Cited by 349Air Quality and Health ImpactsAsthma and respiratory diseasesIndoor Air Quality and Microbial Exposure

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Short-term Associations between Ambient Air Pollutants and Pediatric Asthma Emergency Department Visits

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Strickland, Matthew J., Darrow, Lyndsey A., Klein, Mitchel, Flanders, W. Dana, Sarnat, Jeremy A., Waller, Lance A., Sarnat, Stefanie E., Mulholland, James A., Tolbert, Paige E.·2010·American Journal of Respiratory and Critical Care Medicine

DOI 10.1164/rccm.200908-1201ocPMC PMC2921597

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Abstract

RATIONALE: Certain outdoor air pollutants cause asthma exacerbations in children. To advance understanding of these relationships, further characterization of the dose-response and pollutant lag effects are needed, as are investigations of pollutant species beyond the commonly measured criteria pollutants. OBJECTIVES: Investigate short-term associations between ambient air pollutant concentrations and emergency department visits for pediatric asthma. METHODS: Daily counts of emergency department visits for asthma or wheeze among children aged 5 to 17 years were collected from 41 Metropolitan Atlanta hospitals during 1993-2004 (n = 91,386 visits). Ambient concentrations of gaseous pollutants and speciated particulate matter were available from stationary monitors during this time period. Rate ratios for the warm season (May to October) and cold season (November to April) were estimated using Poisson generalized linear models in the framework of a case-crossover analysis. MEASUREMENTS AND MAIN RESULTS: Both ozone and primary pollutants from traffic sources were associated with emergency department visits for asthma or wheeze; evidence for independent effects of ozone and primary pollutants from traffic sources were observed in multipollutant models. These associations tended to be of the highest magnitude for concentrations on the day of the emergency department visit and were present at relatively low ambient concentrations. CONCLUSIONS: Even at relatively low ambient concentrations, ozone and primary pollutants from traffic sources independently contributed to the burden of emergency department visits for pediatric asthma.

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Authors: Strickland, M. J., Darrow, L. A., Klein, M., Flanders, W. D., Sarnat, J. A., Waller, L. A., Sarnat, S. E., Mulholland, J. A., & Tolbert, P. E.
Affiliations: Department of Environmental Health
Department of Epidemiology, and
Emory University (US)
Georgia Institute of Technology (US)
ORCID: Strickland, Matthew J.
Darrow, Lyndsey A.
Flanders, W. Dana
Sarnat, Jeremy A.
Waller, Lance A.
Mulholland, James A.
Venue: American Journal of Respiratory and Critical Care Medicine
Publisher: Oxford University Press (OUP)
Published: 2010-08-01
Volume: 182
Issue: 3
Pages: 307-316
ISSN: 1073-449X (ISSN-L)
1535-4970
DOI: 10.1164/rccm.200908-1201oc
PMC: PMC2921597
OpenAlex: W2166246487
Cited by: 349
References: 52
Citations by year: 2026: 9 · 2025: 14 · 2024: 15 · 2023: 10 · 2022: 16 · 2021: 19 · 2020: 35 · 2019: 35 · 2018: 29 · 2017: 20 · 2016: 28 · 2015: 24 · 2014: 28 · 2013: 21 · 2012: 20
FWCI: 16.37
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: American Journal of Respiratory and Critical Care Medicine (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Electric Power Research Institute (EP-P27723/C13172)
Topics: Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
Keywords: childhood asthma, emergency department visits, ambient air pollution, ozone, traffic-related pollutants, particulate matter, wheezing, short-term exposure, dose-response relationship, lagged effects, seasonal variation, Atlanta
MeSH terms: Adolescent, Air Pollutants, Asthma, Vehicle Emissions, Child, Child, Preschool, Emergency Service, Hospital, Environmental Monitoring, Georgia, Humans, Ozone, Respiratory Sounds, Seasons, Linear Models, Particulate Matter, Epidemiological Monitoring

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Short-term Associations between Ambient Air Pollutants and Pediatric Asthma Emergency Department Visits

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