The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Procalcitonin Kinetics as a Prognostic Marker of Ventilator-associated Pneumonia
Abstract
We investigated the value of procalcitonin kinetics as a prognostic marker during ventilator-associated pneumonia (VAP). This prospective, observational study was conducted in a medical intensive care unit in a university hospital. All consecutive patients with microbiologically proven VAP who survived 3 days after its diagnosis were included and grouped according to clinical outcome: favorable or unfavorable, defined as death, VAP recurrence, or extrapulmonary infection requiring antibiotics before Day 28. Serum procalcitonin levels were measured on Days 1, 3, and 7 for all patients. Among the 63 patients included, 38 had unfavorable outcomes. On Day 1, they were more critically ill than patients with a favorable outcome. Serum procalcitonin levels decreased during the clinical course of VAP but were significantly higher from Day 1 to Day 7 in patients with unfavorable outcomes. Multivariate analyses retained serum procalcitonin levels on Days 1, 3, and 7 as strong predictors of unfavorable outcome. Based on these data, procalcitonin could be a prognostic marker of outcome during VAP.
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Ventilator-associated Pneumonia
Chastre, J., & Fagon, J.-Y. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.7.2105078 · Cited by 2,812
Self-citationPetry, F. E. (1997) · Kluwer Academic Publishers eBooks · Cited by 2,303
High serum procalcitonin concentrations in patients with sepsis and infection
Assicot, M., Bohuon, C., Gendrel, D., Raymond, J., Carsin, H., & Guilbaud, J. (1993) · The Lancet · doi:10.1016/0140-6736(93)90277-n · Cited by 2,197
Chastre, J., Wolff, M., Fagon, J.-Y., Chevret, S., Thomas, F., Wermert, D., Clementi, E., Gonzalez, J., Jusserand, D., Asfar, P., et al. (2003) · JAMA · doi:10.1001/jama.290.19.2588 · Cited by 1,376
Self-citationKreger, B. E., Craven, D. E., & McCabe, W. R. (1980) · The American Journal of Medicine · doi:10.1016/0002-9343(80)90102-3 · Cited by 1,314
Fagon, J.-Y., Chastre, J., Hance, A. J., Montravers, P., Novara, A., & Gibert, C. (1993) · The American Journal of Medicine · doi:10.1016/0002-9343(93)90060-3 · Cited by 1,180
Self-citationChrist-Crain, M., Jaccard-Stolz, D., Bingisser, R., Gencay, M. M., Huber, P. R., Tamm, M., & Müller, B. (2004) · The Lancet · doi:10.1016/s0140-6736(04)15591-8 · Cited by 1,096
Incidence, Risk, and Prognosis Factors of Nosocomial Pneumonia in Mechanically Ventilated Patients
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Cited by
Torres, A., Niederman, M. S., Chastre, J., Ewig, S., Fernandez-Vandellos, P., Hanberger, H., Kollef, M., Li Bassi, G., Luna, C. M., Martin-Loeches, I., et al. (2017) · European Respiratory Journal · doi:10.1183/13993003.00582-2017 · Cited by 1,387
Self-citationBouadma, L., Luyt, C.-E., Tubach, F., Cracco, C., Alvarez, A., Schwebel, C., Schortgen, F., Lasocki, S., Veber, B., Dehoux, M., et al. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61879-1 · Cited by 1,183
Self-citationProcalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection
Huang, D. T., Yealy, D. M., Filbin, M. R., Brown, A. M., Chang, C.-C. H., Doi, Y., Donnino, M. W., Fine, J., Fine, M. J., Fischer, M. A., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1802670 · Cited by 434
Jensen, J. U., Hein, L., Lundgren, B., Bestle, M. H., Mohr, T. T., Andersen, M. H., Thornberg, K. J., Løken, J., Steensen, M., Fox, Z., et al. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e31821e8791 · Cited by 356
Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study
Stolz, D., Smyrnios, N., Eggimann, P., Pargger, H., Thakkar, N., Siegemund, M., Marsch, S., Azzola, A., Rakic, J., Mueller, B., et al. (2009) · European Respiratory Journal · doi:10.1183/09031936.00053209 · Cited by 327
Metadata
- Authors
- Luyt, C.-E., Guérin, V., Combes, A., Trouillet, J.-L., Ayed, S. B., Bernard, M., Gibert, C., & Chastre, J.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-01-01
- Volume
- 171
- Issue
- 1
- Pages
- 48-53
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2101854308
- Cited by
- 288
- References
- 30
- FWCI
- 14.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Luyt, C.-E., Guérin, V., Combes, A., Trouillet, J.-L., Ayed, S. B., Bernard, M., Gibert, C., & Chastre, J. (2005). Procalcitonin Kinetics as a Prognostic Marker of Ventilator-associated Pneumonia. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200406-746oc
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