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Practice Recommendations in the Diagnosis, Management, and Prevention of Carbon Monoxide Poisoning

Hampson, Neil B., Piantadosi, Claude A., Thom, Stephen R., Weaver, Lindell K.·2012·American Journal of Respiratory and Critical Care Medicine

Abstract

Carbon monoxide (CO) poisoning is common in modern society, resulting in significant morbidity and mortality in the United States annually. Over the past two decades, sufficient information has been published about carbon monoxide poisoning in the medical literature to draw firm conclusions about many aspects of the pathophysiology, diagnosis, and clinical management of the syndrome, along with evidence-based recommendations for optimal clinical practice. This article provides clinical practice guidance to the pulmonary and critical care community regarding the diagnosis, management, and prevention of acute CO poisoning. The article represents the consensus opinion of four recognized content experts in the field. Supporting data were drawn from the published, peer-reviewed literature on CO poisoning, placing emphasis on selecting studies that most closely mirror clinical practice.

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Research works printed but not linked: 87

  1. Hampson, 2007, Carbon monoxide poisoning: a new incidence for an old disease, Undersea Hyperb Med, 34, 163
  2. Weaver, 2007, Carbon monoxide poisoning: risk factors for cognitive sequelae and the role of hyperbaric oxygen, Am J Respir Crit Care Med, 176, 491, 10.1164/rccm.200701-026OC · DOI
  3. Hampson, 2008, Carboxyhemoglobin levels in carbon monoxide poisoning: do they correlate with the clinical picture?, Am J Emerg Med, 26, 665, 10.1016/j.ajem.2007.10.005 · DOI
  4. Goldbaum, 1976, Mechanism of the toxic action of carbon monoxide, Ann Clin Lab Sci, 6, 372
  5. Brown, 1989, Reversal of carbon monoxide–cytochrome c oxidase binding by hyperbaric oxygen in vivo, Adv Exp Med Biol, 248, 747, 10.1007/978-1-4684-5643-1_84 · DOI
  6. Brown, 1990, In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain, J Appl Physiol, 68, 604, 10.1152/jappl.1990.68.2.604 · DOI
  7. Brown, 1992, Recovery of energy metabolism in rat brain after carbon monoxide hypoxia, J Clin Invest, 89, 666, 10.1172/JCI115633 · DOI
  8. Piantadosi, 1997, Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat, Exp Neurol, 147, 103, 10.1006/exnr.1997.6584 · DOI
  9. Thom, 1990, Antagonism of carbon monoxide–mediated brain lipid peroxidation by hyperbaric oxygen, Toxicol Appl Pharmacol, 105, 340, 10.1016/0041-008X(90)90195-Z · DOI
  10. Thom, 2004, Delayed neuropathology after carbon monoxide poisoning is immune-mediated, Proc Natl Acad Sci USA, 101, 13660, 10.1073/pnas.0405642101 · DOI
  11. Thom, 2006, Hyperbaric oxygen reduces delayed immune-mediated neuropathology in experimental carbon monoxide toxicity, Toxicol Appl Pharmacol, 213, 152, 10.1016/j.taap.2005.10.006 · DOI
  12. Thom, 2006, Intravascular neutrophil activation due to carbon monoxide poisoning, Am J Respir Crit Care Med, 74, 1239, 10.1164/rccm.200604-557OC · DOI
  13. Thom, 2010, Plasma biomarkers in carbon monoxide poisoning, Clin Toxicol (Phila), 48, 47, 10.3109/15563650903468209 · DOI
  14. Weaver, 2009, Clinical practice: carbon monoxide poisoning, N Engl J Med, 369, 1217, 10.1056/NEJMcp0808891 · DOI · Paper page
  15. Coburn, 1973, Endogenous carbon monoxide metabolism, Annu Rev Med, 24, 241, 10.1146/annurev.me.24.020173.001325 · DOI
  16. Motterlini, 2010, The therapeutic potential of carbon monoxide, Nat Rev Drug Discov, 9, 728, 10.1038/nrd3228 · DOI
  17. Hampson, 2012, Symptoms of acute carbon monoxide poisoning do not correlate with the initial carboxyhemoglobin level, Undersea Hyperb Med, 39, 657
  18. Hampson, 2002, Characteristics of the headache associated with acute carbon monoxide poisoning, Headache, 42, 220, 10.1046/j.1526-4610.2002.02055.x · DOI
