The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Reversibility of Lung Collapse and Hypoxemia in Early Acute Respiratory Distress Syndrome
Abstract
RATIONALE: The hypothesis that lung collapse is detrimental during the acute respiratory distress syndrome is still debatable. One of the difficulties is the lack of an efficient maneuver to minimize it. OBJECTIVES: To test if a bedside recruitment strategy, capable of reversing hypoxemia and collapse in > 95% of lung units, is clinically applicable in early acute respiratory distress syndrome. METHODS: Prospective assessment of a stepwise maximum-recruitment strategy using multislice computed tomography and continuous blood-gas hemodynamic monitoring. MEASUREMENTS AND MAIN RESULTS: Twenty-six patients received sequential increments in inspiratory airway pressures, in 5 cm H(2)O steps, until the detection of Pa(O(2)) + Pa(CO(2)) >or= 400 mm Hg. Whenever this primary target was not met, despite inspiratory pressures reaching 60 cm H(2)O, the maneuver was considered incomplete. If there was hemodynamic deterioration or barotrauma, the maneuver was to be interrupted. Late assessment of recruitment efficacy was performed by computed tomography (9 patients) or by online continuous monitoring in the intensive care unit (15 patients) up to 6 h. It was possible to open the lung and to keep the lung open in the majority (24/26) of patients, at the expense of transient hemodynamic effects and hypercapnia but without major clinical consequences. No barotrauma directly associated with the maneuver was detected. There was a strong and inverse relationship between arterial oxygenation and percentage of collapsed lung mass (R = - 0.91; p < 0.0001). CONCLUSIONS: It is often possible to reverse hypoxemia and fully recruit the lung in early acute respiratory distress syndrome. Due to transient side effects, the required maneuver still awaits further evaluation before routine clinical application.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941
Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome.
Amato, M. B. P., Barbas, C. S. V., Medeiros, D. M., Magaldi, R. B., Schettino, G. P., Lorenzi-Filho, G., Kairalla, R. A., Deheinzelin, D., Munoz, C., Oliveira, R., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199802053380602 · Cited by 3,654
Self-citationAmato, M. B., Barbas, C. S., Medeiros, D. M., Schettino, G. D. P., Lorenzi Filho, G., Kairalla, R. A., Deheinzelin, D., Morais, C., Fernandes, E. D. O., & Takagaki, T. Y. (1995) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.152.6.8520744 · Cited by 625
Self-citationVentilatory management of acute respiratory distress syndrome: A consensus of two.
Marini, J. J., & Gattinoni, L. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000104946.66723.a8 · Cited by 168
Cited by
Writing Group for the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) Investigators, Cavalcanti, A. B., Suzumura, É. A., Laranjeira, L. N., Paisani, D. D. M., Damiani, L. P., Guimarães, H. P., Romano, E. R., Regenga, M. D. M., Taniguchi, L. N. T., et al. (2017) · JAMA · doi:10.1001/jama.2017.14171 · Cited by 1,018
Self-citationFormal guidelines: Management of acute respiratory distress syndrome.
Papazian, L., Aubron, C., Brochard, L., Chiche, J.-D., Combes, A., Dreyfuss, D., Forel, J.-M., Guérin, C., Jaber, S., Mekontso-Dessap, A., et al. (2019) · Annals of Intensive Care · doi:10.1186/s13613-019-0540-9 · Cited by 761
Wearable and flexible sensors for user-interactive health-monitoring devices
Ha, M., Lim, S., & Ko, H. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb01063c · Cited by 352
Recruitment Maneuvers for Acute Lung Injury
Fan, E., Wilcox, M. E., Brower, R. G., Stewart, T. E., Mehta, S., Lapinsky, S. E., Meade, M. O., & Ferguson, N. D. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200802-335oc · Cited by 328
Kacmarek, R. M., Villar, J., Sulemanji, D., Montiel, R., Ferrando, C., Blanco, J., Koh, Y., Soler, J. A., Martínez, D., Hernández, M., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001383 · Cited by 288
Self-citationGoligher, E. C., Kavanagh, B. P., Rubenfeld, G. D., Adhikari, N. K. J., Pinto, R., Fan, E., Brochard, L. J., Granton, J. T., Mercat, A., Marie Richard, J.-C., et al. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201404-0688oc · Cited by 194
Hodgson, C. L., Cooper, D. J., Arabi, Y., King, V., Bersten, A., Bihari, S., Brickell, K., Davies, A., Fahey, C., Fraser, J., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201901-0109oc · Cited by 159
Nieman, G. F., Satalin, J., Andrews, P., Aiash, H., Habashi, N. M., & Gatto, L. A. (2017) · Intensive Care Medicine Experimental · doi:10.1186/s40635-017-0121-x · Cited by 143
Metadata
- Authors
- Borges, J. B., Okamoto, V. N., Matos, G. F. J., Caramez, M. P. R., Arantes, P. R., Barros, F., Souza, C. E., Victorino, J. A., Kacmarek, R. M., Barbas, C. S. V., Carvalho, C. R. R., & Amato, M. B. P.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-08-01
- Volume
- 174
- Issue
- 3
- Pages
- 268-278
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2120034179
- Cited by
- 516
- References
- 4
- FWCI
- 31.66
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
