Mechanisms of Dyspnea during Cycle Exercise in Symptomatic Patients with GOLD Stage I Chronic Obstructive Pulmonary Disease

Ofir, Dror; Laveneziana, Pierantonio; Webb, Katherine A.; Lam, Yuk-Miu; O'Donnell, Denis E.

doi:10.1164/rccm.200707-1064oc

Mechanisms of Dyspnea during Cycle Exercise in Symptomatic Patients with GOLD Stage I Chronic Obstructive Pulmonary Disease

Rationale Smokers with a relatively preserved FEV(1) may experience dyspnea and activity limitation but little is known about underlying mechanisms. Objectives To examine ventilatory constraints during exercise in symptomatic smokers with GOLD (Global Initiative for Chronic Obstructive Lung Disea…