  19. Simini, 1988, Cherry-red discolouration in carbon monoxide poisoning, Lancet, 352, 1154, 10.1016/S0140-6736(05)79807-X · DOI
  20. Gorman, 1992, A longitudinal study of 100 consecutive admissions for carbon monoxide poisoning to the Royal Adelaide Hospital, Anaesth Intensive Care, 20, 311, 10.1177/0310057X9202000306 · DOI
  21. Hoppe, 1857, Uber die Einwirkung des Kohlenoxydgases auf das Hämatoglobulin, Virchows Arch Pathol Anat Physiol Klin Med, 11, 288, 10.1007/BF01995373 · DOI
  22. Findlay, 1988, Carbon monoxide poisoning: optics and histology of skin and blood, Br J Dermatol, 119, 45, 10.1111/j.1365-2133.1988.tb07099.x · DOI
  23. Istvan, 1992, Smoking rate, carboxyhemoglobin, and body mass in the Second National Health and Nutrition Examination Survey (NHANES II), J Behav Med, 15, 559, 10.1007/BF00844856 · DOI
  24. Aker, 1987, Carboxyhemoglobin levels in banked blood: a comparison of cigarette smokers and nonsmokers, AANA J, 55, 421
  25. Sen, 2010, Recurrent carbon monoxide poisoning from cigarette smoking, Am J Med Sci, 340, 427, 10.1097/MAJ.0b013e3181ef712d · DOI
  26. Hampson, 2008, Stability of carboxyhemoglobin in stored and mailed blood samples, Am J Emerg Med, 26, 191, 10.1016/j.ajem.2007.04.028 · DOI
  27. Lopez, 2000, Relationship between arterial, mixed venous, and internal jugular carboxyhemoglobin concentrations at low, medium, and high concentrations in a piglet model of carbon monoxide toxicity, Crit Care Med, 28, 1998, 10.1097/00003246-200006000-00053 · DOI
  28. Touger, 1995, Relationship between venous and arterial carboxyhemoglobin levels in patients with suspected carbon monoxide poisoning, Ann Emerg Med, 25, 481, 10.1016/S0196-0644(95)70262-8 · DOI
  29. Hampson, 1998, Pulse oximetry in severe carbon monoxide poisoning, Chest, 114, 1036, 10.1378/chest.114.4.1036 · DOI
  30. Barker, 2006, Measurement of carboxyhemoglobin and methemoglobin by pulse oximetry: a human volunteer study, Anesthesiology, 105, 892, 10.1097/00000542-200611000-00008 · DOI
  31. Hampson, 2006, Noninvasive CO measurement by first responders: a suggested management algorithm, J Emerg Med Serv JEMS, 24, 10
  32. Touger, 2010, Performance of the RAD-57 pulse CO-oximeter compared with standard laboratory carboxyhemoglobin measurement, Ann Emerg Med, 56, 382, 10.1016/j.annemergmed.2010.03.041 · DOI
  33. Weaver, False positive rate of carbon monoxide saturation by pulse oximetry of emergency department patients, Respir Care
  34. Piatkowski, 2009, A new tool for the early diagnosis of carbon monoxide intoxication, Inhal Toxicol, 21, 1144, 10.3109/08958370902839754 · DOI
  35. Roth, 2011, Accuracy of noninvasive multiwave pulse oximetry compared with carboxyhemoglobin from blood gas analysis in unselected emergency department patients, Ann Emerg Med, 58, 74, 10.1016/j.annemergmed.2010.12.024 · DOI
  36. Henderson, 1920, The elimination of carbon monoxide from the blood after a dangerous degree of asphyxiation, and a therapy for accelerating the elimination, J Pharmacol Exp Ther, 16, 11, 10.1016/S0022-3565(25)09271-7 · DOI
  37. Donald, 1955, Gases administered in artificial respiration; with particular reference to the use of carbon dioxide, BMJ, 1, 313, 10.1136/bmj.1.4909.313 · DOI
  38. Fisher, 2011, Rapid elimination of CO through the lungs: coming full circle 100 years on, Exp Physiol, 96, 1262, 10.1113/expphysiol.2011.059428 · DOI
  39. Weaver, 2000, Carboxyhemoglobin half-life in carbon monoxide poisoned patients treated with 100% oxygen at atmospheric pressure, Chest, 117, 801, 10.1378/chest.117.3.801 · DOI · Paper page
  40. Peterson, 1970, Absorption and elimination of carbon monoxide by inactive young men, Arch Environ Health, 21, 165, 10.1080/00039896.1970.10667215 · DOI
  41. Raphael, 1989, Trial of normobaric and hyperbaric oxygen for acute carbon monoxide intoxication, Lancet, 2, 414, 10.1016/S0140-6736(89)90592-8 · DOI
  42. Ducasse, 1995, Non-comatose patients with acute carbon monoxide poisoning: hyperbaric or normobaric oxygenation?, Undersea Hyperb Med, 22, 9
