Olson, L. J., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.189420 · Cited by 1,297
Self-citationDefining Phenotypic Causes of Obstructive Sleep Apnea. Identification of Novel Therapeutic Targets
Eckert, D. J., White, D. P., Jordan, A. S., Malhotra, A., & Wellman, A. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201303-0448oc · Cited by 1,173
Self-citation
Metadata
- Authors
- Wellman, A., Jordan, A. S., Malhotra, A., Fogel, R. B., Katz, E. S., Schory, K., Edwards, J. K., & White, D. P.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-12-01
- Volume
- 170
- Issue
- 11
- Pages
- 1225-1232
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2132327194
- Cited by
- 317
- References
- 47
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Wellman, A., Jordan, A. S., Malhotra, A., Fogel, R. B., Katz, E. S., Schory, K., Edwards, J. K., & White, D. P. (2004). Ventilatory Control and Airway Anatomy in Obstructive Sleep Apnea. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200404-510oc
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