  43. Thom, 1995, Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention with hyperbaric oxygen, Ann Emerg Med, 25, 474, 10.1016/S0196-0644(95)70261-X · DOI
  44. Mathieu, 1996, Randomized prospective study comparing the effect of HBO2 versus 12 hours of NBO in non comatose CO poisoned patients: results of the interim analysis [abstract], Undersea Hyperb Med, 23, 7
  45. Scheinkestel, 1999, Trial of normobaric and hyperbaric oxygen for acute carbon monoxide poisoning: a randomized controlled clinical trial, Med J Aust, 170, 203, 10.5694/j.1326-5377.1999.tb140318.x · DOI
  46. Weaver, 2002, Hyperbaric oxygen for acute carbon monoxide poisoning, N Engl J Med, 347, 1057, 10.1056/NEJMoa013121 · DOI
  47. Annane, 2011, Hyperbaric oxygen for acute domestic carbon monoxide poisoning: two randomized controlled trials, Intensive Care Med, 37, 486, 10.1007/s00134-010-2093-0 · DOI
  48. Hampson, 2001, Carbon monoxide poisoning: Interpretation of randomized clinical trials and unresolved treatment issues, Undersea Hyperb Med, 28, 157
  49. Hampson, 2004, Acute carbon monoxide poisoning and the role of hyperbaric oxygen, Emerg Med Australas, 16, 481
  50. Wolf, 2008, Clinical policy: critical issues in the management of adult patients presenting to the emergency department with acute carbon monoxide poisoning, Ann Emerg Med, 51, 138, 10.1016/j.annemergmed.2007.10.012 · DOI
  51. Hsaio, 2004, Delayed encephalopathy after carbon monoxide intoxication—long-term prognosis and correlation of clinical manifestations and neuroimages, Acta Neurol Taiwan, 13, 64
  52. Weaver, 2004, LDS Hospital, Utah in response to Scheinkestel et al. and Emerson: the role of hyperbaric oxygen in carbon monoxide poisoning, Emerg Med Australas, 16, 394
  53. Raub, 2002, Carbon monoxide and the nervous system, Neurosci Biobehav Rev, 26, 925, 10.1016/S0149-7634(03)00002-2 · DOI
  54. Chambers, 2008, Cognitive and affective outcomes of more severe compared to less severe carbon monoxide poisoning, Brain Inj, 22, 387, 10.1080/02699050802008075 · DOI
  55. Piatt, 1990, Occult carbon monoxide poisoning in an infant, Pediatr Emerg Care, 6, 21, 10.1097/00006565-199003000-00007 · DOI
  56. Foster, 1999, Recurrent acute life-threatening events and lactic acidosis caused by chronic carbon monoxide poisoning in an infant, Pediatrics, 104, e34, 10.1542/peds.104.3.e34 · DOI
  57. Klasner, 1998, Carbon monoxide mass exposure in a pediatric population, Acad Emerg Med, 5, 992, 10.1111/j.1553-2712.1998.tb02778.x · DOI
  58. Hampson, 1992, Carbon monoxide poisoning in children riding in the back of pickup trucks, JAMA, 267, 538, 10.1001/jama.1992.03480040086036 · DOI
  59. Tsugang, 1996, Impact of a sample selection on APOE ε4 allele frequency: a comparison of two Alzheimer’s disease samples, J Am Geriatr Soc, 44, 704, 10.1111/j.1532-5415.1996.tb01836.x · DOI · Paper page
  60. Ignatius, 1986, Expression of apolipoprotein E during nerve degeneration and regeneration, Proc Natl Acad Sci USA, 83, 1125, 10.1073/pnas.83.4.1125 · DOI
  61. Aamar, 1992, Lesion-induced changes in the production of newly synthesized and secreted apo-E and other molecules are independent of the concomitant recruitment of blood-borne macrophages into injury peripheral nerves, J Neurochem, 59, 1287, 10.1111/j.1471-4159.1992.tb08439.x · DOI
  62. Friedman, 1999, Apolipoprotein E-ε4 genotype predicts a poor outcome in survivors of traumatic brain injury, Neurology, 52, 244, 10.1212/WNL.52.2.244 · DOI
  63. McCarron, 2003, Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage, Acta Neurol Scand, 107, 106, 10.1034/j.1600-0404.2003.01365.x · DOI
  64. Grocett, 2001, Apolipoprotein E genotype differentially influences the proinflammatory and anti-inflammatory response to cardiopulmonary bypass, J Thorac Cardiovasc Surg, 122, 622, 10.1067/mtc.2001.115152 · DOI
  65. Hopkins, 2007, Apolipoprotein E genotype and response of carbon monoxide poisoning to hyperbaric oxygen treatment, Am J Respir Crit Care Med, 176, 1001, 10.1164/rccm.200702-290OC · DOI
  66. Hampson, 2001, Outcome of patients experiencing cardiac arrest with carbon monoxide poisoning and treated with hyperbaric oxygen, Ann Emerg Med, 38, 36, 10.1067/mem.2001.115532 · DOI
  67. Hampson, 2008, Risk factors for short-term mortality from carbon monoxide poisoning treated with hyperbaric oxygen, Crit Care Med, 36, 2523, 10.1097/CCM.0b013e31818419d8 · DOI
  68. Hampson, 2012, The UHMS/CDC carbon monoxide poisoning surveillance program: three-year data, Undersea Hyperb Med, 39, 667
  69. Hampson, 2005, Hyperbaric treatment of patients with carbon monoxide poisoning in the United States, Undersea Hyperb Med, 32, 21
  70. Hampson, Frequency of toxic co-ingestions in intentional carbon monoxide poisoning, J Emerg Med
  71. Baud, 2007, Cyanide: critical issues in diagnosis and treatment, Hum Exp Toxicol, 26, 191, 10.1177/0960327107070566 · DOI
  72. Lawson-Smith, 2011, Cyanide intoxication as part of smoke inhalation: a review on diagnosis and treatment from the emergency perspective, Scand J Traum Resusc Emerg Med, 19, 14, 10.1186/1757-7241-19-14 · DOI
  73. Chou, 2000, Characteristics and outcome of children with carbon monoxide poisoning with and without smoke exposure referred for hyperbaric oxygen therapy, Pediatr Emerg Care, 16, 151, 10.1097/00006565-200006000-00002 · DOI
  74. Toon, 2010, Management of acute smoke inhalation injury, Crit Care Resusc, 12, 53
  75. Smith, 1973, Morbidity from carbon monoxide poisoning at three-year follow-up, BMJ, 1, 318, 10.1136/bmj.1.5849.318 · DOI
  76. Mimura, 1999, Long-term follow-up study on sequelae of carbon monoxide poisoning; serial investigation 33 years after poisoning, Seishin Shinkeigaku Zasshi, 101, 592
  77. Hopkins, 2008, Cognitive outcomes 6 years after acute carbon monoxide poisoning [abstract], Undersea Hyperb Med, 35, 258
  78. Weaver, 2008, Neurological outcomes 6 years after acute carbon monoxide poisoning [abstract], Undersea Hyperb Med, 35, 258
  79. Hampson, 2009, Increased long-term mortality among survivors of acute carbon monoxide poisoning, Crit Care Med, 37, 1941, 10.1097/CCM.0b013e3181a0064f · DOI
  80. Hampson, 1994, Accidental carbon monoxide poisoning resulting from indoor burning of charcoal briquets, JAMA, 271, 52, 10.1001/jama.1994.03510250068037 · DOI
  81. Clower, 2012, Recipients of hyperbaric oxygen therapy for carbon monoxide poisoning and exposure circumstances, Am J Emerg Med, 30, 846, 10.1016/j.ajem.2011.05.028 · DOI
  82. Hampson, 2012, Partnering with a medical society to perform online disease surveillance, Undersea Hyperb Med, 39, 647
  83. Hampson, 2006, Storm-related carbon monoxide poisoning: lessons learned from recent epidemics, Undersea Hyperb Med, 33, 257
  84. Weaver, 2007, Carbon monoxide poisoning at hotels, motels, and resorts, Am J Prev Med, 33, 23, 10.1016/j.amepre.2007.02.038 · DOI
  85. Hampson, 2011, Residential carbon monoxide alarm use: opportunities for poisoning prevention, J Environ Health, 73, 30
  86. Hampson, 2012, Should the placement of carbon monoxide (CO) detectors be influenced by CO’s weight relative to air?, J Emerg Med, 42, 478, 10.1016/j.jemermed.2011.03.015 · DOI
  87. Ryan, 2011, Residential carbon monoxide detector failure rate in the United States, Am J Public Health, 101, e15, 10.2105/AJPH.2011.300274 · DOI

Cited by

Metadata

Authors
Hampson, N. B., Piantadosi, C. A., Thom, S. R., & Weaver, L. K.
Affiliations
  • Virginia Mason Medical Center, Seattle, Washington
  • Duke University Medical Center, Durham, North Carolina
  • University of Pennsylvania Medical Center, Philadelphia, Pennsylvania; and
  • Intermountain Medical Center, Salt Lake City, Utah
Venue
American Journal of Respiratory and Critical Care Medicine
Published
2012-12-01
Volume
186
Issue
11
Pages
1095-1101
ISSN
  • 1073-449X
  • 1535-4970
Cited by
331
References
0
Language
en

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